Literature DB >> 26817575

Prescription of Vitamin D to Fracture Patients: A Lack of Consensus and Evidence.

Sheila Sprague1, Mohit Bhandari, Tahira Devji, Taryn Scott, Brad Petrisor, Paula McKay, Gerard P Slobogean.   

Abstract

OBJECTIVES: We conducted a survey to explore practice patterns regarding the assessment of hypovitaminosis D and the prescription of vitamin D in acute fracture patients. Our secondary objective was to determine whether practice patterns differed between fragility and nonfragility fracture patients.
DESIGN: Cross-sectional survey.
SETTING: All surveys were completed using SurveyMonkey. PATIENTS/PARTICIPANTS: We surveyed surgeon members of the Canadian Orthopaedic Association and the Orthopaedic Trauma Association. INTERVENTION: Survey. MAIN OUTCOME MEASUREMENTS: The proportion of surgeons who routinely prescribe vitamin D to fracture patients.
RESULTS: A total of 397 surveys were completed. Of total, 65.8% of surgeons indicated that they routinely prescribe vitamin D to fragility fracture patients and 25.7% routinely prescribe vitamin D to nonfragility fracture patients. We identified considerable variability in dosing regimens, as 45 different dosing regimens were prescribed in fragility fracture patients and 29 in nonfragility fracture patients. They ranged from daily doses of 400 IU to loading doses of 600,000 IU. The most frequently prescribed doses were 1000 IU daily (14.6%), 2000 IU daily (13.4%), and 50,000 IU weekly (8.7%). Respondents indicated that they heavily relied on clinical experience to guide their decisions to prescribe vitamin D to fracture patients.
CONCLUSIONS: The results of this survey demonstrate multiple areas of uncertainty and a lack of consensus in the prescription of vitamin D to fracture patients. Fragility patients frequently receive vitamin D supplementation, whereas most surgeons do not prescribe vitamin D to young fracture patients. High-quality clinical research is needed to determine whether vitamin D supplementation is beneficial to fracture patients. LEVEL OF EVIDENCE: Therapeutic Level V. See Instructions for Authors for a complete description of levels of evidence.

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Year:  2016        PMID: 26817575     DOI: 10.1097/BOT.0000000000000451

Source DB:  PubMed          Journal:  J Orthop Trauma        ISSN: 0890-5339            Impact factor:   2.512


  9 in total

1.  Serum 25(OH)D is associated with an altered bone turnover marker response after a hip fracture.

Authors:  Christopher C Stewart; Nathan N O'Hara; Denise Orwig; Marc C Hochberg; Sheila Sprague; Jay Magaziner; Gerard P Slobogean
Journal:  J Orthop Res       Date:  2019-01-10       Impact factor: 3.494

Review 2.  Vitamin D history part III: the "modern times"-new questions for orthopaedic practice: deficiency, cell therapy, osteomalacia, fractures, supplementation, infections.

Authors:  Philippe Hernigou; Jordan Sitbon; Arnaud Dubory; Jean Charles Auregan
Journal:  Int Orthop       Date:  2019-04-29       Impact factor: 3.075

Review 3.  How can the orthopedic surgeon ensure optimal vitamin D status in patients operated for an osteoporotic fracture?

Authors:  T Chevalley; M L Brandi; E Cavalier; N C Harvey; G Iolascon; C Cooper; D Hannouche; J-F Kaux; A Kurth; S Maggi; G Maier; K Papavasiliou; N Al-Daghri; M Sosa-Henríquez; N Suhm; U Tarantino; J-Y Reginster; R Rizzoli
Journal:  Osteoporos Int       Date:  2021-05-20       Impact factor: 4.507

4.  A Missed Opportunity in Bone Health: Vitamin D and Calcium Use in Elderly Femoral Neck Fracture Patients Following Arthroplasty.

Authors:  Sheila Sprague; Kim Madden; Gerard Slobogean; Brad Petrisor; Jonathan D Rick Adachi; Earl Bogoch; Ydo V Kleinlugtenbelt; Mohit Bhandari
Journal:  Geriatr Orthop Surg Rehabil       Date:  2017-10-25

5.  Patient preferences for nutritional supplementation to improve fracture healing: a discrete choice experiment.

Authors:  Elizabeth Nichols; Nathan N O'Hara; Yasmin Degani; Sheila A Sprague; Jonathan D Adachi; Mohit Bhandari; Michael F Holick; Daniel W Connelly; Gerard P Slobogean
Journal:  BMJ Open       Date:  2018-04-12       Impact factor: 2.692

6.  Tobacco and bone fractures: A review of the facts and issues that every orthopaedic surgeon should know.

Authors:  J Hernigou; F Schuind
Journal:  Bone Joint Res       Date:  2019-07-05       Impact factor: 5.853

7.  Study protocol: design and rationale for an exploratory phase II randomized controlled trial to determine optimal vitamin D3 supplementation strategies for acute fracture healing.

Authors:  Sheila Sprague; Sofia Bzovsky; Daniel Connelly; Lehana Thabane; Jonathan D Adachi; Gerard P Slobogean
Journal:  Pilot Feasibility Stud       Date:  2019-11-22

8.  Preoperative Vitamin D Deficiency is Associated with Postoperative Functional Recovery and Complications after Hip Fracture Surgery.

Authors:  Chaemoon Lim; Young Ho Roh; Saeil Kim; Kwang Woo Nam
Journal:  J Bone Metab       Date:  2021-11-30

9.  Bone turnover markers as surrogates of fracture healing after intramedullary fixation of tibia and femur fractures.

Authors:  Christopher C Stewart; Nathan N O'Hara; Sofia Bzovsky; Chelsea S Bahney; Sheila Sprague; Gerard P Slobogean
Journal:  Bone Joint Res       Date:  2022-04       Impact factor: 4.410

  9 in total

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