Literature DB >> 26818467

Host derived biomarkers of inflammation, apoptosis, and endothelial activation are associated with clinical outcomes in patients with bacteremia and sepsis regardless of microbial etiology.

William O Hahn1, Carmen Mikacenic2, Brenda L Price3, Susanna Harju-Baker2, Ronit Katz4, Jonathan Himmelfarb4, Mark M Wurfel2, W Conrad Liles1.   

Abstract

Entities:  

Keywords:  G-CSF; IL-6; IL-8; TNFR-1; angiopoietin-1; angiopoietin-2; bacteremia; gram-negative; gram-positive; sFAS; sVAM-1; sepsis

Mesh：

Substances：

Year:  2016        PMID： 26818467      PMCID： PMC4871669          DOI： 10.1080/21505594.2016.1144003

Source DB:  PubMed          Journal:  Virulence        ISSN： 2150-5594            Impact factor:   5.882


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  45 in total

1.  Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans.

Authors:  R S Hotchkiss; K W Tinsley; P E Swanson; R E Schmieg; J J Hui; K C Chang; D F Osborne; B D Freeman; J P Cobb; T G Buchman; I E Karl
Journal:  J Immunol       Date:  2001-06-01       Impact factor: 5.422

Review 2.  Biomarkers: diagnosis and risk assessment in sepsis.

Authors:  Corey E Ventetuolo; Mitchell M Levy
Journal:  Clin Chest Med       Date:  2008-12       Impact factor: 2.878

3.  Accelerated lymphocyte death in sepsis occurs by both the death receptor and mitochondrial pathways.

Authors:  Richard S Hotchkiss; Stephen B Osmon; Katherine C Chang; Tracey H Wagner; Craig M Coopersmith; Irene E Karl
Journal:  J Immunol       Date:  2005-04-15       Impact factor: 5.422

4.  Genetic variation in the FAS gene and associations with acute lung injury.

Authors:  Bradford J Glavan; Tarah D Holden; Christopher H Goss; R Anthony Black; Margaret J Neff; Avery B Nathens; Thomas R Martin; Mark M Wurfel
Journal:  Am J Respir Crit Care Med       Date:  2010-09-02       Impact factor: 21.405

5.  Chronic sepsis mortality characterized by an individualized inflammatory response.

Authors:  Marcin F Osuchowski; Kathy Welch; Huan Yang; Javed Siddiqui; Daniel G Remick
Journal:  J Immunol       Date:  2007-07-01       Impact factor: 5.422

6.  The sepsis seesaw: tilting toward immunosuppression.

Authors:  Richard S Hotchkiss; Craig M Coopersmith; Jonathan E McDunn; Thomas A Ferguson
Journal:  Nat Med       Date:  2009-05       Impact factor: 53.440

7.  Comparison of the immunostimulatory and proinflammatory activities of candidate Gram-positive endotoxins, lipoteichoic acid, peptidoglycan, and lipopeptides, in murine and human cells.

Authors:  Matthew R Kimbrell; Hemamali Warshakoon; Jens R Cromer; Subbalakshmi Malladi; Jennifer D Hood; Rajalakshmi Balakrishna; Tandace A Scholdberg; Sunil A David
Journal:  Immunol Lett       Date:  2008-04-18       Impact factor: 3.685

8.  Gene-expression profiling of gram-positive and gram-negative sepsis in critically ill patients.

Authors:  Benjamin M P Tang; Anthony S McLean; Ian W Dawes; Stephen J Huang; Mark J Cowley; Ruby C Y Lin
Journal:  Crit Care Med       Date:  2008-04       Impact factor: 7.598

9.  Role of Toll-like receptor 4 in gram-positive and gram-negative pneumonia in mice.

Authors:  Judith Branger; Sylvia Knapp; Sebastiaan Weijer; Jaklien C Leemans; Jennie M Pater; Peter Speelman; Sandrine Florquin; Tom van der Poll
Journal:  Infect Immun       Date:  2004-02       Impact factor: 3.441

10.  Regulation of Fas (APO-1, CD95) and Fas ligand expression in leukocytes during systemic inflammation in humans.

Authors:  Claudia Marsik; Thomas Halama; Francesco Cardona; Wilhelm Wlassits; Florian Mayr; Johannes Pleiner; Bernd Jilma
Journal:  Shock       Date:  2003-12       Impact factor: 3.454
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  14 in total

1.  Higher Plasma Endothelial Markers in Adults with Cystic Fibrosis Compared with Healthy Age-matched Control Subjects.

Authors:  Pavan K Bhatraju; Katie B Hisert; Moira L Aitken; Christopher H Goss; W Conrad Liles; William A Altemeier
Journal:  Ann Am Thorac Soc       Date:  2019-06

2.  Fever in returning travellers and migrants: disease severity markers to improve triage and management.

Authors:  Michelle Ngai; Kevin C Kain
Journal:  J Travel Med       Date:  2020-09-26       Impact factor: 8.490

3.  Biomarkers of endothelial activation/dysfunction distinguish sub-groups of Ugandan patients with sepsis and differing mortality risks.

Authors:  Danielle V Clark; Patrick Banura; Karen Bandeen-Roche; W Conrad Liles; Kevin C Kain; W Michael Scheld; William J Moss; Shevin T Jacob
Journal:  JCI Insight       Date:  2019-04-23

4.  A Two-Biomarker Model Predicts Mortality in the Critically Ill with Sepsis.

Authors:  Carmen Mikacenic; Brenda L Price; Susanna Harju-Baker; D Shane O'Mahony; Cassianne Robinson-Cohen; Frank Radella; William O Hahn; Ronit Katz; David C Christiani; Jonathan Himmelfarb; W Conrad Liles; Mark M Wurfel
Journal:  Am J Respir Crit Care Med       Date:  2017-10-15       Impact factor: 21.405

5.  Posterior Reversible Encephalopathy in Sepsis-Associated Encephalopathy: Experience from a Single Center.

Authors:  Günseli Orhun; Serra Sencer; Erdem Tüzün; Nerses Bebek; Perihan Ergin Özcan; Mehmet Barburoğlu; Mehmet Güven Günver; Figen Esen
Journal:  Neurocrit Care       Date:  2022-02-08       Impact factor: 3.532

6.  Tie1: an orphan receptor provides context for angiopoietin-2/Tie2 signaling.

Authors:  Sarah B Mueller; Christopher D Kontos
Journal:  J Clin Invest       Date:  2016-08-22       Impact factor: 14.808

7.  Clinician-initiated research on treating the host response to pandemic influenza.

Authors:  David S Fedson
Journal:  Hum Vaccin Immunother       Date:  2017-10-31       Impact factor: 3.452

8.  Circulating levels of soluble Fas (sCD95) are associated with risk for development of a nonresolving acute kidney injury subphenotype.

Authors:  Pavan K Bhatraju; Cassianne Robinson-Cohen; Carmen Mikacenic; Susanna Harju-Baker; Victoria Dmyterko; Natalie S J Slivinski; W Conrad Liles; Jonathan Himmelfarb; Susan R Heckbert; Mark M Wurfel
Journal:  Crit Care       Date:  2017-08-17       Impact factor: 9.097

9.  sTREM-1 predicts mortality in hospitalized patients with infection in a tropical, middle-income country.

Authors:  Shelton W Wright; Lara Lovelace-Macon; Viriya Hantrakun; Kristina E Rudd; Prapit Teparrukkul; Susanna Kosamo; W Conrad Liles; Direk Limmathurotsakul; T Eoin West
Journal:  BMC Med       Date:  2020-07-01       Impact factor: 8.775

Review 10.  Endothelial Activation: The Ang/Tie Axis in Sepsis.

Authors:  Aleksandra Leligdowicz; Melissa Richard-Greenblatt; Julie Wright; Valerie M Crowley; Kevin C Kain
Journal:  Front Immunol       Date:  2018-04-24       Impact factor: 7.561
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