Literature DB >> 26798326

R package PRIMsrc: Bump Hunting by Patient Rule Induction Method for Survival, Regression and Classification.

Jean-Eudes Dazard1, Michael Choe1, Michael LeBlanc2, J Sunil Rao3.   

Abstract

PRIMsrc is a novel implementation of a non-parametric bump hunting procedure, based on the Patient Rule Induction Method (PRIM), offering a unified treatment of outcome variables, including censored time-to-event (Survival), continuous (Regression) and discrete (Classification) responses. To fit the model, it uses a recursive peeling procedure with specific peeling criteria and stopping rules depending on the response. To validate the model, it provides an objective function based on prediction-error or other specific statistic, as well as two alternative cross-validation techniques, adapted to the task of decision-rule making and estimation in the three types of settings. PRIMsrc comes as an open source R package, including at this point: (i) a main function for fitting a Survival Bump Hunting model with various options allowing cross-validated model selection to control model size (#covariates) and model complexity (#peeling steps) and generation of cross-validated end-point estimates; (ii) parallel computing; (iii) various S3-generic and specific plotting functions for data visualization, diagnostic, prediction, summary and display of results. It is available on CRAN and GitHub.

Entities:  

Keywords:  Bump Hunting; Cross-Validation; Non-Parametric Methods; Parallel Programming; R Package; Rule-Induction Methods

Year:  2015        PMID: 26798326      PMCID: PMC4718587     

Source DB:  PubMed          Journal:  Proc Am Stat Assoc        ISSN: 1543-3218


  16 in total

1.  Partitioning and peeling for constructing prognostic groups.

Authors:  Michael LeBlanc; Joth Jacobson; John Crowley
Journal:  Stat Methods Med Res       Date:  2002-06       Impact factor: 3.021

2.  Prediction error estimation: a comparison of resampling methods.

Authors:  Annette M Molinaro; Richard Simon; Ruth M Pfeiffer
Journal:  Bioinformatics       Date:  2005-05-19       Impact factor: 6.937

3.  Adaptive risk group refinement.

Authors:  Michael LeBlanc; James Moon; John Crowley
Journal:  Biometrics       Date:  2005-06       Impact factor: 2.571

4.  Sample size planning for developing classifiers using high-dimensional DNA microarray data.

Authors:  Kevin K Dobbin; Richard M Simon
Journal:  Biostatistics       Date:  2006-04-13       Impact factor: 5.899

5.  Using cross-validation to evaluate predictive accuracy of survival risk classifiers based on high-dimensional data.

Authors:  Richard M Simon; Jyothi Subramanian; Ming-Chung Li; Supriya Menezes
Journal:  Brief Bioinform       Date:  2011-02-15       Impact factor: 11.622

6.  Local Sparse Bump Hunting.

Authors:  Jean-Eudes Dazard; J Sunil Rao
Journal:  J Comput Graph Stat       Date:  2010-12       Impact factor: 2.302

7.  Evaluating the yield of medical tests.

Authors:  F E Harrell; R M Califf; D B Pryor; K L Lee; R A Rosati
Journal:  JAMA       Date:  1982-05-14       Impact factor: 56.272

8.  Cross-Validation of Survival Bump Hunting by Recursive Peeling Methods.

Authors:  Jean-Eudes Dazard; Michael Choe; Michael LeBlanc; J Sunil Rao
Journal:  Proc Am Stat Assoc       Date:  2014-08

9.  Bias in error estimation when using cross-validation for model selection.

Authors:  Sudhir Varma; Richard Simon
Journal:  BMC Bioinformatics       Date:  2006-02-23       Impact factor: 3.169

10.  Markers for early detection of cancer: statistical guidelines for nested case-control studies.

Authors:  Stuart G Baker; Barnett S Kramer; Sudhir Srivastava
Journal:  BMC Med Res Methodol       Date:  2002-02-28       Impact factor: 4.615

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  2 in total

1.  Cross-validation and Peeling Strategies for Survival Bump Hunting using Recursive Peeling Methods.

Authors:  Jean-Eudes Dazard; Michael Choe; Michael LeBlanc; J Sunil Rao
Journal:  Stat Anal Data Min       Date:  2016-01-22       Impact factor: 1.051

2.  A risk score staging system based on the expression of seven genes predicts the outcome of bladder cancer.

Authors:  Jianfeng Chu; Ning Li; Fengguang Li
Journal:  Oncol Lett       Date:  2018-06-05       Impact factor: 2.967

  2 in total

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