Literature DB >> 26879987

3-Acylated tetramic and tetronic acids as natural metal binders: myth or reality?

Mehdi Zaghouani1, Bastien Nay.   

Abstract

Covering: up to 20153-Acylated tetramic and tetronic acids are characterized by a low pKa and are likely to be deprotonated under physiological conditions. In addition, their structure makes them excellent chelators of metallic cations. We will discuss the significance of these chemical properties with regard to the biological properties and mechanisms of action of these compounds, highlighting the importance of considering them as salts or chelates for biological purposes, rather than acids.

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Year:  2016        PMID： 26879987     DOI： 10.1039/c5np00144g

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  8 in total

1.  Functionalised bicyclic tetramates derived from cysteine as antibacterial agents.

Authors:  Tharindi D Panduwawala; Sarosh Iqbal; Amber L Thompson; Miroslav Genov; Alexander Pretsch; Dagmar Pretsch; Shuang Liu; Richard H Ebright; Alison Howells; Anthony Maxwell; Mark G Moloney
Journal:  Org Biomol Chem       Date:  2019-06-05       Impact factor: 3.876

2.  Genome-Mined Diels-Alderase Catalyzes Formation of the cis-Octahydrodecalins of Varicidin A and B.

Authors:  Dan Tan; Cooper S Jamieson; Masao Ohashi; Man-Cheng Tang; K N Houk; Yi Tang
Journal:  J Am Chem Soc       Date:  2019-01-08       Impact factor: 15.419

3.  X-Ray Crystallographic Analysis, EPR Studies, and Computational Calculations of a Cu(II) Tetramic Acid Complex.

Authors:  Dimitrios Matiadis; Dimitrios Tsironis; Valentina Stefanou; Olga Igglessi-Markopoulou; Vickie McKee; Yiannis Sanakis; Katerina N Lazarou; Athanassios Chrissanthopoulos; Spyros N Yannopoulos; John M Markopoulos
Journal:  Bioinorg Chem Appl       Date:  2017-02-19       Impact factor: 7.778

4.  Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer's Disease Agents.

Authors:  Viviana Poliseno; Sílvia Chaves; Leonardo Brunetti; Fulvio Loiodice; Antonio Carrieri; Antonio Laghezza; Paolo Tortorella; João D Magalhães; Sandra M Cardoso; M Amélia Santos; Luca Piemontese
Journal:  Biomolecules       Date:  2021-01-15

5.  An exceptionally stable and widespread hydrated amorphous calcium carbonate precipitated by the dog vomit slime mold Fuligo septica (Myxogastria).

Authors:  Laurence A J Garvie; Péter Németh; László Trif
Journal:  Sci Rep       Date:  2022-03-07       Impact factor: 4.379

6.  Mediation of metal chelation in cysteine-derived tetramate systems.

Authors:  Ruirui Zhang; Miroslav Genov; Alexander Pretsch; Dagmar Pretsch; Mark G Moloney
Journal:  Chem Sci       Date:  2021-12-02       Impact factor: 9.825

Review 7.  Chelation in Antibacterial Drugs: From Nitroxoline to Cefiderocol and Beyond.

Authors:  Davorka Repac Antić; Marijo Parčina; Ivana Gobin; Mirna Petković Didović
Journal:  Antibiotics (Basel)       Date:  2022-08-15

8.  Bivalent Metal-Chelating Properties of Harzianic Acid Produced by Trichoderma pleuroticola Associated to the Gastropod Melarhaphe neritoides.

Authors:  Gaetano De Tommaso; Maria Michela Salvatore; Rosario Nicoletti; Marina DellaGreca; Francesco Vinale; Assunta Bottiglieri; Alessia Staropoli; Francesco Salvatore; Matteo Lorito; Mauro Iuliano; Anna Andolfi
Journal:  Molecules       Date:  2020-05-04       Impact factor: 4.411
  8 in total

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