S Y Chabok1, H Yazdanshenas2, A F Naeeni3, A Ziabakhsh4, S S Bidar5, A Reihanian6, S Bazargan-Hejazi7,8. 1. Guilan University of Medical Sciences, Rasht, Iran. sh.yousefzadeh@gmail.com. 2. Charles R. Drew University of Medicine and Science, College of Medicine, Los Angeles, CA, USA. Hamedyazdanshenas@cdrewu.edu. 3. Guilan University of Medical Sciences, Rasht, Iran. fadaenaeeni@yahoo.com. 4. Road Trauma Research Center, Guilan University of Medical Sciences, Rasht, Iran. aziabakhsh@yahoo.com. 5. Tehran University of Medical Sciences, Tehran, Iran. s.shabbidar@yahoo.com. 6. Road Trauma Research Center, Guilan University of Medical Sciences, Rasht, Iran. atossa73@yahoo.com. 7. Charles R. Drew University, College of Medicine, 1731 East 120th Street, Los Angeles, CA, 90059, USA. shahrzadbazargan@cdrewu.edu. 8. David Geffen School of Medicine, University of California, Los Angeles, USA. shahrzadbazargan@cdrewu.edu.
Abstract
PURPOSE: Obesity is a risk factor in treatment outcomes of critically ill patients. This study was conducted to determine the impact of obesity on the likelihood of recovery from traumatic brain injury (TBI) in intensive care unit (ICU) patients. METHODS: We carried out a prospective study on 115 head injury patients who were admitted to the ICU of Poursina Hospital, Rasht, in the one-year period between July 2006 and June 2007. Obese patients (body mass index [BMI] ≥ 30 kg/m(2)) were compared with non-obese patients (BMI < 30 kg/m(2)). Demographic information, acute physiology and chronic health evaluation scores, Injury Severity Scores (ISS), Glasgow Coma Scale scores, and ICU mortality incidences were recorded. RESULTS: Obese patients had significantly higher ICU mortality rates compared to non-obese patients (p = 0.02). Furthermore, we observed a trend towards a higher ICU mortality rate in obese patients with ISS > 25 (p = 0.04). Moreover, obesity was associated with prolonged mechanical ventilation, ICU length of stay (ILOS), and hospital length of stay (HLOS) (p < 0.001). CONCLUSIONS: Obesity was associated with increased ICU mortality and prolonged dependency on mechanical ventilation, ILOS, and HLOS in patients with TBI. However, further prospective studies with larger sample sizes are needed to substantiate these findings.
PURPOSE:Obesity is a risk factor in treatment outcomes of critically illpatients. This study was conducted to determine the impact of obesity on the likelihood of recovery from traumatic brain injury (TBI) in intensive care unit (ICU) patients. METHODS: We carried out a prospective study on 115 head injurypatients who were admitted to the ICU of Poursina Hospital, Rasht, in the one-year period between July 2006 and June 2007. Obesepatients (body mass index [BMI] ≥ 30 kg/m(2)) were compared with non-obesepatients (BMI < 30 kg/m(2)). Demographic information, acute physiology and chronic health evaluation scores, Injury Severity Scores (ISS), Glasgow Coma Scale scores, and ICU mortality incidences were recorded. RESULTS:Obesepatients had significantly higher ICU mortality rates compared to non-obesepatients (p = 0.02). Furthermore, we observed a trend towards a higher ICU mortality rate in obesepatients with ISS > 25 (p = 0.04). Moreover, obesity was associated with prolonged mechanical ventilation, ICU length of stay (ILOS), and hospital length of stay (HLOS) (p < 0.001). CONCLUSIONS:Obesity was associated with increased ICU mortality and prolonged dependency on mechanical ventilation, ILOS, and HLOS in patients with TBI. However, further prospective studies with larger sample sizes are needed to substantiate these findings.
Entities:
Keywords:
Body mass index; Hospital length of stay; ICU; ICU length of stay; Mortality; Obesity; Traumatic brain injury
Authors: A Anzueto; F Frutos-Vivar; A Esteban; N Bensalami; D Marks; K Raymondos; C Apezteguía; Y Arabi; J Hurtado; M González; V Tomicic; F Abroug; J Elizalde; N Cakar; P Pelosi; N D Ferguson Journal: Thorax Date: 2010-10-27 Impact factor: 9.139
Authors: Grant V Bochicchio; Manjari Joshi; Kelly Bochicchio; Shelly Nehman; J Kathleen Tracy; Thomas M Scalea Journal: J Am Coll Surg Date: 2006-09-01 Impact factor: 6.113
Authors: David H Livingston; Robert F Lavery; Anne N'kanza; Devashish Anjaria; Ziad C Sifri; Alicia M Mohr; Anne C Mosenthal Journal: Am Surg Date: 2013-03 Impact factor: 0.688
Authors: Erin D Bigler; Tracy J Abildskov; Barry Eggleston; Brian A Taylor; David F Tate; Jo Ann Petrie; Mary R Newsome; Randall S Scheibel; Harvey Levin; William C Walker; Naomi Goodrich-Hunsaker; Nicholas J Tustison; James R Stone; Andrew R Mayer; Timothy D Duncan; Gerry E York; Elisabeth A Wilde Journal: Int J Methods Psychiatr Res Date: 2019-05-23 Impact factor: 4.035
Authors: Jasmeet P Hayes; Meghan E Pierce; Kate E Valerio; Mark W Miller; Bertrand Russell Huber; Catherine B Fortier; Jennifer R Fonda; William Milberg; Regina McGlinchey Journal: Neuropsychopharmacology Date: 2021-08-16 Impact factor: 8.294
Authors: Lisa Ronan; Aaron F Alexander-Bloch; Konrad Wagstyl; Sadaf Farooqi; Carol Brayne; Lorraine K Tyler; Paul C Fletcher Journal: Neurobiol Aging Date: 2016-07-27 Impact factor: 4.673