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Literature DB >> 27859502

The origin of fibrogenic myofibroblasts in fibrotic liver.

Abstract

Liver fibrosis results from chronic liver injury of different etiologies. It is characterized by dysregulation of physiological remodeling, activation of myofibroblasts, and formation of a fibrous scar. Myofibroblasts develop contractile functions and secrete the extracellular matrix proteins that form this fibrous scar. Myofibroblasts are not present in the normal liver but activate and proliferate in response to injury and inflammation. This review summarizes the understanding and controversies on the contribution of cell populations to the myofibroblasts in liver fibrosis. (Hepatology 2017;65:1039-1043).

Entities: Chemical Disease Gene Species

Mesh：

Year: 2017 PMID： 27859502 PMCID： PMC5476301 DOI： 10.1002/hep.28948

Source DB: PubMed Journal: Hepatology ISSN： 0270-9139 Impact factor: 17.425

21 in total

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Authors: R Grant Rowe; Yongshun Lin; Ryoko Shimizu-Hirota; Shinichiro Hanada; Eric G Neilson; Joel K Greenson; Stephen J Weiss
Journal: Mol Cell Biol Date: 2011-04-11 Impact factor: 4.272

Review 2. Myofibroblasts.

Authors: Boris Hinz
Journal: Exp Eye Res Date: 2015-07-17 Impact factor: 3.467

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Authors: Kinji Asahina; Bin Zhou; William T Pu; Hidekazu Tsukamoto
Journal: Hepatology Date: 2011-02-03 Impact factor: 17.425

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Authors: David Cassiman; Louis Libbrecht; Valeer Desmet; Carl Denef; Tania Roskams
Journal: J Hepatol Date: 2002-02 Impact factor: 25.083

5. A dual reporter gene transgenic mouse demonstrates heterogeneity in hepatic fibrogenic cell populations.

Authors: Scott T Magness; Ramón Bataller; Liu Yang; David A Brenner
Journal: Hepatology Date: 2004-11 Impact factor: 17.425

6. Phenotypic change in portal fibroblasts in biliary fibrosis.

Authors: L Tang; Y Tanaka; F Marumo; C Sato
Journal: Liver Date: 1994-04

7. Myofibroblastic Conversion and Regeneration of Mesothelial Cells in Peritoneal and Liver Fibrosis.

Authors: Ingrid Lua; Yuchang Li; Lamioko S Pappoe; Kinji Asahina
Journal: Am J Pathol Date: 2015-12 Impact factor: 4.307

8. A novel murine model to deplete hepatic stellate cells uncovers their role in amplifying liver damage in mice.

Authors: Juan E Puche; Youngmin A Lee; Jingjing Jiao; Costica Aloman; Maria I Fiel; Ursula Muñoz; Thomas Kraus; Tingfang Lee; Hal F Yee; Scott L Friedman
Journal: Hepatology Date: 2013-01 Impact factor: 17.425

9. Characterization of hepatic stellate cells, portal fibroblasts, and mesothelial cells in normal and fibrotic livers.

Authors: Ingrid Lua; Yuchang Li; Jessica A Zagory; Kasper S Wang; Samuel W French; Jean Sévigny; Kinji Asahina
Journal: J Hepatol Date: 2016-01-19 Impact factor: 25.083

10. Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology.

Authors: Christine C Hsu; Juliane S Troeger; Ingmar Mederacke; Peter Huebener; Xueru Mu; Dianne H Dapito; Jean-Philippe Pradere; Robert F Schwabe
Journal: Nat Commun Date: 2013 Impact factor: 14.919

56 in total

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Authors: Fereshteh S Younesi; Dong Ok Son; Joao Firmino; Boris Hinz
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Review 2. Linking Race, Cancer Outcomes, and Tissue Repair.

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Journal: Am J Pathol Date: 2017-11-11 Impact factor: 4.307

3. Molecular Genetic and Immune Functional Responses Distinguish Bone Marrow Mesenchymal Stromal Cells from Hepatic Stellate Cells.

Authors: Raghavan Chinnadurai; Jenna Sands; Devi Rajan; Xiao Liu; Dalia Arafat; Rahul Das; Frank A Anania; Greg Gibson; Tatiana Kisseleva; Jacques Galipeau
Journal: Stem Cells Date: 2019-05-09 Impact factor: 6.277

4. Comparison of Carotenoids for Their Antifibrogenic Effects in Hepatic Stellate Cells.

Authors: Minkyung Bae; Mi-Bo Kim; Hyunju Kang; Young-Ki Park; Ji-Young Lee
Journal: Lipids Date: 2019-05-29 Impact factor: 1.880

5. Tyrosine kinase SYK is a potential therapeutic target for liver fibrosis.

Authors: Chen Qu; Dandan Zheng; Sai Li; Yingjun Liu; Anna Lidofsky; Jacinta A Holmes; Jianning Chen; Lu He; Lan Wei; Yadi Liao; Hui Yuan; Qimeng Jin; Zelong Lin; Qiaoting Hu; Yuchuan Jiang; Mengxian Tu; Xijun Chen; Weiming Li; Wenyu Lin; Bryan C Fuchs; Raymond T Chung; Jian Hong
Journal: Hepatology Date: 2018-05-21 Impact factor: 17.425

6. Praziquantel ameliorates CCl₄ -induced liver fibrosis in mice by inhibiting TGF-β/Smad signalling via up-regulating Smad7 in hepatic stellate cells.

Authors: Jinfeng Liu; Delong Kong; Jingfan Qiu; Yanci Xie; Zhongkui Lu; Chunlei Zhou; Xinjian Liu; Rong Zhang; Yong Wang
Journal: Br J Pharmacol Date: 2019-12-29 Impact factor: 8.739

7. Therapeutic effects of a small molecule agonist of the relaxin receptor ML290 in liver fibrosis.

Authors: Elena M Kaftanovskaya; Hooi Hooi Ng; Mariluz Soula; Bryan Rivas; Courtney Myhr; Brian A Ho; Briana A Cervantes; Thomas D Shupe; Mahesh Devarasetty; Xin Hu; Xin Xu; Samarjit Patnaik; Kenneth J Wilson; Elena Barnaeva; Marc Ferrer; Noel T Southall; Juan J Marugan; Colin E Bishop; Irina U Agoulnik; Alexander I Agoulnik
Journal: FASEB J Date: 2019-08-16 Impact factor: 5.191

8. Lipopolysaccharide induces the differentiation of hepatic progenitor cells into myofibroblasts via activation of the Hedgehog signaling pathway.

Authors: Xiao-Rong Pan; Ying-Ying Jing; Wen-Ting Liu; Zhi-Peng Han; Rong Li; Yang Yang; Jing-Ni Zhu; Xiao-Yong Li; Pei-Pei Li; Li-Xin Wei
Journal: Cell Cycle Date: 2017-05-31 Impact factor: 4.534

9. Hepatic Stellate Cell-Macrophage Crosstalk in Liver Fibrosis and Carcinogenesis.

Authors: Michitaka Matsuda; Ekihiro Seki
Journal: Semin Liver Dis Date: 2020-04-02 Impact factor: 6.115

10. Hydrogen selenide, a vital metabolite of sodium selenite, uncouples the sulfilimine bond and promotes the reversal of liver fibrosis.

Authors: Dongrui Luan; Zengteng Zhao; Dandan Xia; Qiuling Zheng; Xiaonan Gao; Kehua Xu; Bo Tang
Journal: Sci China Life Sci Date: 2020-09-01 Impact factor: 6.038