| Literature DB >> 26857333 |
Jangsup Moon1, Han Sang Lee2, Jung-Ick Byun2, Jun-Sang Sunwoo2, Jung-Won Shin3, Jung-Ah Lim2, Tae-Joon Kim2, Yong-Won Shin2, Keon-Joo Lee2, Daejong Jeon2, Keun-Hwa Jung2, Soon-Tae Lee2, Ki-Young Jung2, Kon Chu4, Sang Kun Lee5.
Abstract
We investigated how the diagnosis of postural orthostatic tachycardia syndrome (POTS) would be changed due to diurnal variability in orthostatic tachycardia. The orthostatic vital sign test was administered to each patient twice, in the afternoon of the day of admission and the next morning (n = 113). Forty-six patients were diagnosed with POTS, and the remaining 67 patients were assigned to non-POTS group. Heart rate increments after standing were larger in the morning than in the afternoon in every group (all P < .001). Among the POTS patients, 82.6% fulfilled the diagnostic criteria for POTS in the morning and 52.2% in the afternoon. Most POTS group (65.2%) displayed normal result on single orthostatic vital sign test. Orthostatic intolerance symptoms were provoked in only 45.7% of the POTS patients, more frequently in the morning. In conclusion, diurnal variability in hemodynamic parameters and provoked symptoms significantly challenged the diagnosis of POTS.Entities:
Keywords: Postural tachycardia syndrome; diurnal variability; orthostatic hypotension; orthostatic intolerance; orthostatic tachycardia
Mesh：
Year: 2016 PMID： 26857333 DOI： 10.1016/j.jash.2016.01.011
Source DB: PubMed Journal: J Am Soc Hypertens ISSN： 1878-7436