| Literature DB >> 26839518 |
Malgorzata E Skaznik-Wikiel1, Sara Babcock Gilbert1, Randall B Meacham2, Laxmi A Kondapalli.
Abstract
Approximately 0.2% of Americans aged 20 to 39 years are childhood cancer survivors. Advances in cancer detection and therapy have greatly improved survival rates for young cancer patients; however, treatment of childhood cancers can adversely impact reproductive function. Many cancer patients report a strong desire to be informed of existing options for fertility preservation and future reproduction prior to initiation of gonadotoxic cancer therapies, including surgery, chemotherapy, and radiotherapy. This article discusses, in detail, the effects of cancer treatment on fertility in men and women, and outlines both current and experimental methods of fertility preservation among cancer patients.Entities:
Keywords: Childhood cancer; Embryo cryopreservation; Fertility preservation; Oocyte cryopreservation; Ovarian tissue cryopreservation; Sperm cryopreservation; Spermatogonial stem cell cryopreservation; Testicular tissue cryopreservation
Year: 2015 PMID: 26839518 PMCID: PMC4735667
Source DB: PubMed Journal: Rev Urol ISSN: 1523-6161