Literature DB >> 26798845

Challenges to Implementation of Global Translational Collaboration Platforms.

Yuri Quintana1.   

Abstract

Translational Collaboration Platforms connect clinical, genomics, and patient-reported data for the advancement of biomedical research, providing an opportunity to speed up the translating of basic science findings into clinical applications and new medicines. These platforms bring together data from both clinical and research databases and provide opportunities for multi-disciplinary research. Recent years have seen a significant growth of these platforms and some global collaborations research networks have been established using these platforms. In this brief summary of these platforms, we examine the challenges in implementation for global international research collaborations and challenges for the sustainability of research networks.

Entities:  

Keywords:  Big Data; Clinical Informatics; Collaboration; Genomics; Global Health; International Research; Translational Platforms

Year:  2015        PMID: 26798845      PMCID: PMC4717481          DOI: 10.15406/mojpb.2015.02.00065

Source DB:  PubMed          Journal:  MOJ Proteom Bioinform


  17 in total

1.  The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories.

Authors:  Griffin M Weber; Shawn N Murphy; Andrew J McMurry; Douglas Macfadden; Daniel J Nigrin; Susanne Churchill; Isaac S Kohane
Journal:  J Am Med Inform Assoc       Date:  2009-06-30       Impact factor: 4.497

2.  G-DOC: a systems medicine platform for personalized oncology.

Authors:  Subha Madhavan; Yuriy Gusev; Michael Harris; David M Tanenbaum; Robinder Gauba; Krithika Bhuvaneshwar; Andrew Shinohara; Kevin Rosso; Lavinia A Carabet; Lei Song; Rebecca B Riggins; Sivanesan Dakshanamurthy; Yue Wang; Stephen W Byers; Robert Clarke; Louis M Weiner
Journal:  Neoplasia       Date:  2011-09       Impact factor: 5.715

3.  caGrid: design and implementation of the core architecture of the cancer biomedical informatics grid.

Authors:  Joel Saltz; Scott Oster; Shannon Hastings; Stephen Langella; Tahsin Kurc; William Sanchez; Manav Kher; Arumani Manisundaram; Krishnakant Shanbhag; Peter Covitz
Journal:  Bioinformatics       Date:  2006-06-09       Impact factor: 6.937

4.  On experiences of i2b2 (Informatics for integrating biology and the bedside) database with Japanese clinical patients' data.

Authors:  Takako Takai-Igarashi; Ryo Akasaka; Kenji Suzuki; Takahisa Furukawa; Makiko Yoshida; Keisuke Inoue; Tomohisa Maruyama; Toshimasa Maejima; Masahiro Bando; Masakazu Takasaki; Miki Sakota; Maki Eguchi; Akihiko Konagaya; Hiroya Matsuura; Toyotaro Suzumura; Hiroshi Tanaka
Journal:  Bioinformation       Date:  2011-03-26

5.  POND4Kids: a global web-based database for pediatric hematology and oncology outcome evaluation and collaboration.

Authors:  Yuri Quintana; Aman N Patel; Magada Arreola; Federico G Antillon; Raul C Ribeiro; Scott C Howard
Journal:  Stud Health Technol Inform       Date:  2013

Review 6.  Next-generation sequencing in the clinic: are we ready?

Authors:  Leslie G Biesecker; Wylie Burke; Isaac Kohane; Sharon E Plon; Ron Zimmern
Journal:  Nat Rev Genet       Date:  2012-11       Impact factor: 53.242

7.  The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data.

Authors:  Ethan Cerami; Jianjiong Gao; Ugur Dogrusoz; Benjamin E Gross; Selcuk Onur Sumer; Bülent Arman Aksoy; Anders Jacobsen; Caitlin J Byrne; Michael L Heuer; Erik Larsson; Yevgeniy Antipin; Boris Reva; Arthur P Goldberg; Chris Sander; Nikolaus Schultz
Journal:  Cancer Discov       Date:  2012-05       Impact factor: 39.397

8.  Effective knowledge management in translational medicine.

Authors:  Sándor Szalma; Venkata Koka; Tatiana Khasanova; Eric D Perakslis
Journal:  J Transl Med       Date:  2010-07-19       Impact factor: 5.531

Review 9.  Translational research platforms integrating clinical and omics data: a review of publicly available solutions.

Authors:  Vincent Canuel; Bastien Rance; Paul Avillach; Patrice Degoulet; Anita Burgun
Journal:  Brief Bioinform       Date:  2014-03-07       Impact factor: 11.622

10.  tranSMART: An Open Source and Community-Driven Informatics and Data Sharing Platform for Clinical and Translational Research.

Authors:  Brian D Athey; Michael Braxenthaler; Magali Haas; Yike Guo
Journal:  AMIA Jt Summits Transl Sci Proc       Date:  2013-03-18
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  1 in total

1.  Development, Evaluation, and Implementation of a Pan-African Cancer Research Network: Men of African Descent and Carcinoma of the Prostate.

Authors:  Caroline Andrews; Brian Fortier; Amy Hayward; Ruth Lederman; Lindsay Petersen; Jo McBride; Desiree C Petersen; Olabode Ajayi; Paidamoyo Kachambwa; Moleboheng Seutloali; Aubrey Shoko; Mamokhosana Mokhosi; Reinhard Hiller; Marcia Adams; Chrissie Ongaco; Elizabeth Pugh; Jane Romm; Tameka Shelford; Frank Chinegwundoh; Ben Adusei; Sunny Mante; Nana Yaa Snyper; Ilir Agalliu; David W Lounsbury; Thomas Rohan; Alex Orfanos; Yuri Quintana; Judith S Jacobson; Alfred I Neugut; Edward Gelmann; Joseph Lachance; Cherif Dial; Thierno Amadou Diallo; Mohamed Jalloh; Serigne Magueye Gueye; Papa Moussa Sène Kane; Halimatou Diop; Anna Julienne Ndiaye; Amina Sow Sall; Ndeye Coumba Toure-Kane; Ezenwa Onyemata; Alash'le Abimiku; Andrew A Adjei; Richard Biritwum; Richard Gyasi; Mathew Kyei; James E Mensah; Julian Okine; Vicky Okyne; Isabella Rockson; Evelyn Tay; Yao Tettey; Edward Yeboah; Wenlong C Chen; Elvira Singh; Michael B Cook; Christine N Duffy; Ann Hsing; Cassandra Claire Soo; Pedro Fernandez; Hayley Irusen; Oseremen Aisuodionoe-Shadrach; Abubakar Mustapha Jamda; Peter Oluwole Olabode; Maxwell Madueke Nwegbu; Olalekan Hafees Ajibola; Olushola Jeremiah Ajamu; Yakubu Garba Ambuwa; Akindele Olupelumi Adebiyi; Michael Asuzu; Olufemi Ogunbiyi; Olufemi Popoola; Olayiwola Shittu; Olukemi Amodu; Emeka Odiaka; Ifeoluwa Makinde; Maureen Joffe; Audrey Pentz; Timothy R Rebbeck
Journal:  J Glob Oncol       Date:  2018-09
  1 in total

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