Literature DB >> 26798751

Expanding Horizons for Abdominal Aortic Aneurysms.

Rachel C Rolph1, Matthew Waltham1, Alberto Smith1, Helena Kuivaniemi2.   

Abstract

Recent technological advances have allowed researchers to interrogate the genetic basis of abdominal aortic aneurysms in great detail. The results from these studies are expected to transform our understanding of this complex disease with both multiple genetic and environmental risk factors. Clinicians need to keep abreast of these genetic findings and understand the implications for their practice. Patients will become increasingly informed on genetic risk, and a new era of individualized risk assessment for AAA is just beginning. This brief update aims to provide the clinician with a succinct précis of the recent progress in this area.

Entities:  

Keywords:  Aneurysm; Association Studies; DNA Sequencing; Genetic; Risk score

Year:  2015        PMID: 26798751      PMCID: PMC4714933          DOI: 10.12945/j.aorta.2015.14-041

Source DB:  PubMed          Journal:  Aorta (Stamford)        ISSN: 2325-4637


  43 in total

Review 1.  The regulation of INK4/ARF in cancer and aging.

Authors:  William Y Kim; Norman E Sharpless
Journal:  Cell       Date:  2006-10-20       Impact factor: 41.582

2.  Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene.

Authors:  Y Kotake; T Nakagawa; K Kitagawa; S Suzuki; N Liu; M Kitagawa; Y Xiong
Journal:  Oncogene       Date:  2010-12-13       Impact factor: 9.867

3.  The genetics of abdominal aortic aneurysms: a comprehensive meta-analysis involving eight candidate genes in over 16,700 patients.

Authors:  Peter McColgan; George E Peck; Roger M Greenhalgh; Pankaj Sharma
Journal:  Int Surg       Date:  2009 Oct-Dec

4.  Polymorphisms of genes involved in extracellular matrix remodeling and abdominal aortic aneurysm.

Authors:  Claudia Saracini; Paola Bolli; Elena Sticchi; Giovanni Pratesi; Raffaele Pulli; Francesco Sofi; Carlo Pratesi; Gian Franco Gensini; Rosanna Abbate; Betti Giusti
Journal:  J Vasc Surg       Date:  2011-11-16       Impact factor: 4.268

Review 5.  Genetic profiling and individualized assessment of fracture risk.

Authors:  Tuan V Nguyen; John A Eisman
Journal:  Nat Rev Endocrinol       Date:  2013-02-05       Impact factor: 43.330

6.  Resequencing and clinical associations of the 9p21.3 region: a comprehensive investigation in the Framingham heart study.

Authors:  Andrew D Johnson; Shih-Jen Hwang; Arend Voorman; Alanna Morrison; Gina M Peloso; Yi-Hsiang Hsu; George Thanassoulis; Christopher Newton-Cheh; Ian S Rogers; Udo Hoffmann; Jane E Freedman; Caroline S Fox; Bruce M Psaty; Eric Boerwinkle; L Adrienne Cupples; Christopher J O'Donnell
Journal:  Circulation       Date:  2013-01-11       Impact factor: 29.690

Review 7.  Genetics of abdominal aortic aneurysm.

Authors:  Jonathan Golledge; Helena Kuivaniemi
Journal:  Curr Opin Cardiol       Date:  2013-05       Impact factor: 2.161

8.  Family members of patients with abdominal aortic aneurysms are at increased risk for aneurysms: analysis of 618 probands and their families from the Liège AAA Family Study.

Authors:  Natzi Sakalihasan; Jean-Olivier Defraigne; Marie-Ange Kerstenne; Jean-Paul Cheramy-Bien; Diane T Smelser; Gerard Tromp; Helena Kuivaniemi
Journal:  Ann Vasc Surg       Date:  2013-12-21       Impact factor: 1.466

9.  A variant in LDLR is associated with abdominal aortic aneurysm.

Authors:  Declan T Bradley; Anne E Hughes; Stephen A Badger; Gregory T Jones; Seamus C Harrison; Benjamin J Wright; Suzannah Bumpstead; Annette F Baas; Sólveig Grétarsdóttir; Kevin Burnand; Anne H Child; Rachel E Clough; Gillian Cockerill; Hany Hafez; D Julian A Scott; Robert A S Ariëns; Anne Johnson; Soroush Sohrabi; Alberto Smith; Matthew M Thompson; Frank M van Bockxmeer; Matthew Waltham; Stefán E Matthíasson; Gudmar Thorleifsson; Unnur Thorsteinsdottir; Jan D Blankensteijn; Joep A W Teijink; Cisca Wijmenga; Jacqueline de Graaf; Lambertus A Kiemeney; John B Wild; Sarah Edkins; Rhian Gwilliam; Sarah E Hunt; Simon Potter; Jes S Lindholt; Jonathan Golledge; Paul E Norman; Andre van Rij; Janet T Powell; Per Eriksson; Kári Stefánsson; John R Thompson; Steve E Humphries; Robert D Sayers; Panos Deloukas; Nilesh J Samani; Matthew J Bown
Journal:  Circ Cardiovasc Genet       Date:  2013-09-17

Review 10.  Exome sequencing and complex disease: practical aspects of rare variant association studies.

Authors:  Ron Do; Sekar Kathiresan; Gonçalo R Abecasis
Journal:  Hum Mol Genet       Date:  2012-09-13       Impact factor: 6.150

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  1 in total

Review 1.  Abdominal Aortic Aneurysm: Evolving Controversies and Uncertainties.

Authors:  Davide Carino; Timur P Sarac; Bulat A Ziganshin; John A Elefteriades
Journal:  Int J Angiol       Date:  2018-05-29
  1 in total

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