Literature DB >> 26882656

Cytochalasans and Sesquiterpenes from Eutypella scoparia 1-15.

Shuang Qi, Yue Wang, Zhonghui Zheng, Qingyan Xu, Xianming Deng.   

Abstract

Three new compounds, an open-chain cytochalasan scoparasin C (1), a pyrichalasan scoparasin D (2), and a β-eudesmol type sesquiterpene scopararane C (5), along with three known compounds (3, 4 and 6), were isolated from the marine fungus Eutypella scoparia 1-15. Their structures were determined on the basis of comprehensive NMR and MS analysis. Compound 2 exhibited potent cytotoxicities with very low IC50 values against several cancer cell lines, including A375, A549, HepG2 and MCF-7.

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Year:  2015        PMID: 26882656

Source DB:  PubMed          Journal:  Nat Prod Commun        ISSN: 1555-9475            Impact factor:   0.986


  3 in total

1.  New 12,8-Eudesmanolides from Eutypella sp. 1-15.

Authors:  Yuezhou Wang; Yue Wang; An-An Wu; Lei Zhang; Zhiyu Hu; Huiying Huang; Qingyan Xu; Xianming Deng
Journal:  J Antibiot (Tokyo)       Date:  2017-07-19       Impact factor: 2.649

2.  Progress in the Chemistry of Cytochalasans.

Authors:  Hucheng Zhu; Chunmei Chen; Qingyi Tong; Yuan Zhou; Ying Ye; Lianghu Gu; Yonghui Zhang
Journal:  Prog Chem Org Nat Prod       Date:  2021

3.  A four-protein metabolon assembled by a small peptide protein creates the pentacyclic carbonate ring of aldgamycins.

Authors:  Qiaozhen Wang; Xiaolong Tang; Ping Dai; Chuanxi Wang; Weiyang Zhang; Guodong Chen; Kui Hong; Dan Hu; Hao Gao; Xinsheng Yao
Journal:  Acta Pharm Sin B       Date:  2020-07-30       Impact factor: 11.413

  3 in total

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