Literature DB >> 20400139

Treatment for ejaculatory dysfunction in men with spinal cord injury: an 18-year single center experience.

Nancy L Brackett1, Emad Ibrahim, Viacheslav Iremashvili, Teodoro C Aballa, Charles M Lynne.   

Abstract

PURPOSE: In what is to our knowledge the largest study of its kind to date we retrospectively reviewed the records of 3,152 semen retrieval procedures in a total of 500 men with spinal cord injury to make recommendations to the medical field on ejaculatory dysfunction treatment in this specialized patient population.
MATERIALS AND METHODS: We retrospectively studied data from 1991 to 2009 in the Miami Project to Cure Paralysis male fertility research program at our institution. We assessed the semen retrieval success rate and semen quality.
RESULTS: Of the 500 men 9% could ejaculate by masturbation. Penile vibratory stimulation was successful in 86% of patients with a T10 or rostral injury level. Electroejaculation was successful in most cases of failed penile vibratory stimulation. Sperm were obtained without surgical sperm retrieval, in 97% of patients completing the treatment algorithm. Total motile sperm counts exceeded 5 million in 63% of cases.
CONCLUSIONS: Sperm can be easily obtained nonsurgically from most men with spinal cord injury. Sufficient sperm are available for simple insemination procedures. A treatment algorithm based on our experience is presented. Copyright 2010 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20400139     DOI: 10.1016/j.juro.2010.02.018

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  31 in total

1.  Ejaculation and sperm characteristics in men with cauda equina and conus medullaris syndromes.

Authors:  N Hadiji; R Mieusset; J G Previnaire; E Castel-Lacanal; J M Soler
Journal:  Spinal Cord       Date:  2017-02-14       Impact factor: 2.772

Review 2.  A step-wise approach to sperm retrieval in men with neurogenic anejaculation.

Authors:  Mikkel Fode; Dana A Ohl; Jens Sønksen
Journal:  Nat Rev Urol       Date:  2015-10-20       Impact factor: 14.432

3.  Chronic Spinal Cord Injury Reduces Gastrin-Releasing Peptide in the Spinal Ejaculation Generator in Male Rats.

Authors:  J Walker Wiggins; Natalie Kozyrev; Jonathan E Sledd; George G Wilson; Lique M Coolen
Journal:  J Neurotrauma       Date:  2019-07-10       Impact factor: 5.269

4.  Two cases of psychogenic anejaculation patients got normal ejaculation ability after penile vibratory stimulation or electroejaculation.

Authors:  Rong Cong; Qijie Zhang; Yi Wang; Xianghu Meng; Zengjun Wang; Ninghong Song
Journal:  Transl Androl Urol       Date:  2019-12

Review 5.  Male sexual dysfunction and infertility associated with neurological disorders.

Authors:  Mikkel Fode; Sheila Krogh-Jespersen; Nancy L Brackett; Dana A Ohl; Charles M Lynne; Jens Sønksen
Journal:  Asian J Androl       Date:  2011-12-05       Impact factor: 3.285

6.  Prevalence of parenthood in wheelchair-dependent persons with long-term spinal cord injury in the Netherlands.

Authors:  K van den Borne; I Brands; D Spijkerman; J J E Adriaansen; K Postma; H J G van den Berg-Emons
Journal:  Spinal Cord       Date:  2018-01-19       Impact factor: 2.772

7.  Comparison of three methods of penile vibratory stimulation for semen retrieval in men with spinal cord injury.

Authors:  W Chong; E Ibrahim; T C Aballa; C M Lynne; N L Brackett
Journal:  Spinal Cord       Date:  2017-05-30       Impact factor: 2.772

8.  Changes in Gene Expression and Metabolism in the Testes of the Rat following Spinal Cord Injury.

Authors:  Ryan D Fortune; Raymond J Grill; Christine Beeton; Mark Tanner; Redwan Huq; David S Loose
Journal:  J Neurotrauma       Date:  2016-12-02       Impact factor: 5.269

9.  Midodrine in patients with spinal cord injury and anejaculation: A double-blind randomized placebo-controlled pilot study.

Authors:  Bernard E Leduc; Christine Fournier; Géraldine Jacquemin; Yves Lepage; Bernard Vinet; Pierre-Olivier Hétu; Miguel Chagnon
Journal:  J Spinal Cord Med       Date:  2014-06-26       Impact factor: 1.985

Review 10.  Reproductive Health of Men with Spinal Cord Injury.

Authors:  Varsha Sinha; Stacy Elliott; Emad Ibrahim; Charles M Lynne; Nancy L Brackett
Journal:  Top Spinal Cord Inj Rehabil       Date:  2017
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