Literature DB >> 26810812

The potential of DISC1 protein as a therapeutic target for mental illness.

Akira Sawa1, Koko Ishizuka1, Nicholas Katsanis2.   

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Year:  2016        PMID： 26810812      PMCID： PMC5476421          DOI： 10.1517/14728222.2016.1146694

Source DB:  PubMed          Journal:  Expert Opin Ther Targets        ISSN： 1472-8222            Impact factor:   6.902


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  15 in total

1.  Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.

Authors:  D H Blackwood; A Fordyce; M T Walker; D M St Clair; D J Porteous; W J Muir
Journal:  Am J Hum Genet       Date:  2001-07-06       Impact factor: 11.025

Review 2.  Dendritic spine pathology in neuropsychiatric disorders.

Authors:  Peter Penzes; Michael E Cahill; Kelly A Jones; Jon-Eric VanLeeuwen; Kevin M Woolfrey
Journal:  Nat Neurosci       Date:  2011-03       Impact factor: 24.884

3.  A dopamine D2 receptor-DISC1 protein complex may contribute to antipsychotic-like effects.

Authors:  Ping Su; Shupeng Li; Sheng Chen; Tatiana V Lipina; Min Wang; Terence K Y Lai; Frankie H F Lee; Hailong Zhang; Dongxu Zhai; Stephen S G Ferguson; José N Nobrega; Albert H C Wong; John C Roder; Paul J Fletcher; Fang Liu
Journal:  Neuron       Date:  2014-11-26       Impact factor: 17.173

Review 4.  Linking neurodevelopmental and synaptic theories of mental illness through DISC1.

Authors:  Nicholas J Brandon; Akira Sawa
Journal:  Nat Rev Neurosci       Date:  2011-11-18       Impact factor: 34.870

5.  Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice.

Authors:  Hiroko Koike; P Alexander Arguello; Mirna Kvajo; Maria Karayiorgou; Joseph A Gogos
Journal:  Proc Natl Acad Sci U S A       Date:  2006-02-16       Impact factor: 11.205

6.  DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms.

Authors:  Kenji Nakata; Barbara K Lipska; Thomas M Hyde; Tianzhang Ye; Erin N Newburn; Yukitaka Morita; Radhakrishna Vakkalanka; Maxim Barenboim; Yoshitatsu Sei; Daniel R Weinberger; Joel E Kleinman
Journal:  Proc Natl Acad Sci U S A       Date:  2009-09-02       Impact factor: 11.205

7.  PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence.

Authors:  Akiko Hayashi-Takagi; Yoichi Araki; Mayumi Nakamura; Benedikt Vollrath; Sergio G Duron; Zhen Yan; Haruo Kasai; Richard L Huganir; David A Campbell; Akira Sawa
Journal:  Proc Natl Acad Sci U S A       Date:  2014-04-03       Impact factor: 11.205

Review 8.  DISC1 as a therapeutic target for mental illnesses.

Authors:  Takatoshi Hikida; Nao J Gamo; Akira Sawa
Journal:  Expert Opin Ther Targets       Date:  2012-11-06       Impact factor: 6.902

Review 9.  DISC1-binding proteins in neural development, signalling and schizophrenia.

Authors:  Nicholas J Bradshaw; David J Porteous
Journal:  Neuropharmacology       Date:  2010-12-31       Impact factor: 5.250

10.  Ciliopathy proteins regulate paracrine signaling by modulating proteasomal degradation of mediators.

Authors:  Yangfan P Liu; I-Chun Tsai; Manuela Morleo; Edwin C Oh; Carmen C Leitch; Filomena Massa; Byung-Hoon Lee; David S Parker; Daniel Finley; Norann A Zaghloul; Brunella Franco; Nicholas Katsanis
Journal:  J Clin Invest       Date:  2014-04-01       Impact factor: 14.808
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  4 in total

1.  BDNF overexpression prevents cognitive deficit elicited by adolescent cannabis exposure and host susceptibility interaction.

Authors:  Hadar Segal-Gavish; Neta Gazit; Yael Barhum; Tali Ben-Zur; Michal Taler; Shay Henry Hornfeld; Irit Gil-Ad; Abraham Weizman; Inna Slutsky; Minae Niwa; Atsushi Kamiya; Akira Sawa; Daniel Offen; Ran Barzilay
Journal:  Hum Mol Genet       Date:  2017-07-01       Impact factor: 6.150

2.  Disrupted-in-schizophrenia 1 functional polymorphisms and D2 /D3 receptor availability: A [11 C]-(+)-PHNO imaging study.

Authors:  Tarik Dahoun; Matthew M Nour; Rick A Adams; Svenja Trossbach; Sang H Lee; Hamel Patel; Charles Curtis; Carsten Korth; Oliver D Howes
Journal:  Genes Brain Behav       Date:  2019-07-05       Impact factor: 3.708

Review 3.  The impact of Disrupted-in-Schizophrenia 1 (DISC1) on the dopaminergic system: a systematic review.

Authors:  T Dahoun; S V Trossbach; N J Brandon; C Korth; O D Howes
Journal:  Transl Psychiatry       Date:  2017-01-31       Impact factor: 6.222

Review 4.  The TRAX, DISC1, and GSK3 complex in mental disorders and therapeutic interventions.

Authors:  Yu-Ting Weng; Ting Chien; I-I Kuan; Yijuang Chern
Journal:  J Biomed Sci       Date:  2018-10-04       Impact factor: 8.410
  4 in total

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