Ling Zhu1, Chunye Zhang2, Yi Hua3, Jie Yang4, Qiang Yu1, Xiaofeng Tao1, Jiawei Zheng5. 1. 1 Department of Radiology, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. 2. 2 Department of Oral pathology, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. 3. 3 Department of prevention and health care, Preventive and health care center of Wuzhong economic developing-area, Suzhou, China. 4. 4 Division of Oral & Maxillofacial Radiology, Temple University School of Dentistry, and Department of Diagnostic Imaging, Temple University School of Medicine, PA, USA. 5. 5 Department of Oral and Maxillofacial Surgery, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Abstract
OBJECTIVE: The aim of this study was to determine if dynamic contrast-enhanced (DCE)-MRI can differentiate mucosa-associated lymphoid tissue (MALT) lymphoma from benign lymphoepithelial lesion (BLEL) in the parotid gland. METHODS: 25 patients with tumour-like BLEL and 20 patients with MALT lymphoma in the parotid gland confirmed by pathology were examined pre-operatively using routine MR series and DCE-MRI with a 1.5-T MR unit. The time to peak (TTP), time to start (TTS), SIstart, SImax and SIending were measured and the initial slope of increase (ISI) and relative washout ratio (RWO) were calculated separately from the time-intensity curve (TIC), and the types of TIC were analysed. RESULTS: There were significant differences in the TTP and ISI between the two lesions (p < 0.001). The sensitivity, specificity and accuracy of TTP were all more than 90%. TICs were divided into three types according to the threshold of TTP and ISI: tumour-like BLEL: gradual type (Type II) and late increase type (Type III); MALT lymphoma: rapid increase and gradual type (Type I). CONCLUSIONS: DCE-MRI contributed greatly to the differential diagnosis between tumour-like BLEL and MALT lymphoma in the parotid gland.
OBJECTIVE: The aim of this study was to determine if dynamic contrast-enhanced (DCE)-MRI can differentiate mucosa-associated lymphoid tissue (MALT) lymphoma from benign lymphoepithelial lesion (BLEL) in the parotid gland. METHODS: 25 patients with tumour-like BLEL and 20 patients with MALT lymphoma in the parotid gland confirmed by pathology were examined pre-operatively using routine MR series and DCE-MRI with a 1.5-T MR unit. The time to peak (TTP), time to start (TTS), SIstart, SImax and SIending were measured and the initial slope of increase (ISI) and relative washout ratio (RWO) were calculated separately from the time-intensity curve (TIC), and the types of TIC were analysed. RESULTS: There were significant differences in the TTP and ISI between the two lesions (p < 0.001). The sensitivity, specificity and accuracy of TTP were all more than 90%. TICs were divided into three types according to the threshold of TTP and ISI: tumour-like BLEL: gradual type (Type II) and late increase type (Type III); MALT lymphoma: rapid increase and gradual type (Type I). CONCLUSIONS: DCE-MRI contributed greatly to the differential diagnosis between tumour-like BLEL and MALT lymphoma in the parotid gland.
Authors: Nancy J Fischbein; Susan M Noworolski; Roland G Henry; Michael J Kaplan; William P Dillon; Sarah J Nelson Journal: AJNR Am J Neuroradiol Date: 2003-03 Impact factor: 3.825
Authors: Susan M Noworolski; Nancy J Fischbein; Michael J Kaplan; Ying Lu; Sarah J Nelson; Lucas Carvajal; Roland G Henry Journal: J Magn Reson Imaging Date: 2003-04 Impact factor: 4.813