Aline Segatto Pires Altmann1, Fabrício Mezzomo Collares2, Vicente Castelo Branco Leitune1, Rodrigo Alex Arthur3, Antonio Shigueaki Takimi4, Susana Maria Werner Samuel1. 1. Dental Materials Laboratory, School of Dentistry, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2492, Rio Branco, Porto Alegre, RS, 90035-003, Brazil. 2. Dental Materials Laboratory, School of Dentistry, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos, 2492, Rio Branco, Porto Alegre, RS, 90035-003, Brazil. fabricio.collares@ufrgs.br. 3. Department of Preventive and Community Dentistry, School of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil. 4. Laboratory of Ceramic Materials, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.
Abstract
OBJECTIVES: White spot lesions are still a concern for orthodontic patients. The objective of this study was to assess the remineralizing and antibacterial effect of a newly developed orthodontic adhesive. METHODS: The compounds 1,3,5-tryacryloylhexahydro-1,3,5-triazine (TAT) and phosphate invert glass containing 10 mol% of niobium pentoxide (PIG-Nb) were added at 20 and 5 wt%, respectively, to an experimental adhesive (75 wt% BisGMA, 25 wt% TEGDMA, 5 wt% fummed silica, and photo-initiator system), called TPN. A group without the addition of these compounds was used as Control and the orthodontic adhesive Transbond XT (TXT) was used for comparison. Antibacterial activity was evaluated through surface biofilm formation, mineral deposition, and degree of conversion (DC) through Raman microscopy, Knoop hardness after softening in solvent, and bracket dislodgement (BD). RESULTS: TPN group presented a reduction in bacterial growth when compared to Control and TXT. Mineral deposits were observed on the surface of TPN adhesive after 14 and 28 days of immersion in artificial saliva. There was an increase in DC after 28 days, whereas TPN group presented the highest DC. All groups underwent some degree of softening. No significant changes were observed in BD after 28 days of immersion in artificial saliva. CONCLUSION: The newly developed orthodontic adhesive, with addition of 20 wt% TAT and 5w% PIG-Nb, exhibited antibacterial activity and was capable to induce mineral deposition on its surface in vitro. CLINICAL SIGNIFICANCE: The orthodontic adhesive developed in this study with antibacterial activity and mineral deposition could be a reliable choice for brackets adhesion.
OBJECTIVES: White spot lesions are still a concern for orthodontic patients. The objective of this study was to assess the remineralizing and antibacterial effect of a newly developed orthodontic adhesive. METHODS: The compounds 1,3,5-tryacryloylhexahydro-1,3,5-triazine (TAT) and phosphate invert glass containing 10 mol% of niobium pentoxide (PIG-Nb) were added at 20 and 5 wt%, respectively, to an experimental adhesive (75 wt% BisGMA, 25 wt% TEGDMA, 5 wt% fummed silica, and photo-initiator system), called TPN. A group without the addition of these compounds was used as Control and the orthodontic adhesive Transbond XT (TXT) was used for comparison. Antibacterial activity was evaluated through surface biofilm formation, mineral deposition, and degree of conversion (DC) through Raman microscopy, Knoop hardness after softening in solvent, and bracket dislodgement (BD). RESULTS: TPN group presented a reduction in bacterial growth when compared to Control and TXT. Mineral deposits were observed on the surface of TPN adhesive after 14 and 28 days of immersion in artificial saliva. There was an increase in DC after 28 days, whereas TPN group presented the highest DC. All groups underwent some degree of softening. No significant changes were observed in BD after 28 days of immersion in artificial saliva. CONCLUSION: The newly developed orthodontic adhesive, with addition of 20 wt% TAT and 5w% PIG-Nb, exhibited antibacterial activity and was capable to induce mineral deposition on its surface in vitro. CLINICAL SIGNIFICANCE: The orthodontic adhesive developed in this study with antibacterial activity and mineral deposition could be a reliable choice for brackets adhesion.
Entities:
Keywords:
Adhesive; Antibacterial; Mineral deposition; Orthodontic; WSL
Authors: Vicente Castelo Branco Leitune; Fabrício Mezzomo Collares; Rafael Mello Trommer; Daniela Guerra Andrioli; Carlos Pérez Bergmann; Susana Maria Werner Samuel Journal: J Dent Date: 2013-01-09 Impact factor: 4.379
Authors: V C B Leitune; A Takimi; F M Collares; P D Santos; C Provenzi; C P Bergmann; S M W Samuel Journal: Int Endod J Date: 2012-08-11 Impact factor: 5.264