OBJECTIVE: The purpose of this study was to analyze and demonstrate the heterogeneity in adult spinal deformity (ASD) populations by baseline health-related quality of life (HRQL) data. METHODS: ASD was defined as patients over 18 years of age with any of the following: coronal deformity >20°, sagittal vertical axis (SVA) >5 cm, pelvic tilt >25°, or thoracic kyphosis >60°. Three hundred fifty-two patients meeting the above definition of ASD were analyzed for measures of HRQL (Oswestry disability index [ODI], SRS-22 [Scoliosis Research Society-22], and SF-36 [Short form-36 health survey] questionnaires) at presentation. Age groups were defined as 18-40, 40-60, and >60 years. Deformity was analyzed as either degenerative (DS) or idiopathic (IS) (294 patients; 71 degenerative, 223 idiopathic). RESULTS: There were significant differences between age groups--predominantly between the lower age group (18-40) and others--for all HRQL parameters except SRS-22 mental health and SF-36 mental component score. Similarly, HRQL measures for DS and IS deformities were significantly different. Regarding location of main curves, thoracolumbar/lumbar (TL/L) (70.2%) was dominant for the DS group and thoracic (55%) for the IS group. Mean age was 65 years for the DS group and 36 for the IS group, which were significantly different. Radiographic parameters were also significantly different between these groups, with IS patients having more coronal deformity and better sagittal balance. CONCLUSION: ASD patients are very heterogeneous at presentation, depending on age and diagnosis. There is a distinct need to stratify ASD as early and late presentation ASD and/or by diagnosis. Patients with IS deformity may be very different from those with DS deformity, even at time of presentation. These differences must be taken into consideration in treatment of these patients, as well as for the analysis of the results of treatment.
OBJECTIVE: The purpose of this study was to analyze and demonstrate the heterogeneity in adult spinal deformity (ASD) populations by baseline health-related quality of life (HRQL) data. METHODS:ASD was defined as patients over 18 years of age with any of the following: coronal deformity >20°, sagittal vertical axis (SVA) >5 cm, pelvic tilt >25°, or thoracic kyphosis >60°. Three hundred fifty-two patients meeting the above definition of ASD were analyzed for measures of HRQL (Oswestry disability index [ODI], SRS-22 [Scoliosis Research Society-22], and SF-36 [Short form-36 health survey] questionnaires) at presentation. Age groups were defined as 18-40, 40-60, and >60 years. Deformity was analyzed as either degenerative (DS) or idiopathic (IS) (294 patients; 71 degenerative, 223 idiopathic). RESULTS: There were significant differences between age groups--predominantly between the lower age group (18-40) and others--for all HRQL parameters except SRS-22 mental health and SF-36 mental component score. Similarly, HRQL measures for DS and ISdeformities were significantly different. Regarding location of main curves, thoracolumbar/lumbar (TL/L) (70.2%) was dominant for the DS group and thoracic (55%) for the IS group. Mean age was 65 years for the DS group and 36 for the IS group, which were significantly different. Radiographic parameters were also significantly different between these groups, with ISpatients having more coronal deformity and better sagittal balance. CONCLUSION:ASDpatients are very heterogeneous at presentation, depending on age and diagnosis. There is a distinct need to stratify ASD as early and late presentation ASD and/or by diagnosis. Patients with ISdeformity may be very different from those with DSdeformity, even at time of presentation. These differences must be taken into consideration in treatment of these patients, as well as for the analysis of the results of treatment.
Authors: Takashi Fujishiro; Louis Boissière; Derek Thomas Cawley; Daniel Larrieu; Olivier Gille; Jean-Marc Vital; Ferran Pellisé; Francisco Javier Sanchez Pérez-Grueso; Frank Kleinstück; Emre Acaroglu; Ahmet Alanay; Ibrahim Obeid Journal: Eur Spine J Date: 2019-03-07 Impact factor: 3.134
Authors: Takashi Fujishiro; Louis Boissière; Derek Thomas Cawley; Daniel Larrieu; Olivier Gille; Jean-Marc Vital; Ferran Pellisé; Francisco Javier Sanchez Pérez-Grueso; Frank Kleinstück; Emre Acaroglu; Ahmet Alanay; Ibrahim Obeid Journal: Eur Spine J Date: 2019-07-17 Impact factor: 3.134
Authors: D T Cawley; M Takemoto; L Boissiere; D Larrieu; D C Kieser; T Fujishiro; K Hayashi; A Bourghli; C Yilgor; A Alanay; F J Perez Grueso; F Pelisse; F Kleinstück; J M Vital; I Obeid Journal: Eur Spine J Date: 2021-04-26 Impact factor: 3.134
Authors: Kazunori Hayashi; Louis Boissière; Fernando Guevara-Villazón; Daniel Larrieu; Anouar Bourghli; Olivier Gille; Jean-Marc Vital; Ferran Pellisé; Francisco Javier Sánchez Pérez-Grueso; Frank Kleinstück; Emre Acaroğlu; Ahmet Alanay; Hiroaki Nakamura; Ibrahim Obeid Journal: Eur Spine J Date: 2019-10-31 Impact factor: 3.134
Authors: Cem Karabulut; Selim Ayhan; Selcen Yuksel; Vugar Nabiyev; Alba Vila-Casademunt; Ferran Pellise; Ahmet Alanay; Francisco Javier Sanchez Perez-Grueso; Frank Kleinstuck; Ibrahim Obeid; Emre Acaroglu Journal: Int J Spine Surg Date: 2019-08-31
Authors: Ashish Patel; Jason Oh; Dante Leven; Frank S Cautela; Dipal Chatterjee; Qais Naziri; Francesco Langella; Bassel G Diebo; Carl B Paulino Journal: Int J Spine Surg Date: 2018-03-30