Literature DB >> 26866018

Recent update in HIV vaccine development.

So Youn Shin1.   

Abstract

Despite the tremendous efforts to develop a successful human immunodeficiency virus (HIV) vaccine, the quest for a safe and effective HIV vaccine seems to be remarkably long and winding. Disappointing results from previous clinical trials of VaxGen's AIDSVAXgp120 vaccine and MRKAd5 HIV-1 Gag/Pol/Nef vaccine emphasize that understanding the correlates of immune protection in HIV infection is the key to solve the puzzle. The modest vaccine efficacy from RV144 trial and the successive results obtained from the correlate of risk analysis have reinvigorated the HIV vaccine research field leading to various novel strategies. This paper will review the brief history and recent advances in HIV vaccine development.

Entities:  

Keywords:  Correlates; HIV; Prevention; Vaccines

Year:  2016        PMID： 26866018      PMCID： PMC4742600          DOI： 10.7774/cevr.2016.5.1.6

Source DB:  PubMed          Journal:  Clin Exp Vaccine Res        ISSN： 2287-3651


  42 in total

1.  Broadly neutralizing antibodies suppress HIV in the persistent viral reservoir.

Authors:  Tae-Wook Chun; Danielle Murray; Jesse S Justement; Jana Blazkova; Claire W Hallahan; Olivia Fankuchen; Kathleen Gittens; Erika Benko; Colin Kovacs; Susan Moir; Anthony S Fauci
Journal:  Proc Natl Acad Sci U S A       Date:  2014-08-25       Impact factor: 11.205

Review 2.  Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies.

Authors:  Peter D Kwong; John R Mascola
Journal:  Immunity       Date:  2012-09-21       Impact factor: 31.745

3.  Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand.

Authors:  Punnee Pitisuttithum; Peter Gilbert; Marc Gurwith; William Heyward; Michael Martin; Fritz van Griensven; Dale Hu; Jordan W Tappero; Kachit Choopanya
Journal:  J Infect Dis       Date:  2006-11-03       Impact factor: 5.226

4.  Mosaic vaccines elicit CD8+ T lymphocyte responses that confer enhanced immune coverage of diverse HIV strains in monkeys.

Authors:  Sampa Santra; Hua-Xin Liao; Ruijin Zhang; Mark Muldoon; Sydeaka Watson; Will Fischer; James Theiler; James Szinger; Harikrishnan Balachandran; Adam Buzby; David Quinn; Robert J Parks; Chun-Yen Tsao; Angela Carville; Keith G Mansfield; George N Pavlakis; Barbara K Felber; Barton F Haynes; Bette T Korber; Norman L Letvin
Journal:  Nat Med       Date:  2010-02-21       Impact factor: 53.440

5.  Immunology. Immune activation with HIV vaccines.

Authors:  Anthony S Fauci; Mary A Marovich; Carl W Dieffenbach; Eric Hunter; Susan P Buchbinder
Journal:  Science       Date:  2014-04-04       Impact factor: 47.728

6.  Genetic impact of vaccination on breakthrough HIV-1 sequences from the STEP trial.

Authors:  Morgane Rolland; Sodsai Tovanabutra; Allan C deCamp; Nicole Frahm; Peter B Gilbert; Eric Sanders-Buell; Laura Heath; Craig A Magaret; Meera Bose; Andrea Bradfield; Annemarie O'Sullivan; Jacqueline Crossler; Teresa Jones; Marty Nau; Kim Wong; Hong Zhao; Dana N Raugi; Stephanie Sorensen; Julia N Stoddard; Brandon S Maust; Wenjie Deng; John Hural; Sheri Dubey; Nelson L Michael; John Shiver; Lawrence Corey; Fusheng Li; Steve G Self; Jerome Kim; Susan Buchbinder; Danilo R Casimiro; Michael N Robertson; Ann Duerr; M Juliana McElrath; Francine E McCutchan; James I Mullins
Journal:  Nat Med       Date:  2011-02-27       Impact factor: 53.440

7.  Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection.

Authors:  Guido Ferrari; Bette Korber; Nilu Goonetilleke; Michael K P Liu; Emma L Turnbull; Jesus F Salazar-Gonzalez; Natalie Hawkins; Steve Self; Sydeaka Watson; Michael R Betts; Cynthia Gay; Kara McGhee; Pierre Pellegrino; Ian Williams; Georgia D Tomaras; Barton F Haynes; Clive M Gray; Persephone Borrow; Mario Roederer; Andrew J McMichael; Kent J Weinhold
Journal:  PLoS Pathog       Date:  2011-02-10       Impact factor: 6.823

8.  Magnitude and breadth of the neutralizing antibody response in the RV144 and Vax003 HIV-1 vaccine efficacy trials.

Authors:  David C Montefiori; Chitraporn Karnasuta; Ying Huang; Hasan Ahmed; Peter Gilbert; Mark S de Souza; Robert McLinden; Sodsai Tovanabutra; Agnes Laurence-Chenine; Eric Sanders-Buell; M Anthony Moody; Mattia Bonsignori; Christina Ochsenbauer; John Kappes; Haili Tang; Kelli Greene; Hongmei Gao; Celia C LaBranche; Charla Andrews; Victoria R Polonis; Supachai Rerks-Ngarm; Punnee Pitisuttithum; Sorachai Nitayaphan; Jaranit Kaewkungwal; Steve G Self; Phillip W Berman; Donald Francis; Faruk Sinangil; Carter Lee; Jim Tartaglia; Merlin L Robb; Barton F Haynes; Nelson L Michael; Jerome H Kim
Journal:  J Infect Dis       Date:  2012-05-25       Impact factor: 5.226

9.  Immune clearance of highly pathogenic SIV infection.

Authors:  Scott G Hansen; Michael Piatak; Abigail B Ventura; Colette M Hughes; Roxanne M Gilbride; Julia C Ford; Kelli Oswald; Rebecca Shoemaker; Yuan Li; Matthew S Lewis; Awbrey N Gilliam; Guangwu Xu; Nathan Whizin; Benjamin J Burwitz; Shannon L Planer; John M Turner; Alfred W Legasse; Michael K Axthelm; Jay A Nelson; Klaus Früh; Jonah B Sacha; Jacob D Estes; Brandon F Keele; Paul T Edlefsen; Jeffrey D Lifson; Louis J Picker
Journal:  Nature       Date:  2013-09-11       Impact factor: 49.962

10.  Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys.

Authors:  Dan H Barouch; James B Whitney; Brian Moldt; Florian Klein; Thiago Y Oliveira; Jinyan Liu; Kathryn E Stephenson; Hui-Wen Chang; Karthik Shekhar; Sanjana Gupta; Joseph P Nkolola; Michael S Seaman; Kaitlin M Smith; Erica N Borducchi; Crystal Cabral; Jeffrey Y Smith; Stephen Blackmore; Srisowmya Sanisetty; James R Perry; Matthew Beck; Mark G Lewis; William Rinaldi; Arup K Chakraborty; Pascal Poignard; Michel C Nussenzweig; Dennis R Burton
Journal:  Nature       Date:  2013-10-30       Impact factor: 49.962
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  6 in total

Review 1.  Vaccine nanoparticles for protection against HIV infection.

Authors:  Marisa E Aikins; Joseph Bazzill; James J Moon
Journal:  Nanomedicine (Lond)       Date:  2017-02-21       Impact factor: 5.307

Review 2.  Toward DNA-Based T-Cell Mediated Vaccines to Target HIV-1 and Hepatitis C Virus: Approaches to Elicit Localized Immunity for Protection.

Authors:  Zelalem A Mekonnen; Branka Grubor-Bauk; Makutiro G Masavuli; Ashish C Shrestha; Charani Ranasinghe; Rowena A Bull; Andrew R Lloyd; Eric J Gowans; Danushka K Wijesundara
Journal:  Front Cell Infect Microbiol       Date:  2019-04-03       Impact factor: 5.293

3.  Engineered Zinc Finger Protein Targeting 2LTR Inhibits HIV Integration in Hematopoietic Stem and Progenitor Cell-Derived Macrophages: In Vitro Study.

Authors:  Koollawat Chupradit; Wannisa Khamaikawin; Supachai Sakkhachornphop; Chaniporn Puaninta; Bruce E Torbett; Suparerk Borwornpinyo; Suradej Hongeng; Methichit Wattanapanitch; Chatchai Tayapiwatana
Journal:  Int J Mol Sci       Date:  2022-02-19       Impact factor: 5.923

4.  T = 4 Icosahedral HIV-1 Capsid As an Immunogenic Vector for HIV-1 V3 Loop Epitope Display.

Authors:  Zhiqing Zhang; Maozhou He; Shimeng Bai; Feng Zhang; Jie Jiang; Qingbing Zheng; Shuangquan Gao; Xiaodong Yan; Shaowei Li; Ying Gu; Ningshao Xia
Journal:  Viruses       Date:  2018-11-26       Impact factor: 5.048

Review 5.  Immunotherapeutic strategies for sexually transmitted viral infections: HIV, HSV and HPV.

Authors:  Braira Wahid; Amjad Ali; Muhammad Idrees; Shazia Rafique
Journal:  Cell Immunol       Date:  2016-08-03       Impact factor: 4.868

6.  Evaluation of antiviral T cell responses and TSCM cells in volunteers enrolled in a phase I HIV-1 subtype C prophylactic vaccine trial in India.

Authors:  Sivasankaran Munusamy Ponnan; Peter Hayes; Natalia Fernandez; Kannan Thiruvengadam; Sathyamurthi Pattabiram; Manohar Nesakumar; Ashokkumar Srinivasan; Sujitha Kathirvel; Janani Shankar; Rajat Goyal; Nikhil Singla; Joyeeta Mukherjee; Shweta Chatrath; Jill Gilmour; Sudha Subramanyam; Srikanth Prasad Tripathy; Soumya Swaminathan; Luke Elizabeth Hanna
Journal:  PLoS One       Date:  2020-02-25       Impact factor: 3.240
  6 in total

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