Literature DB >> 26888220

Oral manifestations of rheumatoid arthritis. A cross-sectional study of 73 patients.

Javier Silvestre-Rangil1,2, Leticia Bagán3, Francisco Javier Silvestre4, José Vicente Bagán5.   

Abstract

OBJECTIVE: A study is made of the main oral manifestations of patients with rheumatoid arthritis (RA), particularly salivary flow, and of its possible association to periodontal disease.
MATERIAL AND METHODS: A prospective comparative study was made of 146 patients (73 with RA and 73 controls), recording pocket depth, clinical attachment loss, bleeding index, plaque index, and the DMFT index to assess periodontal and dental alterations. Sialometric measurements were also made to determine resting, stimulated, and parotid salivary flow.
RESULTS: The patients with RA had greater periodontal pocket depths (with moderate depths in most cases), as well as greater attachment loss and more bacterial plaque. The resting whole saliva and stimulated parotid saliva rates were also clearly decreased in the RA group compared with the controls.
CONCLUSIONS: Patients with RA are more likely to present periodontal disease, poorer oral hygiene manifesting as an increased accumulation of bacterial plaque, and decreased salivary flow rates. CLINICAL RELEVANCE: Vulnerability to periodontitis is confirmed in one of the largest samples ever studied of patients with rheumatoid arthritis (RA). Also, there is evidence of hyposialia (decrease in salivary rate) in RA patients without Sjögren's syndrome.

Entities:  

Keywords:  Dental caries; Oral manifestations; Periodontal disease; Rheumatoid arthritis; Salivary flow

Mesh:

Year:  2016        PMID: 26888220     DOI: 10.1007/s00784-016-1745-z

Source DB:  PubMed          Journal:  Clin Oral Investig        ISSN: 1432-6981            Impact factor:   3.573


  28 in total

1.  PERIODONTAL DISEASE IN PREGNANCY. II. CORRELATION BETWEEN ORAL HYGIENE AND PERIODONTAL CONDTION.

Authors:  J SILNESS; H LOE
Journal:  Acta Odontol Scand       Date:  1964-02       Impact factor: 2.331

2.  Salivary secretion and connective tissue disease in man.

Authors:  R W Matthews; K D Bhoola; J J Rasker; M I Jayson
Journal:  Ann Rheum Dis       Date:  1985-01       Impact factor: 19.103

3.  Periodontal conditions in adults with rheumatoid arthritis.

Authors:  L Sjöström; L Laurell; A Hugoson; J P Håkansson
Journal:  Community Dent Oral Epidemiol       Date:  1989-10       Impact factor: 3.383

Review 4.  Periodontitis and rheumatoid arthritis: a review.

Authors:  P M Bartold; R I Marshall; D R Haynes
Journal:  J Periodontol       Date:  2005-11       Impact factor: 6.993

5.  Temporomandibular joint problems and periodontal condition in rheumatoid arthritis patients in relation to their rheumatologic status.

Authors:  Balkees Taha Garib; Sarhang S Qaradaxi
Journal:  J Oral Maxillofac Surg       Date:  2011-07-20       Impact factor: 1.895

6.  Relationship between rheumatoid arthritis and periodontitis.

Authors:  F B Mercado; R I Marshall; A C Klestov; P M Bartold
Journal:  J Periodontol       Date:  2001-06       Impact factor: 6.993

7.  Rheumatoid arthritis patients with xerostomia have reduced production of key salivary constituents.

Authors:  Anna Zalewska; Małgorzata Knaś; Napoleon Waszkiewicz; Danuta Waszkiel; Stanisław Sierakowski; Krzysztof Zwierz
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol       Date:  2013-01-09

8.  Detection of periodontal bacterial DNA in serum and synovial fluid in refractory rheumatoid arthritis patients.

Authors:  Rita E Martinez-Martinez; Carlos Abud-Mendoza; Nuria Patiño-Marin; Juan C Rizo-Rodríguez; James W Little; Juan Pablo Loyola-Rodríguez
Journal:  J Clin Periodontol       Date:  2009-12       Impact factor: 8.728

9.  Salivary gland involvement in rheumatoid arthritis and its relationship to induced oxidative stress.

Authors:  R M Nagler; F Salameh; A Z Reznick; V Livshits; A M Nahir
Journal:  Rheumatology (Oxford)       Date:  2003-07-30       Impact factor: 7.580

10.  The interleukin-1 and Fcgamma receptor gene polymorphisms in Japanese patients with rheumatoid arthritis and periodontitis.

Authors:  Tetsuo Kobayashi; Satoshi Ito; Takeshi Kuroda; Kouji Yamamoto; Noriko Sugita; Ichiei Narita; Takayuki Sumida; Fumitake Gejyo; Hiromasa Yoshie
Journal:  J Periodontol       Date:  2007-12       Impact factor: 6.993

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  9 in total

1.  Dietary fatty acids and the time elapsed from their intake are related to their composition in rat submandibular gland and salivary flow rates.

Authors:  Jorge Escandriolo Nackauzi; Gastón Repossi; Claudio Bernal; Adriana Actis; Raquel Gallará
Journal:  Clin Oral Investig       Date:  2020-05-21       Impact factor: 3.573

2.  Soluble neuropilin-1 in gingival crevicular fluid is associated with rheumatoid arthritis: An exploratory case-control study.

Authors:  Diego Prieto; Camila González; Laura Weber; Ornella Realini; Karina Pino-Lagos; Maria José Bendek; Ignacio Retamal; Víctor Beltrán; Juan Pablo Riedemann; Francisco Espinoza; Alejandra Chaparro
Journal:  J Oral Biol Craniofac Res       Date:  2021-02-22

3.  Salivary Gland Dysfunction, Protein Glycooxidation and Nitrosative Stress in Children with Chronic Kidney Disease.

Authors:  Mateusz Maciejczyk; Julita Szulimowska; Katarzyna Taranta-Janusz; Anna Wasilewska; Anna Zalewska
Journal:  J Clin Med       Date:  2020-04-29       Impact factor: 4.241

4.  Salivary Biomarkers and Oral Microbial Load in Relation to the Dental Status of Adults with Cystic Fibrosis.

Authors:  Tamara Pawlaczyk-Kamieńska; Maria Borysewicz-Lewicka; Halina Batura-Gabryel
Journal:  Microorganisms       Date:  2019-12-13

5.  Elevated serum TREM-1 is associated with periodontitis and disease activity in rheumatoid arthritis.

Authors:  Nevsun Inanc; Gonca Mumcu; Meryem Can; Meral Yay; Angelika Silbereisen; Daniel Manoil; Haner Direskeneli; Nagihan Bostanci
Journal:  Sci Rep       Date:  2021-02-03       Impact factor: 4.379

6.  Oral health-related quality of life and dental caries in rheumatoid arthritis patients: a cross-sectional observational study.

Authors:  Aida Mehdipour; Maryam Masoumi; Parisa Shajari; Mohammad Aghaali; Hoda Mousavi; Ali Saleh; Miad Ansarian
Journal:  J Med Life       Date:  2022-06

7.  Salivary citrullinated proteins in rheumatoid arthritis and associated periodontal disease.

Authors:  Ildikó Tar; Éva Csősz; Edit Végh; Karin Lundberg; Nastya Kharlamova; Boglárka Soós; Zoltán Szekanecz; Ildikó Márton
Journal:  Sci Rep       Date:  2021-06-29       Impact factor: 4.379

8.  Systemic treatment with resveratrol reduces the progression of experimental periodontitis and arthritis in rats.

Authors:  Mônica G Corrêa; Paula Rodrigues Pires; Fernanda Vieira Ribeiro; Suzana Peres Pimentel; Fabiano Ribeiro Cirano; Marcelo Henrique Napimoga; Marcio Z Casati; Renato Corrêa Viana Casarin
Journal:  PLoS One       Date:  2018-10-03       Impact factor: 3.240

9.  Rheumatoid arthritis is associated with early tooth loss: results from Korea National Health and Nutrition Examination Survey V to VI.

Authors:  Ji-Won Kim; Jun-Beom Park; Hyeon Woo Yim; Jennifer Lee; Seung-Ki Kwok; Ji Hyeon Ju; Wan-Uk Kim; Sung-Hwan Park
Journal:  Korean J Intern Med       Date:  2018-09-01       Impact factor: 2.884

  9 in total

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