Literature DB >> 26877576

Non-mydriatic confocal retinal imaging using a digital light projector.

Matthew S Muller1, Jason J Green2, Karthikeyan Baskaran2, Allen W Ingling1, Jeffrey L Clendenon1, Thomas J Gast3, Ann E Elsner3.   

Abstract

A digital light projector is implemented as an integrated illumination source and scanning element in a confocal non-mydriatic retinal camera, the Digital Light Ophthalmoscope (DLO). To simulate scanning, a series of illumination lines are rapidly projected on the retina. The backscattered light is imaged onto a 2-dimensional rolling shutter CMOS sensor. By temporally and spatially overlapping the illumination lines with the rolling shutter, confocal imaging is achieved. This approach enables a low cost, flexible, and robust design with a small footprint. The 3rd generation DLO technical design is presented, using a DLP LightCrafter 4500 and USB3.0 CMOS sensor. Specific improvements over previous work include the use of yellow illumination, filtered from the broad green LED spectrum, to obtain strong blood absorption and high contrast images while reducing pupil constriction and patient discomfort.

Entities:  

Keywords:  CMOS; DLP; Digital Light Ophthalmoscope; LightCrafter; confocal imaging; imaging; retina; rolling shutter

Year:  2015        PMID: 26877576      PMCID: PMC4749182          DOI: 10.1117/12.2077704

Source DB:  PubMed          Journal:  Proc SPIE Int Soc Opt Eng        ISSN: 0277-786X


  4 in total

1.  Infrared imaging of sub-retinal structures in the human ocular fundus.

Authors:  A E Elsner; S A Burns; J J Weiter; F C Delori
Journal:  Vision Res       Date:  1996-01       Impact factor: 1.886

2.  Laser applications and system considerations in ocular imaging.

Authors:  Ann E Elsner; Matthew S Muller
Journal:  Laser Photon Rev       Date:  2008-10-01       Impact factor: 13.138

3.  Non-Mydriatic Confocal Retinal Imaging Using a Digital Light Projector.

Authors:  Matthew S Muller; Ann E Elsner; Glen Y Ozawa
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2013-03-26

4.  A Pico Projector Source for Confocal Fluorescence and Ophthalmic Imaging.

Authors:  Matthew S Muller
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2012-09-02
  4 in total
  6 in total

1.  Digital micromirror device based ophthalmoscope with concentric circle scanning.

Authors:  Mathi Damodaran; Kari V Vienola; Boy Braaf; Koenraad A Vermeer; Johannes F de Boer
Journal:  Biomed Opt Express       Date:  2017-04-28       Impact factor: 3.732

2.  Improving nuclear morphometry imaging with real-time and low-cost line-scanning confocal microendoscope.

Authors:  Yubo Tang; Alex Kortum; Imran Vohra; Mohamed Othman; Sadhna Dhingra; Nabil Mansour; Jennifer Carns; Sharmila Anandasabapathy; Rebecca Richards-Kortum
Journal:  Opt Lett       Date:  2019-02-01       Impact factor: 3.776

3.  Confocal Retinal Imaging Using a Digital Light Projector with a Near Infrared VCSEL Source.

Authors:  Matthew S Muller; Ann E Elsner
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2018-02

4.  Adaptive optics parallel near-confocal scanning ophthalmoscopy.

Authors:  Jing Lu; Boyu Gu; Xiaolin Wang; Yuhua Zhang
Journal:  Opt Lett       Date:  2016-08-15       Impact factor: 3.776

5.  Line-scanning confocal microendoscope for nuclear morphometry imaging.

Authors:  Yubo Tang; Jennifer Carns; Rebecca R Richards-Kortum
Journal:  J Biomed Opt       Date:  2017-11       Impact factor: 3.170

Review 6.  Cones in ageing and harsh environments: the neural economy hypothesis.

Authors:  Ann E Elsner; Joel A Papay; Kirby D Johnston; Lucie Sawides; Alberto de Castro; Brett J King; Durand W Jones; Christopher A Clark; Thomas J Gast; Stephen A Burns
Journal:  Ophthalmic Physiol Opt       Date:  2020-02-04       Impact factor: 3.117

  6 in total

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