Gang Lin1, Xiang-Jun Yang1. 1. Department of Cardiology, The First Affiliated Hospital of Soochow University Soochow 215006, China.
Abstract
OBJECTIVE: This study aims to observe the effects of circumferential pulmonary vein ablation (CPVA) and CPVA combined with complex fractionated atrial electro-gram (CPVA+CFAE) on morphology and function of left atrium in patients with atrial fibrillation (AF). METHODS: To evaluate the effects of CPVA and CPVA+CFAE on morphology and function of left atrium, the left atrial volume and late diastolic velocity peak (Va) were determined by tissue Doppler imaging before and after CPVA and CPVA+CFAE, respectively. RESULTS: There was no statistical difference in the left atrial volume before and after CPVA. However, Va was significantly higher after CPVA (P=0.001). There was no statistical difference in both the left atrial volume and Va before and after CPVA+CFAE. Va after ablation was significantly higher in CPVA group than in CPVA+CFAE group (P=0.031). CONCLUSION: The left atrial function was significantly improved after CPVA, but CPVA+CFAE failed to markedly improve the left atrial function. This suggests that excessive atrial substrate ablation may damage the left atrial function.
OBJECTIVE: This study aims to observe the effects of circumferential pulmonary vein ablation (CPVA) and CPVA combined with complex fractionated atrial electro-gram (CPVA+CFAE) on morphology and function of left atrium in patients with atrial fibrillation (AF). METHODS: To evaluate the effects of CPVA and CPVA+CFAE on morphology and function of left atrium, the left atrial volume and late diastolic velocity peak (Va) were determined by tissue Doppler imaging before and after CPVA and CPVA+CFAE, respectively. RESULTS: There was no statistical difference in the left atrial volume before and after CPVA. However, Va was significantly higher after CPVA (P=0.001). There was no statistical difference in both the left atrial volume and Va before and after CPVA+CFAE. Va after ablation was significantly higher in CPVA group than in CPVA+CFAE group (P=0.031). CONCLUSION: The left atrial function was significantly improved after CPVA, but CPVA+CFAE failed to markedly improve the left atrial function. This suggests that excessive atrial substrate ablation may damage the left atrial function.
Authors: Hirohiko Motoki; Arun Dahiya; Mandeep Bhargava; Oussama M Wazni; Walid I Saliba; Thomas H Marwick; Allan L Klein Journal: J Am Soc Echocardiogr Date: 2012-01-21 Impact factor: 5.251
Authors: Reinhold Weber; Jan Minners; Christian Restle; Gerd Buerkle; Franz-Josef Neumann; Dietrich Kalusche; Cornelius Keyl; Thomas Arentz Journal: J Cardiovasc Electrophysiol Date: 2007-12-20