Literature DB >> 26812522

Rates of organ donation in a UK tertiary cardiac arrest centre following out-of-hospital cardiac arrest.

Olivia V Cheetham1, Matthew J C Thomas2, John Hadfield3, Fran O'Higgins3, Claire Mitchell3, Kieron D Rooney2.   

Abstract

AIM: To ascertain the rate of successful organ donation (OD) within patients who sustained an out of hospital cardiac arrest (OHCA) with initial return of spontaneous circulation (ROSC) and survival to hospital admission, but whom subsequently do not survive to hospital discharge.
METHODS: A retrospective audit of ambulance service and hospital databases from January 2010 to January 2015 was undertaken in a United Kingdom tertiary-referral regional cardiac arrest centre. Crude denominator data for cardiac arrests was obtained from the regional ambulance service; the ICU database was interrogated for OHCA patient admissions and outcomes. Patients who died were cross-referenced against the local Organ Donation service database.
RESULTS: Five hundred and fourteen {514} patients were admitted to ICU following OHCA over this five year period. Two hundred and forty-one {241} patients (47%) survived to hospital discharge and 273 (53%) died of whom 106 (39%) were referred to a Specialist Nurse for Organ Donation (SNOD). The conversion rate after the family was approached was 64%. Twenty-eight {28} patients proceeded to donation and 25 patients (24%) successfully donated at least one organ. On average, a patient proceeding to donation provided 1.9 organs.
CONCLUSIONS: A proactive, systematic approach to OD in OHCA patients can provide a good conversion rate and substantial number of donors. Most donations occur after death from circulatory criteria. There is a positive socio-economic benefit with nearly £4m in savings to the health service within the next 5 years potentially being realised during this period by liberating patients from dialysis.
Copyright © 2016. Published by Elsevier Ireland Ltd.

Entities:  

Keywords:  Cardiac arrest; Organ donation; Organ procurement; Resuscitation

Mesh:

Year:  2016        PMID: 26812522     DOI: 10.1016/j.resuscitation.2016.01.003

Source DB:  PubMed          Journal:  Resuscitation        ISSN: 0300-9572            Impact factor:   5.262


  8 in total

1.  Organ donation after out-of-hospital cardiac arrest: a population-based study of data from the Paris Sudden Death Expertise Center.

Authors:  M Renaudier; Y Binois; F Dumas; L Lamhaut; F Beganton; D Jost; J Charpentier; O Lesieur; E Marijon; X Jouven; A Cariou; W Bougouin
Journal:  Ann Intensive Care       Date:  2022-06-06       Impact factor: 10.318

2.  Organ donation after resuscitation from cardiac arrest.

Authors:  Jonathan Elmer; Bradley J Molyneaux; Kurt Shutterly; Susan A Stuart; Clifton W Callaway; Joseph M Darby; Amy R Weisgerber
Journal:  Resuscitation       Date:  2019-10-22       Impact factor: 5.262

Review 3.  The rate of brain death and organ donation in patients resuscitated from cardiac arrest: a systematic review and meta-analysis.

Authors:  Claudio Sandroni; Sonia D'Arrigo; Clifton W Callaway; Alain Cariou; Irina Dragancea; Fabio Silvio Taccone; Massimo Antonelli
Journal:  Intensive Care Med       Date:  2016-10-03       Impact factor: 17.440

Review 4.  Machine Perfusion for Extended Criteria Donor Livers: What Challenges Remain?

Authors:  Jeannette Widmer; Janina Eden; Mauricio Flores Carvalho; Philipp Dutkowski; Andrea Schlegel
Journal:  J Clin Med       Date:  2022-09-03       Impact factor: 4.964

5.  Extracorporeal Membrane Oxygenation for Cardiac Indications in Adults: A Health Technology Assessment.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2020-03-06

Review 6.  [Ethics of resuscitation and end of life decisions].

Authors:  Spyros D Mentzelopoulos; Keith Couper; Patrick Van de Voorde; Patrick Druwé; Marieke Blom; Gavin D Perkins; Ileana Lulic; Jana Djakow; Violetta Raffay; Gisela Lilja; Leo Bossaert
Journal:  Notf Rett Med       Date:  2021-06-02       Impact factor: 0.826

7.  Impact of Donor Pre-Procurement Cardiac Arrest (PPCA) on Clinical Outcomes in Liver Transplantation.

Authors:  Richard S Mangus; Joel R Schroering; Jonathan A Fridell; Chandrashekhar A Kubal
Journal:  Ann Transplant       Date:  2018-11-20       Impact factor: 1.530

8.  Occurrence and timing of withdrawal of life-sustaining measures in traumatic brain injury patients: a CENTER-TBI study.

Authors:  Ernest van Veen; Mathieu van der Jagt; Giuseppe Citerio; Nino Stocchetti; Diederik Gommers; Alex Burdorf; David K Menon; Andrew I R Maas; Erwin J O Kompanje; Hester F Lingsma
Journal:  Intensive Care Med       Date:  2021-08-05       Impact factor: 17.440

  8 in total

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