| Literature DB >> 26883705 |
Andrew P Norgan1, Jarred M Freese2, Patricia M Tuin2, Scott A Cunningham3, Patricio R Jeraldo4, Robin Patel5.
Abstract
Resistance to carbapenems in Enterobacteriaceae is a clinical problem of growing significance. Difficulty in treating multidrug-resistant Gram-negative organisms with conventional antibiotics has led to a renewed and increasing use of polymyxin compounds, such as colistin. Here, we report the isolation of carbapenem- and colistin-resistant Enterobacter cloacae from a polymicrobial lower extremity wound in an ambulatory patient. Whole-genome sequencing demonstrated the presence of chromosomal blaIMI-1 and blaAmpC, as well as numerous efflux pump genes.Entities:
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Year: 2016 PMID: 26883705 PMCID: PMC4862446 DOI: 10.1128/AAC.03055-15
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191