Literature DB >> 26820437

Ramping up degradation for proliferation.

Jon M Huibregtse1, Andreas Matouschek1.   

Abstract

The control of proteasome-mediated protein degradation is thought to occur mainly at the level of polyubiquitylation of the substrate. However, the proteasome can also be regulated directly, as now demonstrated by a study in which DYRK2-mediated phosphorylation of the 19S subunit Rpt3 is found to increase proteasome activity.

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Year:  2016        PMID： 26820437     DOI： 10.1038/ncb3306

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  14 in total

1.  Impairment of the ubiquitin-proteasome system by protein aggregation.

Authors:  N F Bence; R M Sampat; R R Kopito
Journal:  Science       Date:  2001-05-25       Impact factor: 47.728

Review 2.  Building on bortezomib: second-generation proteasome inhibitors as anti-cancer therapy.

Authors:  Lawrence R Dick; Paul E Fleming
Journal:  Drug Discov Today       Date:  2010-01-29       Impact factor: 7.851

3.  Polyubiquitin substrates allosterically activate their own degradation by the 26S proteasome.

Authors:  Dawadschargal Bech-Otschir; Annett Helfrich; Cordula Enenkel; Gesa Consiglieri; Michael Seeger; Hermann-Georg Holzhütter; Burkhardt Dahlmann; Peter-Michael Kloetzel
Journal:  Nat Struct Mol Biol       Date:  2009-01-25       Impact factor: 15.369

Review 4.  Dynamic regulation of ubiquitin-dependent cell cycle control.

Authors:  Allison Craney; Michael Rape
Journal:  Curr Opin Cell Biol       Date:  2013-07-24       Impact factor: 8.382

5.  Assembly of the 26S proteasome is regulated by phosphorylation of the p45/Rpt6 ATPase subunit.

Authors:  K Satoh; H Sasajima; K I Nyoumura; H Yokosawa; H Sawada
Journal:  Biochemistry       Date:  2001-01-16       Impact factor: 3.162

6.  O-GlcNAc modification is an endogenous inhibitor of the proteasome.

Authors:  Fengxue Zhang; Kaihong Su; Xiaoyong Yang; Damon B Bowe; Andrew J Paterson; Jeffrey E Kudlow
Journal:  Cell       Date:  2003-12-12       Impact factor: 41.582

7.  Regulation of the proteasome by neuronal activity and calcium/calmodulin-dependent protein kinase II.

Authors:  Stevan N Djakovic; Lindsay A Schwarz; Barbara Barylko; George N DeMartino; Gentry N Patrick
Journal:  J Biol Chem       Date:  2009-07-28       Impact factor: 5.157

Review 8.  Gates, Channels, and Switches: Elements of the Proteasome Machine.

Authors:  Daniel Finley; Xiang Chen; Kylie J Walters
Journal:  Trends Biochem Sci       Date:  2015-11-28       Impact factor: 13.807

9.  Enhancement of proteasome activity by a small-molecule inhibitor of USP14.

Authors:  Byung-Hoon Lee; Min Jae Lee; Soyeon Park; Dong-Chan Oh; Suzanne Elsasser; Ping-Chung Chen; Carlos Gartner; Nevena Dimova; John Hanna; Steven P Gygi; Scott M Wilson; Randall W King; Daniel Finley
Journal:  Nature       Date:  2010-09-09       Impact factor: 49.962

10.  Site-specific proteasome phosphorylation controls cell proliferation and tumorigenesis.

Authors:  Xing Guo; Xiaorong Wang; Zhiping Wang; Sourav Banerjee; Jing Yang; Lan Huang; Jack E Dixon
Journal:  Nat Cell Biol       Date:  2015-12-14       Impact factor: 28.824
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  3 in total

1.  Targeting dual-specificity tyrosine phosphorylation-regulated kinase 2 with a highly selective inhibitor for the treatment of prostate cancer.

Authors:  Kai Yuan; Zhaoxing Li; Wenbin Kuang; Xiao Wang; Minghui Ji; Weijiao Chen; Jiayu Ding; Jiaxing Li; Wenjian Min; Chengliang Sun; Xiuquan Ye; Meiling Lu; Liping Wang; Haixia Ge; Yuzhang Jiang; Haiping Hao; Yibei Xiao; Peng Yang
Journal:  Nat Commun       Date:  2022-05-25       Impact factor: 17.694

2.  A KLF4-DYRK2-mediated pathway regulating self-renewal in CML stem cells.

Authors:  Chun Shik Park; Andrew H Lewis; Taylor J Chen; Cory S Bridges; Ye Shen; Koramit Suppipat; Monica Puppi; Julie A Tomolonis; Paul D Pang; Toni-Ann Mistretta; Leyuan Ma; Michael R Green; Rachel Rau; H Daniel Lacorazza
Journal:  Blood       Date:  2019-11-28       Impact factor: 25.476

Review 3.  Reversible phosphorylation of the 26S proteasome.

Authors:  Xing Guo; Xiuliang Huang; Mark J Chen
Journal:  Protein Cell       Date:  2017-03-03       Impact factor: 14.870
  3 in total

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