Literature DB >> 268629

Isolation and identification of aliphatic short-chain acylcarnitines from beef heart: possible role for carnitine in branched-chain amino acid metabolism.

L L Bieber, Y R Choi.   

Abstract

Aliphatic acylearnitines isolated from a water-soluble fraction of beef heart have been characterized by gas chromatography and mass spectrometry. The following acyl residues derived from the acylcarnitine fraction were unequivocally identified: acetyl, propionyl, isobutyryl, butyryl, alpha-methylbutyryl, valeryl, isovaleryl, tiglyl, and caproyl. beta-methylcrotonyl and methacrylyl were tentatively identified. This occurrence of considerable quantities of branched-chain acylcarnitines indicates a role for carnitine in branched-chain amino acid metabolism.

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Year:  1977        PMID： 268629      PMCID： PMC431294          DOI： 10.1073/pnas.74.7.2795

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  31 in total

1.  Localization and solubilization of a rat liver microsomal carnitine acetyltransferase.

Authors:  M A Markwell; L L Bieber
Journal:  Arch Biochem Biophys       Date:  1976-02       Impact factor: 4.013

2.  Comparison of the carnitine acyltransferase activites from rat liver peroxisomes and microsomes.

Authors:  M A Markwell; N E Tolbert; L L Bieber
Journal:  Arch Biochem Biophys       Date:  1976-10       Impact factor: 4.013

3.  A method for the isolation, identification, and quantitation of water-soluble aliphatic acylcarnitines.

Authors:  Y R Choi; L L Bieber
Journal:  Anal Biochem       Date:  1977-05-01       Impact factor: 3.365

4.  Glyoxylate aminotransferase in peroxisomes from rat liver and kidney.

Authors:  B Hsieh; N E Tolbert
Journal:  J Biol Chem       Date:  1976-07-25       Impact factor: 5.157

5.  Metabolic action of palmitoylcarnitine on rat liver mitochondria.

Authors:  R Portenhauser; G Schäfer; W Lamprecht
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1969-05

6.  Identification of peroxisomes (microbodies) in mouse myocardium.

Authors:  V Herzog; H D Fahimi
Journal:  J Mol Cell Cardiol       Date:  1976-04       Impact factor: 5.000

7.  Regulation of branched-chain amino acid oxidation in isolated muscles, nerves and aortas of rats.

Authors:  M G Buse; S Jursinic; S S Reid
Journal:  Biochem J       Date:  1975-06       Impact factor: 3.857

8.  Effect of clofibrate treatment on carnitine acyltransferases in different subcellular fractions of rat liver.

Authors:  M T Kahonen
Journal:  Biochim Biophys Acta       Date:  1976-05-28

9.  A fatty acyl-CoA oxidizing system in rat liver peroxisomes; enhancement by clofibrate, a hypolipidemic drug.

Authors:  P B Lazarow; C De Duve
Journal:  Proc Natl Acad Sci U S A       Date:  1976-06       Impact factor: 11.205

10.  Role of carnitine in hepatic ketogenesis.

Authors:  J D McGarry; C Robles-Valdes; D W Foster
Journal:  Proc Natl Acad Sci U S A       Date:  1975-11       Impact factor: 11.205
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Authors:  M Duran; F J van Sprang; J G Drewes; L Bruinvis; D Ketting; S K Wadman
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4.  Age-associated deficit of mitochondrial oxidative phosphorylation in skeletal muscle: role of carnitine and lipoic acid.

Authors:  S Kumaran; Kavin S Panneerselvam; S Shila; K Sivarajan; C Panneerselvam
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5.  Leucine oxidation and protein turnover in clofibrate-induced muscle protein degradation in rats.

Authors:  H S Paul; S A Adibi
Journal:  J Clin Invest       Date:  1980-06       Impact factor: 14.808

6.  Association between alterations in plasma metabolome profiles and laminitis in intensively finished Holstein bulls in a randomized controlled study.

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Journal:  Sci Rep       Date:  2021-06-17       Impact factor: 4.379

7.  An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs.

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  7 in total

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