Mieke Maris1, Stijn Verhulst2, Marek Wojciechowski3, Paul Van de Heyning4, An Boudewyns5. 1. Department of Otorhinolaryngology, Head and Neck Surgery, University of Antwerp, Antwerp University Hospital, Wilrijkstraat 10, Edegem 2650, Belgium. Electronic address: mieke.maris@gmail.com. 2. Department of Paediatrics, University of Antwerp, Antwerp University Hospital, Wilrijkstraat 10, Edegem 2650, Belgium. Electronic address: stijn.verhulst@uza.be. 3. Department of Paediatrics, University of Antwerp, Antwerp University Hospital, Wilrijkstraat 10, Edegem 2650, Belgium. Electronic address: marek.wojciechowski@uza.be. 4. Department of Otorhinolaryngology, Head and Neck Surgery, University of Antwerp, Antwerp University Hospital, Wilrijkstraat 10, Edegem 2650, Belgium. Electronic address: paul.van.de.heying@uza.be. 5. Department of Otorhinolaryngology, Head and Neck Surgery, University of Antwerp, Antwerp University Hospital, Wilrijkstraat 10, Edegem 2650, Belgium. Electronic address: an.boudewyns@uza.be.
Abstract
INTRODUCTION: Children with Down syndrome (DS) have a high prevalence of sleep problems, including behavioural sleep disturbances and obstructive sleep apnea. Sleep problems are associated with a wide range of adverse health effects. Since children with DS are already known to have many comorbidities, they are particularly susceptible for the negative impact of sleep problems. Aim of this study is (1) to evaluate the prevalence of sleep problems in children with DS, (2) compare the prevalence of sleep problems in children with DS with a community sample of typical developing school-aged children, and (3) to correlate the existence of sleep problems in children with DS and OSA. METHODS: Children enrolled at the multidisciplinary Down team of the University Hospital Antwerp and seen at the ENT department were eligible for this study. The prevalence of sleep problems was evaluated by the use of the Child Sleep Habits Questionnaire (CSHQ) and a full overnight polysomnography was performed to screen for obstructive sleep apnea. RESULTS: Parents of fifty-four children with DS, aged 7.5 years (5.4-11.6), completed the CSHQ and an overall prevalence of sleep problems was found in 74.1%. In 57.1% of the children OSA was diagnosed with a median obstructive apnea-hypopnea index (oAHI) 7.25/h (5.7-9.8). Overall sleep problems were not age-or gender related, however boys suffer more from daytime sleepiness. Symptoms of sleep disordered breathing correlate with parasomnias, a longer sleep duration and more daytime sleepiness. No correlation was found between sleep problems and underlying OSA. CONCLUSION: Children with Down syndrome have a significantly higher prevalence of sleep problems, compared to normal developing healthy school-aged children. We didn't find any correlation between the parental report of sleep problems and underlying OSA, or OSA severity.
INTRODUCTION:Children with Down syndrome (DS) have a high prevalence of sleep problems, including behavioural sleep disturbances and obstructive sleep apnea. Sleep problems are associated with a wide range of adverse health effects. Since children with DS are already known to have many comorbidities, they are particularly susceptible for the negative impact of sleep problems. Aim of this study is (1) to evaluate the prevalence of sleep problems in children with DS, (2) compare the prevalence of sleep problems in children with DS with a community sample of typical developing school-aged children, and (3) to correlate the existence of sleep problems in children with DS and OSA. METHODS:Children enrolled at the multidisciplinary Down team of the University Hospital Antwerp and seen at the ENT department were eligible for this study. The prevalence of sleep problems was evaluated by the use of the Child Sleep Habits Questionnaire (CSHQ) and a full overnight polysomnography was performed to screen for obstructive sleep apnea. RESULTS: Parents of fifty-four children with DS, aged 7.5 years (5.4-11.6), completed the CSHQ and an overall prevalence of sleep problems was found in 74.1%. In 57.1% of the children OSA was diagnosed with a median obstructive apnea-hypopnea index (oAHI) 7.25/h (5.7-9.8). Overall sleep problems were not age-or gender related, however boys suffer more from daytime sleepiness. Symptoms of sleep disordered breathing correlate with parasomnias, a longer sleep duration and more daytime sleepiness. No correlation was found between sleep problems and underlying OSA. CONCLUSION:Children with Down syndrome have a significantly higher prevalence of sleep problems, compared to normal developing healthy school-aged children. We didn't find any correlation between the parental report of sleep problems and underlying OSA, or OSA severity.
Authors: Sarah R Akkina; Cheng C Ma; Erin M Kirkham; David L Horn; Maida L Chen; Sanjay R Parikh Journal: Acta Otolaryngol Date: 2018-11 Impact factor: 1.494
Authors: Anna J Esbensen; Stephen R Hooper; Deborah Fidler; Sigan L Hartley; Jamie Edgin; Xavier Liogier d'Ardhuy; George Capone; Frances A Conners; Carolyn B Mervis; Leonard Abbeduto; Michael Rafii; Sharon J Krinsky-McHale; Tiina Urv Journal: Am J Intellect Dev Disabil Date: 2017-05
Authors: Monique A L J Slaats; Dieter Loterman; Cedric van Holsbeke; Wim Vos; Kim Van Hoorenbeeck; Jan de Backer; Wilfried de Backer; Marek Wojciechowski; An Boudewyns; Stijn Verhulst Journal: J Clin Sleep Med Date: 2018-04-15 Impact factor: 4.062
Authors: Fabian Fernandez; Casandra C Nyhuis; Payal Anand; Bianca I Demara; Norman F Ruby; Goffredina Spanò; Caron Clark; Jamie O Edgin Journal: Sleep Med Date: 2017-02-10 Impact factor: 3.492