Basheer Tashtoush1, Roya Memarpour2, Jose Gonzalez1, James Benjamin Gleason1, Anas Hadeh3. 1. Fellow, Department of Pulmonary and Critical Care Medicine, Cleveland Clinic , Florida, 2950 Cleveland Clinic Blvd. 33331, Weston, Florida, USA . 2. Research Fellow, Department of Pulmonary and Critical Care Medicine, Cleveland Clinic , Florida, 2950 Cleveland Clinic Blvd. 33331, Weston, Florida, USA . 3. Attending Physician, Department of Pulmonary and Critical Care Medicine, Cleveland Clinic , Florida, 2950 Cleveland Clinic Blvd. 33331, Weston, Florida, USA .
Abstract
INTRODUCTION: Pulmonary sequestration also known as bronchopulmonary sequestration is a rare disease, with very few case series reviewed in literature. In this study, we review the demographics, presentation, imaging and treatment of pulmonary sequestration in 29 patients from our institution, and provide comparison data from previously published series with an overview of the disease history. MATERIALS AND METHODS: Records reviewed for all patients evaluated and treated in our institution with a pathological proven diagnosis of pulmonary sequestration from January 2004 through December 2013. Collected data included demographics, clinical presentation, diagnostic imaging, location of the lesion, type of sequestration, and subsequent treatment. RESULTS: Of the 29 patients reviewed 8 (28%) were children 0-2 years, 1 adolescent age 17, and 20 (69%) adults 21-70 years with a mean age of 42 among adults. Systemic arterial supply to the sequestered segment was demonstrated with computed tomographic angiography (CTA) in 25 patients (86%). In 19 patients (66%), the sequestered segment was located in the left lower lobe, and 16 (55%) were intralobar. CONCLUSION: Diagnostic delays of pulmonary sequestration were common among the adult population as the presenting symptoms often mimicked other common pulmonary diseases, such as pneumonia and asthma. These findings were consistent among previously published series. CTA was the preferred imaging modality for preoperative planning with high sensitivity and specificity in identifying the lesion.
INTRODUCTION: Pulmonary sequestration also known as bronchopulmonary sequestration is a rare disease, with very few case series reviewed in literature. In this study, we review the demographics, presentation, imaging and treatment of pulmonary sequestration in 29 patients from our institution, and provide comparison data from previously published series with an overview of the disease history. MATERIALS AND METHODS: Records reviewed for all patients evaluated and treated in our institution with a pathological proven diagnosis of pulmonary sequestration from January 2004 through December 2013. Collected data included demographics, clinical presentation, diagnostic imaging, location of the lesion, type of sequestration, and subsequent treatment. RESULTS: Of the 29 patients reviewed 8 (28%) were children 0-2 years, 1 adolescent age 17, and 20 (69%) adults 21-70 years with a mean age of 42 among adults. Systemic arterial supply to the sequestered segment was demonstrated with computed tomographic angiography (CTA) in 25 patients (86%). In 19 patients (66%), the sequestered segment was located in the left lower lobe, and 16 (55%) were intralobar. CONCLUSION: Diagnostic delays of pulmonary sequestration were common among the adult population as the presenting symptoms often mimicked other common pulmonary diseases, such as pneumonia and asthma. These findings were consistent among previously published series. CTA was the preferred imaging modality for preoperative planning with high sensitivity and specificity in identifying the lesion.
Authors: O Yucel; S Gurkok; A Gozubuyuk; H Caylak; E Sapmaz; K Kavakli; M Dakak; O Genc Journal: Thorac Cardiovasc Surg Date: 2008-04 Impact factor: 1.827
Authors: D Van Raemdonck; K De Boeck; H Devlieger; M Demedts; P Moerman; W Coosemans; G Deneffe; T Lerut Journal: Eur J Cardiothorac Surg Date: 2001-04 Impact factor: 4.191