Literature DB >> 26891462

Neurite outgrowth enhancement by jiadifenolide: possible targets.

R A Shenvi1.   

Abstract

Covering: 1860-2016A mechanistic link may exist between convulsant plant substances typified by picrotoxinin, and 'neurotrophic' sesquiterpenes like jiadifenolide. Picrotoxinin elicits convulsion by anion blockade of the Cys-loop family of neurotransmitter-gated ion channels. These same receptors mediate neuronal development and neurite outgrowth prior to synapse formation. Due to its structural homology with picrotoxin and anisatin, it is possible that jiadifenolide enhances NGF-stimulated neurite outgrowth by modulation of the Cys-loop family of receptors.

Entities:  

Mesh：

Substances：

Year:  2016        PMID： 26891462     DOI： 10.1039/c5np00160a

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  8 in total

1.  Development of a Terpene Feedstock-Based Oxidative Synthetic Approach to the Illicium Sesquiterpenes.

Authors:  Kevin Hung; Matthew L Condakes; Luiz F T Novaes; Stephen J Harwood; Takahiro Morikawa; Zhi Yang; Thomas J Maimone
Journal:  J Am Chem Soc       Date:  2019-02-11       Impact factor: 15.419

2.  Stereodivergent Attached-Ring Synthesis via Non-Covalent Interactions: A Short Formal Synthesis of Merrilactone A.

Authors:  Benjamin J Huffman; Tiffany Chu; Yusuke Hanaki; Jonathan J Wong; Shuming Chen; Kendall N Houk; Ryan A Shenvi
Journal:  Angew Chem Int Ed Engl       Date:  2021-12-09       Impact factor: 15.336

3.  Oxidative Entry into the Illicium Sesquiterpenes: Enantiospecific Synthesis of (+)-Pseudoanisatin.

Authors:  Kevin Hung; Matthew L Condakes; Takahiro Morikawa; Thomas J Maimone
Journal:  J Am Chem Soc       Date:  2016-12-16       Impact factor: 15.419

Review 4.  Total synthesis of complex terpenoids employing radical cascade processes.

Authors:  Kevin Hung; Xirui Hu; Thomas J Maimone
Journal:  Nat Prod Rep       Date:  2018-02-21       Impact factor: 13.423

5.  Synthetic, Mechanistic, and Biological Interrogation of Ginkgo biloba Chemical Space En Route to (-)-Bilobalide.

Authors:  Robert M Demoret; Meghan A Baker; Masaki Ohtawa; Shuming Chen; Ching Ching Lam; Sophia Khom; Marisa Roberto; Stefano Forli; Kendall N Houk; Ryan A Shenvi
Journal:  J Am Chem Soc       Date:  2020-10-16       Impact factor: 15.419

6.  One-Carbon Insertion and Polarity Inversion Enabled a Pyrrole Strategy to the Total Syntheses of Pyridine-Containing Lycopodium Alkaloids: Complanadine A and Lycodine.

Authors:  Donghui Ma; Brandon S Martin; Katelyn S Gallagher; Takeru Saito; Mingji Dai
Journal:  J Am Chem Soc       Date:  2021-09-27       Impact factor: 16.383

Review 7.  Change the channel: CysLoop receptor antagonists from nature.

Authors:  Guanghu Tong; Meghan A Baker; Ryan A Shenvi
Journal:  Pest Manag Sci       Date:  2020-11-22       Impact factor: 4.462

8.  Total Syntheses of (-)-Majucin and (-)-Jiadifenoxolane A, Complex Majucin-Type Illicium Sesquiterpenes.

Authors:  Matthew L Condakes; Kevin Hung; Stephen J Harwood; Thomas J Maimone
Journal:  J Am Chem Soc       Date:  2017-11-26       Impact factor: 15.419
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.