Literature DB >> 26876936

Stem cell secretome-rich nanoclay hydrogel: a dual action therapy for cardiovascular regeneration.

Renae Waters1, Settimio Pacelli1, Ryan Maloney1, Indrani Medhi2, Rafeeq P H Ahmed3, Arghya Paul1.   

Abstract

A nanocomposite hydrogel with photocrosslinkable micro-porous networks and a nanoclay component was successfully prepared to control the release of growth factor-rich stem cell secretome. The proven pro-angiogenic and cardioprotective potential of this new bioactive system provides a valuable therapeutic platform for cardiac tissue repair and regeneration.

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Year:  2016        PMID： 26876936      PMCID： PMC4863075          DOI： 10.1039/c5nr07806g

Source DB:  PubMed          Journal:  Nanoscale        ISSN： 2040-3364            Impact factor:   7.790


  25 in total

1.  Conditioned medium from hypoxic cells protects cardiomyocytes against ischemia.

Authors:  B Chanyshev; A Shainberg; A Isak; Y Chepurko; E Porat; E Hochhauser
Journal:  Mol Cell Biochem       Date:  2011-12-08       Impact factor: 3.396

2.  Soluble factors from multipotent mesenchymal stromal cells have antinecrotic effect on cardiomyocytes in vitro and improve cardiac function in infarcted rat hearts.

Authors:  P Fidelis-de-Oliveira; J P S Werneck-de-Castro; V Pinho-Ribeiro; B C M Shalom; J H Nascimento-Silva; R H Costa e Souza; I S Cruz; R R Rangel; R C S Goldenberg; A C Campos-de-Carvalho
Journal:  Cell Transplant       Date:  2012-02-02       Impact factor: 4.064

Review 3.  Nanocomposite Hydrogels and Their Applications in Drug Delivery and Tissue Engineering.

Authors:  Fangfang Song; Xiaoqiong Li; Qun Wang; Liqiong Liao; Chao Zhang
Journal:  J Biomed Nanotechnol       Date:  2015-01       Impact factor: 4.099

4.  Promises, facts and challenges for carbon nanotubes in imaging and therapeutics.

Authors:  K Kostarelos; A Bianco; M Prato
Journal:  Nat Nanotechnol       Date:  2009-09-27       Impact factor: 39.213

5.  Activation of diverse signaling pathways by ex-vivo delivery of multiple cytokines for myocardial repair.

Authors:  Mikhail Konoplyannikov; Khawaja Husnain Haider; Vien Khach Lai; Rafeeq P H Ahmed; Shujia Jiang; Muhammad Ashraf
Journal:  Stem Cells Dev       Date:  2012-10-05       Impact factor: 3.272

6.  Dual growth factor delivery from bilayered, biodegradable hydrogel composites for spatially-guided osteochondral tissue repair.

Authors:  Steven Lu; Johnny Lam; Jordan E Trachtenberg; Esther J Lee; Hajar Seyednejad; Jeroen J J P van den Beucken; Yasuhiko Tabata; Mark E Wong; John A Jansen; Antonios G Mikos; F Kurtis Kasper
Journal:  Biomaterials       Date:  2014-07-18       Impact factor: 12.479

7.  Dual-delivery of VEGF and PDGF by double-layered electrospun membranes for blood vessel regeneration.

Authors:  Hong Zhang; Xiaoling Jia; Fengxuan Han; Jin Zhao; Yunhui Zhao; Yubo Fan; Xiaoyan Yuan
Journal:  Biomaterials       Date:  2013-01-03       Impact factor: 12.479

8.  Enhancing cancer targeting and anticancer activity by a stimulus-sensitive multifunctional polymer-drug conjugate.

Authors:  Ying Tu; Lin Zhu
Journal:  J Control Release       Date:  2015-06-22       Impact factor: 9.776

9.  Fullerene C₆₀ as a multifunctional system for drug and gene delivery.

Authors:  Alejandro Montellano; Tatiana Da Ros; Alberto Bianco; Maurizio Prato
Journal:  Nanoscale       Date:  2011-09-07       Impact factor: 7.790

10.  Surface selective binding of nanoclay particles to polyampholyte protein chains.

Authors:  Nisha Pawar; H B Bohidar
Journal:  J Chem Phys       Date:  2009-07-28       Impact factor: 3.488
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  21 in total

Review 1.  Strategies to develop endogenous stem cell-recruiting bioactive materials for tissue repair and regeneration.

Authors:  Settimio Pacelli; Sayantani Basu; Jonathan Whitlow; Aparna Chakravarti; Francisca Acosta; Arushi Varshney; Saman Modaresi; Cory Berkland; Arghya Paul
Journal:  Adv Drug Deliv Rev       Date:  2017-07-19       Impact factor: 15.470

Review 2.  2D Nanoclay for Biomedical Applications: Regenerative Medicine, Therapeutic Delivery, and Additive Manufacturing.

Authors:  Akhilesh K Gaharwar; Lauren M Cross; Charles W Peak; Karli Gold; James K Carrow; Anna Brokesh; Kanwar Abhay Singh
Journal:  Adv Mater       Date:  2019-04-03       Impact factor: 30.849

3.  Nanodiamond-based injectable hydrogel for sustained growth factor release: Preparation, characterization and in vitro analysis.

Authors:  Settimio Pacelli; Francisca Acosta; Aparna R Chakravarti; Saheli G Samanta; Jonathan Whitlow; Saman Modaresi; Rafeeq P H Ahmed; Johnson Rajasingh; Arghya Paul
Journal:  Acta Biomater       Date:  2017-05-19       Impact factor: 8.947

4.  Development of MicroRNA-146a-Enriched Stem Cell Secretome for Wound-Healing Applications.

Authors:  Renae Waters; Siddharth Subham; Settimio Pacelli; Saman Modaresi; Aparna R Chakravarti; Arghya Paul
Journal:  Mol Pharm       Date:  2019-08-26       Impact factor: 4.939

5.  Biomaterials functionalized with MSC secreted extracellular vesicles and soluble factors for tissue regeneration.

Authors:  Meadhbh Á Brennan; Pierre Layrolle; David J Mooney
Journal:  Adv Funct Mater       Date:  2020-03-11       Impact factor: 18.808

6.  Polymeric Nanohybrids as a New Class of Therapeutic Biotransporters.

Authors:  Jonathan Whitlow; Settimio Pacelli; Arghya Paul
Journal:  Macromol Chem Phys       Date:  2016-04-26       Impact factor: 2.527

7.  Deciphering the role of substrate stiffness in enhancing the internalization efficiency of plasmid DNA in stem cells using lipid-based nanocarriers.

Authors:  Saman Modaresi; Settimio Pacelli; Jonathan Whitlow; Arghya Paul
Journal:  Nanoscale       Date:  2018-05-17       Impact factor: 7.790

8.  MicroRNA-1825 induces proliferation of adult cardiomyocytes and promotes cardiac regeneration post ischemic injury.

Authors:  Raghav Pandey; Sebastian Velasquez; Shazia Durrani; Min Jiang; Michelle Neiman; Jeffrey S Crocker; Joshua B Benoit; Jack Rubinstein; Arghya Paul; Rafeeq Ph Ahmed
Journal:  Am J Transl Res       Date:  2017-06-15       Impact factor: 4.060

9.  Harnessing the Noncovalent Interactions of DNA Backbone with 2D Silicate Nanodisks To Fabricate Injectable Therapeutic Hydrogels.

Authors:  Sayantani Basu; Settimio Pacelli; Yi Feng; Qinghua Lu; Jinxi Wang; Arghya Paul
Journal:  ACS Nano       Date:  2018-09-18       Impact factor: 15.881

10.  Pre-Conditioning Stem Cells in a Biomimetic Environment for Enhanced Cardiac Tissue Repair: In Vitro and In Vivo Analysis.

Authors:  Aparna R Chakravarti; Settimio Pacelli; Perwez Alam; Samik Bagchi; Saman Modaresi; Andras Czirok; Rafeeq P H Ahmed; Arghya Paul
Journal:  Cell Mol Bioeng       Date:  2018-07-26       Impact factor: 2.321
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