Literature DB >> 18954695

Biomarkers: diagnosis and risk assessment in sepsis.

Corey E Ventetuolo1, Mitchell M Levy.   

Abstract

Prompt diagnosis, intervention, and risk assessment are critical in caring for septic patient but remain difficult with currently available methods. Biomarkers may become useful adjuncts to clinicians and ultimately serve as targets for future therapeutic trials in sepsis. The most relevant markers are reviewed in this article, including interleukin-6, C-reactive protein, procalcitonin, triggering receptor expressed on myeloid cells-1, and biomarker panels.

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Year:  2008        PMID: 18954695     DOI: 10.1016/j.ccm.2008.07.001

Source DB:  PubMed          Journal:  Clin Chest Med        ISSN: 0272-5231            Impact factor:   2.878


  29 in total

1.  Host derived biomarkers of inflammation, apoptosis, and endothelial activation are associated with clinical outcomes in patients with bacteremia and sepsis regardless of microbial etiology.

Authors:  William O Hahn; Carmen Mikacenic; Brenda L Price; Susanna Harju-Baker; Ronit Katz; Jonathan Himmelfarb; Mark M Wurfel; W Conrad Liles
Journal:  Virulence       Date:  2016-01-28       Impact factor: 5.882

2.  Altered levels of soluble CD18 may associate immune mechanisms with outcome in sepsis.

Authors:  T W Kragstrup; K Juul-Madsen; S H Christiansen; X Zhang; J Krog; T Vorup-Jensen; A G Kjaergaard
Journal:  Clin Exp Immunol       Date:  2017-08-07       Impact factor: 4.330

3.  Diagnosing sepsis: a step forward, and possibly a step back.

Authors:  Steven Q Simpson
Journal:  Ann Transl Med       Date:  2017-02

4.  Treatment with histone deacetylase inhibitor attenuates MAP kinase mediated liver injury in a lethal model of septic shock.

Authors:  Robert A Finkelstein; Yongqing Li; Baoling Liu; Fahad Shuja; Eugene Fukudome; George C Velmahos; Marc deMoya; Hasan B Alam
Journal:  J Surg Res       Date:  2010-05-10       Impact factor: 2.192

Review 5.  [Microarrays as biomarkers in trauma].

Authors:  V Bogner; W Mutschler
Journal:  Unfallchirurg       Date:  2014-08       Impact factor: 1.000

Review 6.  Sepsis: from pattern to mechanism and back.

Authors:  Gary An; Rami A Namas; Yoram Vodovotz
Journal:  Crit Rev Biomed Eng       Date:  2012

7.  Sepsis: Something old, something new, and a systems view.

Authors:  Rami Namas; Ruben Zamora; Rajaie Namas; Gary An; John Doyle; Thomas E Dick; Frank J Jacono; Ioannis P Androulakis; Gary F Nieman; Steve Chang; Timothy R Billiar; John A Kellum; Derek C Angus; Yoram Vodovotz
Journal:  J Crit Care       Date:  2011-07-27       Impact factor: 3.425

8.  DAMPs, PAMPs, and the origins of SIRS in bacterial sepsis.

Authors:  Lori F Gentile; Lyle L Moldawer
Journal:  Shock       Date:  2013-01       Impact factor: 3.454

9.  Authors's reply.

Authors:  Chamindie Punyadeera; E Marion Schneider; Dave Schaffer; Hsin-Yun Hsu; Thomas O Joos; Fabian Kriebel; Manfred Weiss; Wim F J Verhaegh
Journal:  J Emerg Trauma Shock       Date:  2010-07

10.  Myeloperoxidase instigates proinflammatory responses in a cecal ligation and puncture rat model of sepsis.

Authors:  Hong Yu; Yajun Liu; Meifang Wang; Ricardo J Restrepo; Derek Wang; Theodore J Kalogeris; William L Neumann; David A Ford; Ronald J Korthuis
Journal:  Am J Physiol Heart Circ Physiol       Date:  2020-08-07       Impact factor: 4.733

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