Marie Fargier-Voiron1, Benoît Presles1, Pascal Pommier2, Alexandre Munoz2, Simon Rit1, David Sarrut3, Marie-Claude Biston4. 1. CREATIS, INSA, Université de Lyon, CNRS UMR5220, Inserm U1044, Lyon F-69622, France. 2. Léon Bérard Cancer Center, University of Lyon, Lyon F-69373, France. 3. CREATIS, INSA, Université de Lyon, CNRS UMR5220, Inserm U1044, Lyon F-69622, France; Léon Bérard Cancer Center, University of Lyon, Lyon F-69373, France. 4. CREATIS, INSA, Université de Lyon, CNRS UMR5220, Inserm U1044, Lyon F-69622, France; Léon Bérard Cancer Center, University of Lyon, Lyon F-69373, France. Electronic address: marie-claude.biston@lyon.unicancer.fr.
Abstract
PURPOSE: The aim of this study was to evaluate a new system based on transperineal ultrasound (TP-US) acquisitions for prostate and post-prostatectomy pre-treatment positioning by comparing this device to cone-beam computed tomography (CBCT). METHODS: The differences between CBCT/CT and TP-US/TP-US registrations were analyzed on 427 and 453 sessions for 13 prostate and 14 post-prostatectomy patients, respectively. The inter-operator variability (IOV) of the registration process, and the impact and variability of the probe pressure were also evaluated. RESULTS: CBCT and TP-US shift agreements at ± 5 mm were 76.6%, 95.1%, 96.3% and 90.3%, 85.0%, 97.6% in anterior-posterior, superior-inferior and left-right directions, for prostate and post-prostatectomy patients, respectively. IOV values were similar between the 2 modalities. Displacements above 5 mm due to strong pressures were observed on both localizations, but such pressures were rarely reproduced during treatment courses. CONCLUSIONS: High concordance between CBCT/CT and TP-US/TP-US localization of prostates or prostatic beds was found in this study. TP-US based prepositioning is a feasible method to ensure accurate treatment delivery, and represents an attractive alternative to invasive and/or irradiating imaging modalities.
PURPOSE: The aim of this study was to evaluate a new system based on transperineal ultrasound (TP-US) acquisitions for prostate and post-prostatectomy pre-treatment positioning by comparing this device to cone-beam computed tomography (CBCT). METHODS: The differences between CBCT/CT and TP-US/TP-US registrations were analyzed on 427 and 453 sessions for 13 prostate and 14 post-prostatectomy patients, respectively. The inter-operator variability (IOV) of the registration process, and the impact and variability of the probe pressure were also evaluated. RESULTS: CBCT and TP-US shift agreements at ± 5 mm were 76.6%, 95.1%, 96.3% and 90.3%, 85.0%, 97.6% in anterior-posterior, superior-inferior and left-right directions, for prostate and post-prostatectomy patients, respectively. IOV values were similar between the 2 modalities. Displacements above 5 mm due to strong pressures were observed on both localizations, but such pressures were rarely reproduced during treatment courses. CONCLUSIONS: High concordance between CBCT/CT and TP-US/TP-US localization of prostates or prostatic beds was found in this study. TP-US based prepositioning is a feasible method to ensure accurate treatment delivery, and represents an attractive alternative to invasive and/or irradiating imaging modalities.
Authors: Florent Vilotte; Mickael Antoine; Maxime Bobin; Igor Latorzeff; Stéphane Supiot; Pierre Richaud; Laurence Thomas; Nicolas Leduc; Stephane Guérif; Jone Iriondo-Alberdi; Renaud de Crevoisier; Paul Sargos Journal: Front Oncol Date: 2017-03-09 Impact factor: 6.244
Authors: Bin Han; Mohammad Najafi; David T Cooper; Martin Lachaine; Rie von Eyben; Steven Hancock; Dimitre Hristov Journal: Radiat Oncol Date: 2018-08-20 Impact factor: 3.481
Authors: Alexander Grimwood; Hassan Rivaz; Hang Zhou; Helen A McNair; Klaudiusz Jakubowski; Jeffrey C Bamber; Alison C Tree; Emma J Harris Journal: Radiother Oncol Date: 2020-05-06 Impact factor: 6.280
Authors: Saskia M Camps; Davide Fontanarosa; Peter H N de With; Frank Verhaegen; Ben G L Vanneste Journal: Biomed Res Int Date: 2018-01-24 Impact factor: 3.411
Authors: Mona Splinter; Tilman Bostel; Ilias Sachpazidis; Tobias Fechter; Constantinos Zamboglou; Oliver Jäkel; Peter E Huber; Jürgen Debus; Dimos Baltas; Nils H Nicolay Journal: Front Oncol Date: 2019-11-08 Impact factor: 6.244