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Literature DB >> 26816082

Microtubule-Tau Interaction as a Therapeutic Target for Alzheimer's Disease.

Yanina Ivashko Pachima¹, Liu-yao Zhou², Peng Lei^3,4, Illana Gozes⁵.

Abstract

Entities: Disease Gene

Mesh：

Substances：

Year: 2016 PMID： 26816082 DOI： 10.1007/s12031-016-0715-x

Source DB: PubMed Journal: J Mol Neurosci ISSN： 0895-8696 Impact factor: 3.444

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129 in total

1. Translation in vitro of rat brain messenger RNA coding for tubulin and actin.

Authors: I Gozes; H Schmitt; U Z Littauer
Journal: Proc Natl Acad Sci U S A Date: 1975-02 Impact factor: 11.205

2. Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model.

Authors: Bin Zhang; Arpita Maiti; Sharon Shively; Fara Lakhani; Gaye McDonald-Jones; Jennifer Bruce; Edward B Lee; Sharon X Xie; Sonali Joyce; Chi Li; Philip M Toleikis; Virginia M-Y Lee; John Q Trojanowski
Journal: Proc Natl Acad Sci U S A Date: 2004-12-22 Impact factor: 11.205

3. The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity.

Authors: Nichole E LaPointe; Gerardo Morfini; Gustavo Pigino; Irina N Gaisina; Alan P Kozikowski; Lester I Binder; Scott T Brady
Journal: J Neurosci Res Date: 2009-02 Impact factor: 4.164

Review 4. Protection against tauopathy by the drug candidates NAP (davunetide) and D-SAL: biochemical, cellular and behavioral aspects.

Authors: Natalia Shiryaev; Regina Pikman; Eliezer Giladi; Illana Gozes
Journal: Curr Pharm Des Date: 2011 Impact factor: 3.116

5. Tubulin microheterogeneity increases with rat brain maturation.

Authors: I Gozes; U Z Littauer
Journal: Nature Date: 1978-11-23 Impact factor: 49.962

6. Sexual divergence in microtubule function: the novel intranasal microtubule targeting SKIP normalizes axonal transport and enhances memory.

Authors: N Amram; G Hacohen-Kleiman; S Sragovich; A Malishkevich; J Katz; O Touloumi; R Lagoudaki; N C Grigoriadis; E Giladi; A Yeheskel; M Pasmanik-Chor; Y Jouroukhin; I Gozes
Journal: Mol Psychiatry Date: 2016-01-19 Impact factor: 15.992

7. Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease.

Authors: Jean C Augustinack; Anja Schneider; Eva-Maria Mandelkow; Bradley T Hyman
Journal: Acta Neuropathol Date: 2002-01 Impact factor: 17.088

Review 8. Tau phosphorylation: the therapeutic challenge for neurodegenerative disease.

Authors: Diane P Hanger; Brian H Anderton; Wendy Noble
Journal: Trends Mol Med Date: 2009-02-24 Impact factor: 11.951

9. Interaction of tau protein with the dynactin complex.

Authors: Enrico Magnani; Juan Fan; Laura Gasparini; Matthew Golding; Meredith Williams; Giampietro Schiavo; Michel Goedert; Linda A Amos; Maria Grazia Spillantini
Journal: EMBO J Date: 2007-10-11 Impact factor: 11.598

10. Tau and caspase 3 as targets for neuroprotection.

Authors: Anat Idan-Feldman; Regina Ostritsky; Illana Gozes
Journal: Int J Alzheimers Dis Date: 2012-05-30

5 in total

1. Simulating tubulin-associated unit transport in an axon: using bootstrapping for estimating confidence intervals of best-fit parameter values obtained from indirect experimental data.

Authors: I A Kuznetsov; A V Kuznetsov
Journal: Proc Math Phys Eng Sci Date: 2017-05-03 Impact factor: 2.704