Literature DB >> 26884394

Stomach development, stem cells and disease.

Tae-Hee Kim1, Ramesh A Shivdasani2.   

Abstract

The stomach, an organ derived from foregut endoderm, secretes acid and enzymes and plays a key role in digestion. During development, mesenchymal-epithelial interactions drive stomach specification, patterning, differentiation and growth through selected signaling pathways and transcription factors. After birth, the gastric epithelium is maintained by the activity of stem cells. Developmental signals are aberrantly activated and stem cell functions are disrupted in gastric cancer and other disorders. Therefore, a better understanding of stomach development and stem cells can inform approaches to treating these conditions. This Review highlights the molecular mechanisms of stomach development and discusses recent findings regarding stomach stem cells and organoid cultures, and their roles in investigating disease mechanisms.
© 2016. Published by The Company of Biologists Ltd.

Entities:  

Keywords:  Epithelial-mesenchymal interactions; Organogenesis; Transcriptional control of development

Mesh：

Year:  2016        PMID： 26884394      PMCID： PMC4760317          DOI： 10.1242/dev.124891

Source DB:  PubMed          Journal:  Development        ISSN： 0950-1991            Impact factor:   6.868


  139 in total

1.  Requirement of the tissue-restricted homeodomain transcription factor Nkx6.3 in differentiation of gastrin-producing G cells in the stomach antrum.

Authors:  Michael Y Choi; Anthony I Romer; Yang Wang; Melissa P Wu; Susumu Ito; Andrew B Leiter; Ramesh A Shivdasani
Journal:  Mol Cell Biol       Date:  2008-03-17       Impact factor: 4.272

2.  Mechanisms of field cancerization in the human stomach: the expansion and spread of mutated gastric stem cells.

Authors:  Stuart A C McDonald; Laura C Greaves; Lydia Gutierrez-Gonzalez; Manuel Rodriguez-Justo; Maesha Deheragoda; Simon J Leedham; Robert W Taylor; Chung Yin Lee; Sean L Preston; Matthew Lovell; Toby Hunt; George Elia; Dahmane Oukrif; Rebecca Harrison; Marco R Novelli; Ian Mitchell; David L Stoker; Douglass M Turnbull; Janusz A Z Jankowski; Nicholas A Wright
Journal:  Gastroenterology       Date:  2007-11-28       Impact factor: 22.682

3.  Bone morphogenetic protein signaling suppresses tumorigenesis at gastric epithelial transition zones in mice.

Authors:  Sylvia A Bleuming; Xi C He; Liudmila L Kodach; James C Hardwick; Frieda A Koopman; Fiebo J Ten Kate; Sander J H van Deventer; Daniel W Hommes; Maikel P Peppelenbosch; G Johan Offerhaus; Linheng Li; Gijs R van den Brink
Journal:  Cancer Res       Date:  2007-09-01       Impact factor: 12.701

4.  Emergence of spasmolytic polypeptide-expressing metaplasia in Mongolian gerbils infected with Helicobacter pylori.

Authors:  Nao Yoshizawa; Yoshiharu Takenaka; Hirokazu Yamaguchi; Tsukamoto Tetsuya; Harunari Tanaka; Masae Tatematsu; Sachiyo Nomura; James R Goldenring; Michio Kaminishi
Journal:  Lab Invest       Date:  2007-12       Impact factor: 5.662

5.  Mash1 is required for neuroendocrine cell development in the glandular stomach.

Authors:  Hiroshi Kokubu; Toshiyuki Ohtsuka; Ryoichiro Kageyama
Journal:  Genes Cells       Date:  2008-01       Impact factor: 1.891

6.  Transcription factor foxq1 controls mucin gene expression and granule content in mouse stomach surface mucous cells.

Authors:  Michael P Verzi; Abdul H Khan; Susumu Ito; Ramesh A Shivdasani
Journal:  Gastroenterology       Date:  2008-04-22       Impact factor: 22.682

7.  Identification of stem cells in small intestine and colon by marker gene Lgr5.

Authors:  Nick Barker; Johan H van Es; Jeroen Kuipers; Pekka Kujala; Maaike van den Born; Miranda Cozijnsen; Andrea Haegebarth; Jeroen Korving; Harry Begthel; Peter J Peters; Hans Clevers
Journal:  Nature       Date:  2007-10-14       Impact factor: 49.962

8.  Prospective identification of a multilineage progenitor in murine stomach epithelium.

Authors:  Xiaotan T Qiao; Joshua W Ziel; Wendy McKimpson; Blair B Madison; Andrea Todisco; Juanita L Merchant; Linda C Samuelson; Deborah L Gumucio
Journal:  Gastroenterology       Date:  2007-12       Impact factor: 22.682

9.  Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen.

Authors:  Byeong-Moo Kim; Isabelle Miletich; Junhao Mao; Andrew P McMahon; Paul A Sharpe; Ramesh A Shivdasani
Journal:  Development       Date:  2007-09-12       Impact factor: 6.868

10.  SOX2 is frequently downregulated in gastric cancers and inhibits cell growth through cell-cycle arrest and apoptosis.

Authors:  T Otsubo; Y Akiyama; K Yanagihara; Y Yuasa
Journal:  Br J Cancer       Date:  2008-02-12       Impact factor: 7.640
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  51 in total

1.  Multiple roles of epithelial heparan sulfate in stomach morphogenesis.

Authors:  Meina Huang; Hua He; Tatyana Belenkaya; Xinhua Lin
Journal:  J Cell Sci       Date:  2018-05-29       Impact factor: 5.285

2.  A gene regulatory network explains RET-EDNRB epistasis in Hirschsprung disease.

Authors:  Sumantra Chatterjee; Aravinda Chakravarti
Journal:  Hum Mol Genet       Date:  2019-09-15       Impact factor: 6.150

Review 3.  Acid and the basis for cellular plasticity and reprogramming in gastric repair and cancer.

Authors:  José B Sáenz; Jason C Mills
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2018-02-21       Impact factor: 46.802

4.  Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells.

Authors:  Alexandra K Eicher; Daniel O Kechele; Nambirajan Sundaram; H Matthew Berns; Holly M Poling; Lauren E Haines; J Guillermo Sanchez; Keishi Kishimoto; Mansa Krishnamurthy; Lu Han; Aaron M Zorn; Michael A Helmrath; James M Wells
Journal:  Cell Stem Cell       Date:  2021-12-01       Impact factor: 24.633

5.  Defining the Teratoma as a Model for Multi-lineage Human Development.

Authors:  Daniella McDonald; Yan Wu; Amir Dailamy; Justin Tat; Udit Parekh; Dongxin Zhao; Michael Hu; Ann Tipps; Kun Zhang; Prashant Mali
Journal:  Cell       Date:  2020-11-04       Impact factor: 41.582

Review 6.  Tuft Cells-Systemically Dispersed Sensory Epithelia Integrating Immune and Neural Circuitry.

Authors:  Claire E O'Leary; Christoph Schneider; Richard M Locksley
Journal:  Annu Rev Immunol       Date:  2018-10-31       Impact factor: 28.527

7.  MicroRNA-421 promotes the proliferation and metastasis of gastric cancer cells by targeting claudin-11.

Authors:  Peng Yang; Mei Zhang; Xiting Liu; Huayun Pu
Journal:  Exp Ther Med       Date:  2017-07-17       Impact factor: 2.447

8.  Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells.

Authors:  Seungmin Han; Juergen Fink; David J Jörg; Eunmin Lee; Min Kyu Yum; Lemonia Chatzeli; Sebastian R Merker; Manon Josserand; Teodora Trendafilova; Amanda Andersson-Rolf; Catherine Dabrowska; Hyunki Kim; Ronald Naumann; Ji-Hyun Lee; Nobuo Sasaki; Richard Lester Mort; Onur Basak; Hans Clevers; Daniel E Stange; Anna Philpott; Jong Kyoung Kim; Benjamin D Simons; Bon-Kyoung Koo
Journal:  Cell Stem Cell       Date:  2019-08-15       Impact factor: 24.633

Review 9.  Winding back Wnt signalling: potential therapeutic targets for treating gastric cancers.

Authors:  Dustin J Flanagan; Elizabeth Vincan; Toby J Phesse
Journal:  Br J Pharmacol       Date:  2017-07-05       Impact factor: 8.739

Review 10.  The pediatric stomach - congenital abnormalities.

Authors:  Michael S Furman; Susan A Connolly; Stephen D Brown; Michael J Callahan
Journal:  Pediatr Radiol       Date:  2021-08-05
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