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Literature DB >> 26807758

Inflammation, fibrosis, and modulation of the process by mesenchymal stem/stromal cells.

Abstract

Fibrosis and scarring are the end stage of many disease processes. In effect, the collagen fibers that initially provide a necessary strength during the repair of injured tissues are frequently synthesized in excessive amounts and become irreversible fibrotic deposits that limit regeneration of the endogenous cells of a tissue. This review will focus on the potential of mesenchymal stem/stromal cells for treatment of fibrotic diseases, with emphasis on the role of TSG-6 as a mediator of anti-inflammatory effects.

Entities: Chemical Disease Gene Species

Keywords: Mesenchymal stem/stromal cells; Regenerative medicine; TSG-6; Tissue fibrosis

Mesh：

Substances：

Year: 2016 PMID： 26807758 PMCID： PMC4842094 DOI： 10.1016/j.matbio.2016.01.010

Source DB: PubMed Journal: Matrix Biol ISSN： 0945-053X Impact factor: 11.583

42 in total

1. Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury.

Authors: Mohammad Naimul Islam; Shonit R Das; Memet T Emin; Michelle Wei; Li Sun; Kristin Westphalen; David J Rowlands; Sadiqa K Quadri; Sunita Bhattacharya; Jahar Bhattacharya
Journal: Nat Med Date: 2012-04-15 Impact factor: 53.440

2. Density-Dependent Metabolic Heterogeneity in Human Mesenchymal Stem Cells.

Authors: Yijun Liu; Nathalie Muñoz; Bruce A Bunnell; Timothy M Logan; Teng Ma
Journal: Stem Cells Date: 2015-08-14 Impact factor: 6.277

3. Mitochondrial transfer between cells can rescue aerobic respiration.

Authors: Jeffrey L Spees; Scott D Olson; Mandolin J Whitney; Darwin J Prockop
Journal: Proc Natl Acad Sci U S A Date: 2006-01-23 Impact factor: 11.205

4. Retention of nonhelical procollagen containing cis-hydroxyproline in rough endoplasmic reticulum.

Authors: J Uitto; H Hoffman; D J Prockop
Journal: Science Date: 1975-12-19 Impact factor: 47.728

5. Expansion of adipose mesenchymal stromal cells is affected by human platelet lysate and plating density.

Authors: Dominik Cholewa; Thomas Stiehl; Anne Schellenberg; Gudrun Bokermann; Sylvia Joussen; Carmen Koch; Thomas Walenda; Norbert Pallua; Anna Marciniak-Czochra; Christoph V Suschek; Wolfgang Wagner
Journal: Cell Transplant Date: 2011-03-07 Impact factor: 4.064

Review 6. The resolution of inflammation: Principles and challenges.

Authors: Sarah E Headland; Lucy V Norling
Journal: Semin Immunol Date: 2015-04-22 Impact factor: 11.130

7. Anti-inflammatory protein TSG-6 reduces inflammatory damage to the cornea following chemical and mechanical injury.

Authors: Joo Youn Oh; Gavin W Roddy; Hosoon Choi; Ryang Hwa Lee; Joni H Ylöstalo; Robert H Rosa; Darwin J Prockop
Journal: Proc Natl Acad Sci U S A Date: 2010-09-13 Impact factor: 11.205

8. Phase-directed therapy: TSG-6 targeted to early inflammation improves bleomycin-injured lungs.

Authors: Andrea M Foskett; Nikolay Bazhanov; Xinyu Ti; April Tiblow; Thomas J Bartosh; Darwin J Prockop
Journal: Am J Physiol Lung Cell Mol Physiol Date: 2013-11-15 Impact factor: 5.464

Review 9. TSG-6: a pluripotent inflammatory mediator?

Authors: C M Milner; V A Higman; A J Day
Journal: Biochem Soc Trans Date: 2006-06 Impact factor: 5.407

10. Mesenchymal stem cells.

Authors: A I Caplan
Journal: J Orthop Res Date: 1991-09 Impact factor: 3.494

35 in total

Review 1. Decorin is a devouring proteoglycan: Remodeling of intracellular catabolism via autophagy and mitophagy.

Authors: Simone Buraschi; Thomas Neill; Renato V Iozzo
Journal: Matrix Biol Date: 2017-11-07 Impact factor: 11.583

Review 2. Extracellular matrix: The driving force of mammalian diseases.

Authors: Renato V Iozzo; Maria A Gubbiotti
Journal: Matrix Biol Date: 2018-04-03 Impact factor: 11.583

3. Mesenchymal Stromal Cells Inhibit Inflammatory Lymphangiogenesis in the Cornea by Suppressing Macrophage in a TSG-6-Dependent Manner.

Authors: Hyun Beom Song; Se Yeon Park; Jung Hwa Ko; Jong Woo Park; Chang Ho Yoon; Dong Hyun Kim; Jeong Hun Kim; Mee Kum Kim; Ryang Hwa Lee; Darwin J Prockop; Joo Youn Oh
Journal: Mol Ther Date: 2017-10-05 Impact factor: 11.454

Inflammation, fibrosis, and modulation of the process by mesenchymal stem/stromal cells.

1. Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury.

2. Density-Dependent Metabolic Heterogeneity in Human Mesenchymal Stem Cells.

3. Mitochondrial transfer between cells can rescue aerobic respiration.

4. Retention of nonhelical procollagen containing cis-hydroxyproline in rough endoplasmic reticulum.

5. Expansion of adipose mesenchymal stromal cells is affected by human platelet lysate and plating density.

Review 6. The resolution of inflammation: Principles and challenges.

7. Anti-inflammatory protein TSG-6 reduces inflammatory damage to the cornea following chemical and mechanical injury.

8. Phase-directed therapy: TSG-6 targeted to early inflammation improves bleomycin-injured lungs.

Review 9. TSG-6: a pluripotent inflammatory mediator?

10. Mesenchymal stem cells.

Review 1. Decorin is a devouring proteoglycan: Remodeling of intracellular catabolism via autophagy and mitophagy.

Review 2. Extracellular matrix: The driving force of mammalian diseases.

3. Mesenchymal Stromal Cells Inhibit Inflammatory Lymphangiogenesis in the Cornea by Suppressing Macrophage in a TSG-6-Dependent Manner.

Review 4. The origin of fibrogenic myofibroblasts in fibrotic liver.

Review 5. Mechanisms of liver fibrosis and its role in liver cancer.

6. TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury.

7. Metabolic reprogramming of murine cardiomyocytes during autophagy requires the extracellular nutrient sensor decorin.

8. Mesenchymal stem cells protect renal tubular cells via TSG-6 regulating macrophage function and phenotype switching.

9. Combined Bone Marrow Aspirate and Platelet-Rich Plasma for Cartilage Repair: Two-Year Clinical Results.

Review 10. Novel mechanisms and clinical trial endpoints in intestinal fibrosis.