Sonali Rajan1, Tom Weishaar1, Bryan Keller2. 1. 1Department of Health and Behavior Studies,Teachers College,Columbia University,525 West 120th Street,New York,NY 10027,USA. 2. 2Department of Human Development,Teachers College,Columbia University,New York,NY,USA.
Abstract
OBJECTIVE: Current US dietary recommendations for vitamin D vary by age. Recent research suggests that body weight and skin colour are also major determinants of vitamin D status. The objective of the present epidemiological investigation was to clarify the role of age as a predictor of vitamin D status, while accounting for body weight and skin colour, among a nationally representative sample. DESIGN: We calculated the mean serum 25-hydroxyvitamin D levels for the US population by age and weight, as well as by weight and race/ethnicity group. Multiple regression analyses were utilized to evaluate age and weight as predictors of vitamin D status: serum 25-hydroxyvitamin D levels with age alone, age and body weight, and age, body weight and their two-way interaction were modelled for the entire sample and each age subgroup. Graphical data were developed using B-spline non-linear regression. SETTING: National Health and Nutrition Examination Survey (31 934 unweighted cases). SUBJECTS: Individuals aged 1 year and older. RESULTS: There were highly significant differences in mean vitamin D status among US residents by weight and skin colour, with those having darker skin colour or higher body weight having worse vitamin D status. Although a significant factor, the impact of age on vitamin D status was notably less than the impact of body weight. CONCLUSIONS: Vitamin D status varied predominantly by body weight and skin colour. Recommendations by nutritionists for diet and supplementation needs should take this into account if vitamin D-related health disparities are to be meaningfully reduced across the USA.
OBJECTIVE: Current US dietary recommendations for vitamin D vary by age. Recent research suggests that body weight and skin colour are also major determinants of vitamin D status. The objective of the present epidemiological investigation was to clarify the role of age as a predictor of vitamin D status, while accounting for body weight and skin colour, among a nationally representative sample. DESIGN: We calculated the mean serum 25-hydroxyvitamin D levels for the US population by age and weight, as well as by weight and race/ethnicity group. Multiple regression analyses were utilized to evaluate age and weight as predictors of vitamin D status: serum 25-hydroxyvitamin D levels with age alone, age and body weight, and age, body weight and their two-way interaction were modelled for the entire sample and each age subgroup. Graphical data were developed using B-spline non-linear regression. SETTING: National Health and Nutrition Examination Survey (31 934 unweighted cases). SUBJECTS: Individuals aged 1 year and older. RESULTS: There were highly significant differences in mean vitamin D status among US residents by weight and skin colour, with those having darker skin colour or higher body weight having worse vitamin D status. Although a significant factor, the impact of age on vitamin D status was notably less than the impact of body weight. CONCLUSIONS:Vitamin D status varied predominantly by body weight and skin colour. Recommendations by nutritionists for diet and supplementation needs should take this into account if vitamin D-related health disparities are to be meaningfully reduced across the USA.
Entities:
Keywords:
Epidemiology; RDA; Supplements; Vitamin D
Authors: George Griffin; Martin Hewison; Julian Hopkin; Rose Kenny; Richard Quinton; Jonathan Rhodes; Sreedhar Subramanian; David Thickett Journal: R Soc Open Sci Date: 2020-12-01 Impact factor: 2.963
Authors: Mohammed Al Thani; Eman Sadoun; Angeliki Sofroniou; Amin Jayyousi; Khaled Ahmed Mohamed Baagar; Abdulla Al Hammaq; Benjamin Vinodson; Hammad Akram; Zaid Shakoor Bhatti; Heba Samir Nasser; Vasiliki Leventakou Journal: BMC Nutr Date: 2019-10-10