Literature DB >> 26845397

Big Data: Challenges and opportunities for clinical pharmacology.

David Flockhart1, Robert R Bies2, Marc R Gastonguay3, Sorell L Schwartz4.   

Abstract

Mesh:

Year:  2016        PMID: 26845397      PMCID: PMC4834592          DOI: 10.1111/bcp.12896

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN: 0306-5251            Impact factor:   4.335


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  8 in total

1.  Big Data: Challenges and opportunities for clinical pharmacology.

Authors:  David Flockhart; Robert R Bies; Marc R Gastonguay; Sorell L Schwartz
Journal:  Br J Clin Pharmacol       Date:  2016-03-04       Impact factor: 4.335

2.  Could Big Data be the end of theory in science? A few remarks on the epistemology of data-driven science.

Authors:  Fulvio Mazzocchi
Journal:  EMBO Rep       Date:  2015-09-10       Impact factor: 8.807

3.  Big data. The parable of Google Flu: traps in big data analysis.

Authors:  David Lazer; Ryan Kennedy; Gary King; Alessandro Vespignani
Journal:  Science       Date:  2014-03-14       Impact factor: 47.728

4.  Identified metabolic signature for assessing red blood cell unit quality is associated with endothelial damage markers and clinical outcomes.

Authors:  Aarash Bordbar; Pär I Johansson; Giuseppe Paglia; Scott J Harrison; Kristine Wichuk; Manuela Magnusdottir; Sóley Valgeirsdottir; Mikkel Gybel-Brask; Sisse R Ostrowski; Sirus Palsson; Ottar Rolfsson; Olafur E Sigurjónsson; Morten B Hansen; Sveinn Gudmundsson; Bernhard O Palsson
Journal:  Transfusion       Date:  2016-01-08       Impact factor: 3.157

5.  An integrated pharmacokinetics ontology and corpus for text mining.

Authors:  Heng-Yi Wu; Shreyas Karnik; Abhinita Subhadarshini; Zhiping Wang; Santosh Philips; Xu Han; Chienwei Chiang; Lei Liu; Malaz Boustani; Luis M Rocha; Sara K Quinney; David Flockhart; Lang Li
Journal:  BMC Bioinformatics       Date:  2013-02-01       Impact factor: 3.169

6.  Identification and Mechanistic Investigation of Drug-Drug Interactions Associated With Myopathy: A Translational Approach.

Authors:  X Han; S K Quinney; Z Wang; P Zhang; J Duke; Z Desta; J S Elmendorf; D A Flockhart; L Li
Journal:  Clin Pharmacol Ther       Date:  2015-09       Impact factor: 6.875

7.  What Difference Does Quantity Make? On the Epistemology of Big Data in Biology.

Authors:  Sabina Leonelli
Journal:  Big Data Soc       Date:  2014-06-01

8.  Systems biology-guided identification of synthetic lethal gene pairs and its potential use to discover antibiotic combinations.

Authors:  Ramy K Aziz; Jonathan M Monk; Robert M Lewis; Suh In Loh; Arti Mishra; Amrita Abhay Nagle; Chitkala Satyanarayana; Saravanakumar Dhakshinamoorthy; Michele Luche; Douglas B Kitchen; Kathleen A Andrews; Nicole L Fong; Howard J Li; Bernhard O Palsson; Pep Charusanti
Journal:  Sci Rep       Date:  2015-11-04       Impact factor: 4.379

  8 in total
  4 in total

1.  Big Data: Challenges and opportunities for clinical pharmacology.

Authors:  David Flockhart; Robert R Bies; Marc R Gastonguay; Sorell L Schwartz
Journal:  Br J Clin Pharmacol       Date:  2016-03-04       Impact factor: 4.335

Review 2.  Opportunities and Challenges for Drug Development: Public-Private Partnerships, Adaptive Designs and Big Data.

Authors:  Oktay Yildirim; Matthias Gottwald; Peter Schüler; Martin C Michel
Journal:  Front Pharmacol       Date:  2016-12-06       Impact factor: 5.810

3.  Macrolide Treatment Failure due to Drug-Drug Interactions: Real-World Evidence to Evaluate a Pharmacological Hypothesis.

Authors:  Brian Cicali; Stephan Schmidt; Markus Zeitlinger; Joshua D Brown
Journal:  Pharmaceutics       Date:  2022-03-25       Impact factor: 6.525

4.  Computational pharmacology: New avenues for COVID-19 therapeutics search and better preparedness for future pandemic crises.

Authors:  Austė Kanapeckaitė; Asta Mažeikienė; Liesbet Geris; Neringa Burokienė; Graeme S Cottrell; Darius Widera
Journal:  Biophys Chem       Date:  2022-09-11       Impact factor: 3.628

  4 in total

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