Literature DB >> 26870326

Efficacy of traditional Chinese medicine in treating cancer.

Jiao Nie1, Changlin Zhao2, L I Deng1, Jia Chen1, Bin Yu3, Xianlin Wu4, Peng Pang1, Xiaoyin Chen1.   

Abstract

The morbidity associated with cancer has rapidly increased in recent years, and in the previous 5 years has had a tendency to be the leading cause of fatality compared with cardiovascular disease. Therefore, effective measures are required with an aim to reduce the incidence. Based on the results of clinical investigation, a multidisciplinary treatment strategy for cancer, which includes radiotherapy, chemotherapy, surgery, targeted therapy and immunotherapy, are prominently used in clinical practice. However, the therapies are insufficient due to multidrug resistance, adverse effects and the presence of the root of the cancer. Therefore, there is a necessity to develop more effective or adjunctive therapies for cancer prevention and treatment. Cancer is now widely recognized as a systemic humoral disease. Similarly, the function of herbal drugs is to modulate the whole body system in a more holistic way. Recently, herbal drugs have been applied to one of the efficient approaches for cancer therapy. Furthermore, there is evidence that various herbal medicines have been proven to be useful and effective in sensitizing the conventional agents against the various factors at the cellular and molecular levels that are associated with the occurrence of cancer and in prolonging survival time, alleviating side effects of chemotherapy and radiotherapy and improving the quality of life in cancer patients.

Entities:  

Keywords:  cancer; cellular and molecular level; herbal medicines; quality of life; side effects; survival time

Year:  2015        PMID: 26870326      PMCID: PMC4726876          DOI: 10.3892/br.2015.537

Source DB:  PubMed          Journal:  Biomed Rep        ISSN: 2049-9434


  72 in total

1.  Mechanism of action of herbal supplement PC-SPES: elucidation of effects of individual herbs of PC-SPES on proliferation and prostate specific gene expression in androgen-dependent LNCaP cells.

Authors:  Tze-Chen Hsieh; Joseph M Wu
Journal:  Int J Oncol       Date:  2002-03       Impact factor: 5.650

Review 2.  Cancer prevention and therapy through the modulation of the tumor microenvironment.

Authors:  Stephanie C Casey; Amedeo Amedei; Katia Aquilano; Asfar S Azmi; Fabian Benencia; Dipita Bhakta; Alan E Bilsland; Chandra S Boosani; Sophie Chen; Maria Rosa Ciriolo; Sarah Crawford; Hiromasa Fujii; Alexandros G Georgakilas; Gunjan Guha; Dorota Halicka; William G Helferich; Petr Heneberg; Kanya Honoki; W Nicol Keith; Sid P Kerkar; Sulma I Mohammed; Elena Niccolai; Somaira Nowsheen; H P Vasantha Rupasinghe; Abbas Samadi; Neetu Singh; Wamidh H Talib; Vasundara Venkateswaran; Richard L Whelan; Xujuan Yang; Dean W Felsher
Journal:  Semin Cancer Biol       Date:  2015-04-10       Impact factor: 15.707

3.  Oxymatrine targets EGFR(p-Tyr845) and inhibits EGFR-related signaling pathways to suppress the proliferation and invasion of gastric cancer cells.

Authors:  Bingyu Guo; Tingting Zhang; Jingyuan Su; Kaiwen Wang; Xiaoming Li
Journal:  Cancer Chemother Pharmacol       Date:  2014-12-20       Impact factor: 3.333

4.  Improving cachectic symptoms and immune strength of tumour-bearing mice in chemotherapy by a combination of Scutellaria baicalensis and Qing-Shu-Yi-Qi-Tang.

Authors:  Hang Wang; Yi-Lin Chan; Tsung-Lin Li; Chang-Jer Wu
Journal:  Eur J Cancer       Date:  2011-07-23       Impact factor: 9.162

5.  Active Chinese mistletoe lectin-55 enhances colon cancer surveillance through regulating innate and adaptive immune responses.

Authors:  Yan-Hui Ma; Wei-Zhi Cheng; Fang Gong; An-Lun Ma; Qi-Wen Yu; Ji-Ying Zhang; Chao-Ying Hu; Xue-Hua Chen; Dong-Qing Zhang
Journal:  World J Gastroenterol       Date:  2008-09-14       Impact factor: 5.742

Review 6.  Targeting multidrug resistance in cancer.

Authors:  Gergely Szakács; Jill K Paterson; Joseph A Ludwig; Catherine Booth-Genthe; Michael M Gottesman
Journal:  Nat Rev Drug Discov       Date:  2006-03       Impact factor: 84.694

Review 7.  The efficacy of Chinese herbal medicine as an adjunctive therapy for advanced non-small cell lung cancer: a systematic review and meta-analysis.

Authors:  Shi Guang Li; Hai Yong Chen; Chen Sheng Ou-Yang; Xi-Xin Wang; Zhen-Jiang Yang; Yao Tong; William C S Cho
Journal:  PLoS One       Date:  2013-02-28       Impact factor: 3.240

8.  Oxymatrine induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome c.

Authors:  Qi Ling; Xiao Xu; Xuyong Wei; Weibing Wang; Bin Zhou; Bei Wang; Shusen Zheng
Journal:  J Exp Clin Cancer Res       Date:  2011-06-29

9.  Regulatory effect of astragalus polysaccharides on intestinal intraepithelial γδT cells of tumor bearing mice.

Authors:  Shuyu Sun; Kang Zheng; Hongyan Zhao; Cheng Lu; Biao Liu; Changyuan Yu; Ge Zhang; Zhaoxiang Bian; Aiping Lu; Xiaojuan He
Journal:  Molecules       Date:  2014-09-23       Impact factor: 4.411

10.  Comparison of efficacy and toxicity of traditional Chinese medicine (TCM) herbal mixture LQ and conventional chemotherapy on lung cancer metastasis and survival in mouse models.

Authors:  Lei Zhang; Chengyu Wu; Yong Zhang; Fang Liu; Xiaoen Wang; Ming Zhao; Robert M Hoffman
Journal:  PLoS One       Date:  2014-10-06       Impact factor: 3.240

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  27 in total

1.  SH003 enhances paclitaxel chemosensitivity in MCF-7/PAX breast cancer cells through inhibition of MDR1 activity.

Authors:  Hyeong Sim Choi; Sung-Gook Cho; Min Kyoung Kim; Hee Jae Lee; Seung Hee Moon; Hee Jae Jang; Seong-Gyu Ko
Journal:  Mol Cell Biochem       Date:  2016-11-16       Impact factor: 3.396

2.  Mechanism of Hedyotis Diffusa in the Treatment of Cervical Cancer.

Authors:  Kai Qian; Dan Fu; Baorui Jiang; Yue Wang; Fei Tian; Li Song; Lei Li
Journal:  Front Pharmacol       Date:  2021-12-15       Impact factor: 5.810

3.  Pine needle oil induces G2/M arrest of HepG2 cells by activating the ATM pathway.

Authors:  Bing Qiu; Wei Jiang; Wenliang Qiu; Wenling Mu; Yujing Qin; Yongcui Zhu; Jianying Zhang; Qingyi Wang; Dongjie Liu; Zhangyi Qu
Journal:  Exp Ther Med       Date:  2017-12-15       Impact factor: 2.447

4.  Efficacy of Topical Compound Danxiong Granules for Treatment of Dermatologic Toxicities Induced by Targeted Anticancer Therapy: A Randomized, Double-Blind, Placebo-Controlled Trial.

Authors:  Aiping Tian; Aiping Zhou; Xinyu Bi; Shangying Hu; Zhichao Jiang; Wen Zhang; Zhen Huang; Hongzhe Shi; Boyan Yang; Wei Chen
Journal:  Evid Based Complement Alternat Med       Date:  2017-08-06       Impact factor: 2.629

5.  Predicted molecular targets and pathways for germacrone, curdione, and furanodiene in the treatment of breast cancer using a bioinformatics approach.

Authors:  Qi Kong; Yong Ma; Jie Yu; Xiuping Chen
Journal:  Sci Rep       Date:  2017-11-14       Impact factor: 4.379

Review 6.  Anti-tumor effects of the American cockroach, Periplaneta americana.

Authors:  Yanan Zhao; Ailin Yang; Pengfei Tu; Zhongdong Hu
Journal:  Chin Med       Date:  2017-09-12       Impact factor: 5.455

Review 7.  Role of Autophagy and Apoptosis in Non-Small-Cell Lung Cancer.

Authors:  Guangbo Liu; Fen Pei; Fengqing Yang; Lingxiao Li; Amit Dipak Amin; Songnian Liu; J Ross Buchan; William C Cho
Journal:  Int J Mol Sci       Date:  2017-02-10       Impact factor: 5.923

8.  TAM Infiltration Differences in "Tumor-First" and " ZHENG-First" Models and the Underlying Inflammatory Molecular Mechanism in Pancreatic Cancer.

Authors:  Feng-Jiao Wang; Peng Wang; Lian-Yu Chen; Ya-Wen Geng; Hao Chen; Zhi-Qiang Meng; Lu-Ming Liu; Zhen Chen
Journal:  Integr Cancer Ther       Date:  2018-04-22       Impact factor: 3.279

9.  End-to-End Models to Imitate Traditional Chinese Medicine Syndrome Differentiation in Lung Cancer Diagnosis: Model Development and Validation.

Authors:  Ziqing Liu; Haiyang He; Shixing Yan; Yong Wang; Tao Yang; Guo-Zheng Li
Journal:  JMIR Med Inform       Date:  2020-06-16

10.  A clinical study of Yiqi Huayu Jiedu decoction reducing the risk of postoperative gastric cancer recurrence and metastasis: Study protocol for a randomized controlled trail.

Authors:  Yue Hu; Xiaoting Pan; Mengjun Nie; Yuanjie Liu; Xi Zou; Shenlin Liu; Qin Liu; Ruiping Wang; Li Zhang
Journal:  Medicine (Baltimore)       Date:  2020-08-14       Impact factor: 1.817

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