| Literature DB >> 26853477 |
Laurence Soussan1, Nakry Pen2, Marie-Pierre Belleville2, José Sanchez Marcano2, Delphine Paolucci-Jeanjean2.
Abstract
Alkanes constitute one of the vastest reserves of raw materials for the production of fine chemicals. This paper focuses on recent advances in alkane biohydroxylation, i.e. the bioactivation of alkanes into their corresponding alcohols. Enzyme and whole-cell biocatalysts have been reviewed. Process considerations to implement such biocatalysts in bioreactors at large scale by coupling the bioconversion with cofactor regeneration and product removal are also discussed.Entities:
Keywords: Alcohol removal; Alkanes; Biocatalysts; Biohydroxylation; Bioreactors; Cofactor regeneration
Mesh:
Substances:
Year: 2016 PMID: 26853477 DOI: 10.1016/j.jbiotec.2016.02.007
Source DB: PubMed Journal: J Biotechnol ISSN: 0168-1656 Impact factor: 3.307