Jinglu Ying1, Qinmei Wang2, Michael W Belin3, Ting Wan2, Shishi Lin2, Yifan Feng2, Rongrong Gao2, Jinhai Huang4. 1. School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China; Department of Ophthalmology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China. 2. School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China. 3. Department of Ophthalmology, University of Arizona, Tucson, AV, United States. 4. School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China. Electronic address: vip999vip@163.com.
Abstract
PURPOSE: To establish a normative database for corneal elevation in Chinese myopic patients who underwent refractive surgery, and analyze the association of corneal elevation with sex, age, and ocular parameters. METHODS: A total of 3000 eyes in 1500 patients were evaluated with the Pentacam. Anterior and posterior elevations were measured at the apex and thinnest point. Normative thresholds were defined according to the Tukey method. Univariate and multivariate analyses were performed to assess the association of corneal elevation with sex, age, and ocular parameters. RESULTS: Normal upper limits for corneal elevation in adult Chinese were 4.95μm, 5.25μm, 6.2μm, and 11.0μm at the anterior apex, anterior thinnest point, posterior apex, and posterior thinnest point, respectively. Thinner corneal pachymetry at the apex and greater anterior corneal astigmatism tended to show greater anterior corneal elevation values. Younger age, greater anterior corneal astigmatism, lower anterior and posterior keratometry, and shallower anterior chamber depth resulted in greater posterior corneal elevation values. CONCLUSIONS: Locally derived thresholds may offer higher sensitivity and specificity when screening eyes for myopic refractive surgery, and keratoconic and post-orthokeratology eyes. Anterior and posterior corneal elevation at the apex and thinnest point were associated significantly with anterior corneal astigmatism, showing a positive correlation.
PURPOSE: To establish a normative database for corneal elevation in Chinese myopic patients who underwent refractive surgery, and analyze the association of corneal elevation with sex, age, and ocular parameters. METHODS: A total of 3000 eyes in 1500 patients were evaluated with the Pentacam. Anterior and posterior elevations were measured at the apex and thinnest point. Normative thresholds were defined according to the Tukey method. Univariate and multivariate analyses were performed to assess the association of corneal elevation with sex, age, and ocular parameters. RESULTS: Normal upper limits for corneal elevation in adult Chinese were 4.95μm, 5.25μm, 6.2μm, and 11.0μm at the anterior apex, anterior thinnest point, posterior apex, and posterior thinnest point, respectively. Thinner corneal pachymetry at the apex and greater anterior corneal astigmatism tended to show greater anterior corneal elevation values. Younger age, greater anterior corneal astigmatism, lower anterior and posterior keratometry, and shallower anterior chamber depth resulted in greater posterior corneal elevation values. CONCLUSIONS: Locally derived thresholds may offer higher sensitivity and specificity when screening eyes for myopic refractive surgery, and keratoconic and post-orthokeratology eyes. Anterior and posterior corneal elevation at the apex and thinnest point were associated significantly with anterior corneal astigmatism, showing a positive correlation.