| Literature DB >> 26818601 |
Xuan Wang1, Lauren A Beste2, Marissa M Maier3, Xiao-Hua Zhou1,4.
Abstract
In observational studies, estimation of average causal treatment effect on a patient's response should adjust for confounders that are associated with both treatment exposure and response. In addition, the response, such as medical cost, may have incomplete follow-up. In this article, a double robust estimator is proposed for average causal treatment effect for right censored medical cost data. The estimator is double robust in the sense that it remains consistent when either the model for the treatment assignment or the regression model for the response is correctly specified. Double robust estimators increase the likelihood the results will represent a valid inference. Asymptotic normality is obtained for the proposed estimator, and an estimator for the asymptotic variance is also derived. Simulation studies show good finite sample performance of the proposed estimator and a real data analysis using the proposed method is provided as illustration.Entities:
Keywords: average causal treatment effect; censored data; double robust estimator; inverse probability weighted; lifetime medical cost data
Mesh:
Year: 2016 PMID: 26818601 DOI: 10.1002/sim.6876
Source DB: PubMed Journal: Stat Med ISSN: 0277-6715 Impact factor: 2.373