Literature DB >> 26798060

Concise Review: Organoids Are a Powerful Tool for the Study of Liver Disease and Personalized Treatment Design in Humans and Animals.

Sathidpak Nantasanti1, Alain de Bruin2, Jan Rothuizen3, Louis C Penning3, Baukje A Schotanus4.   

Abstract

Organoids are three-dimensional culture systems in which adult stem cells and their progeny grow and represent the native physiology of the cells in vivo. Organoids have been successfully derived from several organ systems in both animal models and human patients. Organoids have been used for fundamental research, disease modeling, drug testing, and transplantation. In this review, we summarize the applications of liver-derived organoids and discuss their potential. It is likely that organoids will provide an invaluable tool to unravel disease mechanisms, design novel (personalized) treatment strategies, and generate autologous stem cells for gene editing and transplantation purposes. ©AlphaMed Press.

Entities:  

Keywords:  Adult stem cell culture; Applications; Liver; Organoids

Mesh：

Year:  2016        PMID： 26798060      PMCID： PMC4807664          DOI： 10.5966/sctm.2015-0152

Source DB:  PubMed          Journal:  Stem Cells Transl Med        ISSN： 2157-6564            Impact factor:   6.940


  48 in total

Review 1.  Advances in experimental systems to study hepatitis C virus in vitro and in vivo.

Authors:  Maria Teresa Catanese; Marcus Dorner
Journal:  Virology       Date:  2015-04-04       Impact factor: 3.616

2.  Complete replication of hepatitis B virus and hepatitis C virus in a newly developed hepatoma cell line.

Authors:  Darong Yang; Chaohui Zuo; Xiaohong Wang; Xianghe Meng; Binbin Xue; Nianli Liu; Rong Yu; Yuwen Qin; Yimin Gao; Qiuping Wang; Jun Hu; Ling Wang; Zebin Zhou; Bing Liu; Deming Tan; Yang Guan; Haizhen Zhu
Journal:  Proc Natl Acad Sci U S A       Date:  2014-03-10       Impact factor: 11.205

3.  Hepatitis C virus inhibits intracellular interferon alpha expression in human hepatic cell lines.

Authors:  Ting Zhang; Rong-Tuan Lin; Yuan Li; Steven D Douglas; Catherine Maxcey; Chun Ho; Jian-Ping Lai; Yan-Jian Wang; Qi Wan; Wen-Zhe Ho
Journal:  Hepatology       Date:  2005-10       Impact factor: 17.425

Review 4.  Hepatitis C virus entry into hepatocytes: molecular mechanisms and targets for antiviral therapies.

Authors:  Mirjam B Zeisel; Isabel Fofana; Samira Fafi-Kremer; Thomas F Baumert
Journal:  J Hepatol       Date:  2010-11-11       Impact factor: 25.083

Review 5.  Translational approaches: from fatty liver to non-alcoholic steatohepatitis.

Authors:  Natalia Rosso; Norberto C Chavez-Tapia; Claudio Tiribelli; Stefano Bellentani
Journal:  World J Gastroenterol       Date:  2014-07-21       Impact factor: 5.742

6.  Quantitation of transplanted hepatic mass necessary to cure the Gunn rat model of hyperbilirubinemia.

Authors:  K Asonuma; J C Gilbert; J E Stein; T Takeda; J P Vacanti
Journal:  J Pediatr Surg       Date:  1992-03       Impact factor: 2.545

7.  Prospective derivation of a living organoid biobank of colorectal cancer patients.

Authors:  Marc van de Wetering; Hayley E Francies; Joshua M Francis; Gergana Bounova; Francesco Iorio; Apollo Pronk; Winan van Houdt; Joost van Gorp; Amaro Taylor-Weiner; Lennart Kester; Anne McLaren-Douglas; Joyce Blokker; Sridevi Jaksani; Sina Bartfeld; Richard Volckman; Peter van Sluis; Vivian S W Li; Sara Seepo; Chandra Sekhar Pedamallu; Kristian Cibulskis; Scott L Carter; Aaron McKenna; Michael S Lawrence; Lee Lichtenstein; Chip Stewart; Jan Koster; Rogier Versteeg; Alexander van Oudenaarden; Julio Saez-Rodriguez; Robert G J Vries; Gad Getz; Lodewyk Wessels; Michael R Stratton; Ultan McDermott; Matthew Meyerson; Mathew J Garnett; Hans Clevers
Journal:  Cell       Date:  2015-05-07       Impact factor: 41.582

8.  Long-term culture of genome-stable bipotent stem cells from adult human liver.

Authors:  Meritxell Huch; Helmuth Gehart; Ruben van Boxtel; Karien Hamer; Francis Blokzijl; Monique M A Verstegen; Ewa Ellis; Martien van Wenum; Sabine A Fuchs; Joep de Ligt; Marc van de Wetering; Nobuo Sasaki; Susanne J Boers; Hans Kemperman; Jeroen de Jonge; Jan N M Ijzermans; Edward E S Nieuwenhuis; Ruurdtje Hoekstra; Stephen Strom; Robert R G Vries; Luc J W van der Laan; Edwin Cuppen; Hans Clevers
Journal:  Cell       Date:  2014-12-18       Impact factor: 41.582

9.  Hepatic progenitor cells of biliary origin with liver repopulation capacity.

Authors:  Wei-Yu Lu; Thomas G Bird; Luke Boulter; Atsunori Tsuchiya; Alicia M Cole; Trevor Hay; Rachel V Guest; Davina Wojtacha; Tak Yung Man; Alison Mackinnon; Rachel A Ridgway; Timothy Kendall; Michael J Williams; Thomas Jamieson; Alex Raven; David C Hay; John P Iredale; Alan R Clarke; Owen J Sansom; Stuart J Forbes
Journal:  Nat Cell Biol       Date:  2015-07-20       Impact factor: 28.824

Review 10.  In vitro differentiation of embryonic and adult stem cells into hepatocytes: state of the art.

Authors:  Sarah Snykers; Joery De Kock; Vera Rogiers; Tamara Vanhaecke
Journal:  Stem Cells       Date:  2009-03       Impact factor: 6.277
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  24 in total

Review 1.  Investigation of human trophoblast invasion in vitro.

Authors:  Yassen Abbas; Margherita Y Turco; Graham J Burton; Ashley Moffett
Journal:  Hum Reprod Update       Date:  2020-06-18       Impact factor: 15.610

2.  A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age-dependent differences in absorption.

Authors:  Eva J Streekstra; Márton Kiss; Jeroen van den Heuvel; Johan Nicolaï; Petra van den Broek; Sanne M B I Botden; Martijn W J Stommel; Lara van Rijssel; Anna-Lena Ungell; Evita van de Steeg; Frans G M Russel; Saskia N de Wildt
Journal:  Clin Transl Sci       Date:  2022-08-12       Impact factor: 4.438

3.  Human cardiac organoids for the modelling of myocardial infarction and drug cardiotoxicity.

Authors:  Dylan J Richards; Yang Li; Charles M Kerr; Jenny Yao; Gyda C Beeson; Robert C Coyle; Xun Chen; Jia Jia; Brooke Damon; Robert Wilson; E Starr Hazard; Gary Hardiman; Donald R Menick; Craig C Beeson; Hai Yao; Tong Ye; Ying Mei
Journal:  Nat Biomed Eng       Date:  2020-04-13       Impact factor: 25.671

Review 4.  Concise Review: Current Status of Three-Dimensional Organoids as Preclinical Models.

Authors:  Garima Kaushik; Moorthy P Ponnusamy; Surinder K Batra
Journal:  Stem Cells       Date:  2018-07-29       Impact factor: 6.277

Review 5.  Stem cells and genome editing: approaches to tissue regeneration and regenerative medicine.

Authors:  Nozomu Takata; Mototsugu Eiraku
Journal:  J Hum Genet       Date:  2017-10-11       Impact factor: 3.172

Review 6.  Disease Modeling Using 3D Organoids Derived from Human Induced Pluripotent Stem Cells.

Authors:  Beatrice Xuan Ho; Nicole Min Qian Pek; Boon-Seng Soh
Journal:  Int J Mol Sci       Date:  2018-03-21       Impact factor: 5.923

7.  Development of a cell-based assay to identify hepatitis B virus entry inhibitors targeting the sodium taurocholate cotransporting polypeptide.

Authors:  Kei Miyakawa; Satoko Matsunaga; Yutaro Yamaoka; Mina Dairaku; Kento Fukano; Hirokazu Kimura; Tomoyuki Chimuro; Hironori Nishitsuji; Koichi Watashi; Kunitada Shimotohno; Takaji Wakita; Akihide Ryo
Journal:  Oncotarget       Date:  2018-05-04

8.  Liquid Marble as Bioreactor for Engineering Three-Dimensional Toroid Tissues.

Authors:  Raja K Vadivelu; Harshad Kamble; Ahmed Munaz; Nam-Trung Nguyen
Journal:  Sci Rep       Date:  2017-09-28       Impact factor: 4.379

Review 9.  Clinical application of stem cell in patients with end-stage liver disease: progress and challenges.

Authors:  Ya-Chao Tao; En-Qiang Chen
Journal:  Ann Transl Med       Date:  2020-04

10.  Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma.

Authors:  Tanvir Hossain; Shahla Romal; Elisa De Crignis; Fabrizia Carofiglio; Panagiotis Moulos; Mir Mubashir Khalid; Shringar Rao; Ameneh Bazrafshan; Monique Ma Verstegen; Farzin Pourfarzad; Christina Koutsothanassis; Helmuth Gehart; Tsung Wai Kan; Robert-Jan Palstra; Charles Boucher; Jan Nm IJzermans; Meritxell Huch; Sylvia F Boj; Robert Vries; Hans Clevers; Luc Jw van der Laan; Pantelis Hatzis; Tokameh Mahmoudi
Journal:  Elife       Date:  2021-07-30       Impact factor: 8.140
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