Literature DB >> 26794394

Pancreatic cancer: Current research and future directions.

Marco Falasca1, Minkyoung Kim2, Ilaria Casari2.   

Abstract

Despite the survival rate advancements in different types of cancer in the last 40 years, the perspective for pancreatic cancer patients has seen no substantial changes. Indeed, the five year survival rate remains around 5%. Nevertheless, in the last decade we have witnessed an increased interest in pancreatic cancer biology and this has produced a substantial increment in our knowledge on pancreatic cancer progression. The big challenge is now to translate this knowledge in better outcomes for patients. The aim of this review is to describe the latest discoveries and advancements in pancreatic cancer research and to discuss future directions.
Copyright © 2016 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Cancer metabolism; Exosomes; MicroRNA; Pancreatic cancer; Tumour stroma

Mesh：

Substances：

Year:  2016        PMID： 26794394     DOI： 10.1016/j.bbcan.2016.01.001

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  34 in total

1.  High toll-like receptor (TLR) 9 expression is associated with better prognosis in surgically treated pancreatic cancer patients.

Authors:  Joni Leppänen; Olli Helminen; Heikki Huhta; Joonas H Kauppila; Joel Isohookana; Kirsi-Maria Haapasaari; Petri Lehenkari; Juha Saarnio; Tuomo J Karttunen
Journal:  Virchows Arch       Date:  2017-02-12       Impact factor: 4.064

2.  GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine.

Authors:  R Ferro; A Adamska; R Lattanzio; I Mavrommati; C E Edling; S A Arifin; C A Fyffe; G Sala; L Sacchetto; G Chiorino; V De Laurenzi; M Piantelli; O J Sansom; T Maffucci; M Falasca
Journal:  Oncogene       Date:  2018-07-30       Impact factor: 9.867

Review 3.  Targeting reactive oxygen species in development and progression of pancreatic cancer.

Authors:  Nisha Durand; Peter Storz
Journal:  Expert Rev Anticancer Ther       Date:  2016-11-23       Impact factor: 4.512

Review 4.  Pancreatic cancer subtypes: a roadmap for precision medicine.

Authors:  Carolina Torres; Paul J Grippo
Journal:  Ann Med       Date:  2018-03-22       Impact factor: 4.709

Review 5.  Overcoming chemoresistance by targeting reprogrammed metabolism: the Achilles' heel of pancreatic ductal adenocarcinoma.

Authors:  Abudureyimu Tuerhong; Jin Xu; Si Shi; Zhen Tan; Qingcai Meng; Jie Hua; Jiang Liu; Bo Zhang; Wei Wang; Xianjun Yu; Chen Liang
Journal:  Cell Mol Life Sci       Date:  2021-06-15       Impact factor: 9.261

Review 6.  Oncologic Photodynamic Therapy: Basic Principles, Current Clinical Status and Future Directions.

Authors:  Demian van Straten; Vida Mashayekhi; Henriette S de Bruijn; Sabrina Oliveira; Dominic J Robinson
Journal:  Cancers (Basel)       Date:  2017-02-18       Impact factor: 6.639

7.  Study on the expression profile and role of decorin in the progression of pancreatic cancer.

Authors:  Litao Zhang; Chao Liu; Huijie Gao; Caiju Zhou; Wei Qin; Jian Wang; Lingxin Meng; Huiyun Wang; Qiang Ren; Yuntao Zhang
Journal:  Aging (Albany NY)       Date:  2021-05-21       Impact factor: 5.682

8.  Profile of MMP and TIMP Expression in Human Pancreatic Stellate Cells: Regulation by IL-1α and TGFβ and Implications for Migration of Pancreatic Cancer Cells.

Authors:  Vegard Tjomsland; Eva Pomianowska; Monica Aasrum; Dagny Sandnes; Caroline Sophie Verbeke; Ivar Prydz Gladhaug
Journal:  Neoplasia       Date:  2016-07       Impact factor: 5.715

Review 9.  Application of glycoscience to the early detection of pancreatic cancer.

Authors:  Eiji Miyoshi; Yoshihiro Kamada
Journal:  Cancer Sci       Date:  2016-09-02       Impact factor: 6.716

10.  A recombinantly tailored β-defensin that displays intensive macropinocytosis-mediated uptake exerting potent efficacy against K-Ras mutant pancreatic cancer.

Authors:  Yue Du; Bo-Yang Shang; Wei-Jin Sheng; Sheng-Hua Zhang; Yi Li; Qing-Fang Miao; Yong-Su Zhen
Journal:  Oncotarget       Date:  2016-09-06
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