| Literature DB >> 2686112 |
Abstract
It has long been suggested that pattern formation depends in part on signalling molecules known as 'morphogens', diffusible substances that determine cell fate in a concentration-dependent way. Retinoic acid, a small hydrophobic molecule that binds to nuclear receptors, is a candidate morphogen for specifying the anteroposterior pattern of vertebrate limbs.Entities:
Mesh:
Substances:
Year: 1989 PMID: 2686112 DOI: 10.1016/0168-9525(89)90096-6
Source DB: PubMed Journal: Trends Genet ISSN: 0168-9525 Impact factor: 11.639