Literature DB >> 26789776

Tissue-Specific and Genetic Regulation of Insulin Sensitivity-Associated Transcripts in African Americans.

Neeraj K Sharma1, Satria P Sajuthi1, Jeff W Chou1, Jorge Calles-Escandon1, Jamehl Demons1, Samantha Rogers1, Lijun Ma1, Nicholette D Palmer1, David R McWilliams1, John Beal1, Mary E Comeau1, Kristina Cherry1, Gregory A Hawkins1, Lata Menon1, Ethel Kouba1, Donna Davis1, Marcie Burris1, Sara J Byerly1, Linda Easter1, Donald W Bowden1, Barry I Freedman1, Carl D Langefeld1, Swapan K Das1.   

Abstract

Integrative multiomics analyses of adipose and muscle tissue transcripts, S, and genotypes revealed novel genetic regulatory mechanisms of insulin resistance in African Americans.

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Year:  2016        PMID： 26789776      PMCID： PMC4880154          DOI： 10.1210/jc.2015-3336

Source DB:  PubMed          Journal:  J Clin Endocrinol Metab        ISSN： 0021-972X            Impact factor:   5.958


  61 in total

1.  Mitochondrial dysfunction in white adipose tissue.

Authors:  Christine M Kusminski; Philipp E Scherer
Journal:  Trends Endocrinol Metab       Date:  2012-07-10       Impact factor: 12.015

2.  Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance.

Authors:  Timothy R Koves; John R Ussher; Robert C Noland; Dorothy Slentz; Merrie Mosedale; Olga Ilkayeva; James Bain; Robert Stevens; Jason R B Dyck; Christopher B Newgard; Gary D Lopaschuk; Deborah M Muoio
Journal:  Cell Metab       Date:  2008-01       Impact factor: 27.287

3.  Profiling gene transcription in vivo reveals adipose tissue as an immediate target of tumor necrosis factor-alpha: implications for insulin resistance.

Authors:  Hong Ruan; Philip D G Miles; Christine M Ladd; Kenneth Ross; Todd R Golub; Jerrold M Olefsky; Harvey F Lodish
Journal:  Diabetes       Date:  2002-11       Impact factor: 9.461

Review 4.  Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future.

Authors:  Steven E Kahn; Mark E Cooper; Stefano Del Prato
Journal:  Lancet       Date:  2013-12-03       Impact factor: 79.321

Review 5.  Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes.

Authors:  Adilson Guilherme; Joseph V Virbasius; Vishwajeet Puri; Michael P Czech
Journal:  Nat Rev Mol Cell Biol       Date:  2008-05       Impact factor: 94.444

6.  Inverse regulation of inflammation and mitochondrial function in adipose tissue defines extreme insulin sensitivity in morbidly obese patients.

Authors:  Mohammed Qatanani; Yejun Tan; Radu Dobrin; Danielle M Greenawalt; Guanghui Hu; Wenqing Zhao; Jerrold M Olefsky; Dorothy D Sears; Lee M Kaplan; Daniel M Kemp
Journal:  Diabetes       Date:  2012-12-06       Impact factor: 9.461

7.  P-selectin glycoprotein ligand-1 deficiency is protective against obesity-related insulin resistance.

Authors:  Chikage Sato; Kenichi Shikata; Daisho Hirota; Motofumi Sasaki; Shingo Nishishita; Satoshi Miyamoto; Ryo Kodera; Daisuke Ogawa; Atsuhito Tone; Hitomi Usui Kataoka; Jun Wada; Nobuo Kajitani; Hirofumi Makino
Journal:  Diabetes       Date:  2010-10-22       Impact factor: 9.461

8.  Adipose co-expression networks across Finns and Mexicans identify novel triglyceride-associated genes.

Authors:  Blake E Haas; Steve Horvath; Kirsi H Pietiläinen; Rita M Cantor; Elina Nikkola; Daphna Weissglas-Volkov; Aila Rissanen; Mete Civelek; Ivette Cruz-Bautista; Laura Riba; Johanna Kuusisto; Jaakko Kaprio; Teresa Tusie-Luna; Markku Laakso; Carlos A Aguilar-Salinas; Päivi Pajukanta
Journal:  BMC Med Genomics       Date:  2012-12-06       Impact factor: 3.063

9.  Mapping cis- and trans-regulatory effects across multiple tissues in twins.

Authors:  Elin Grundberg; Kerrin S Small; Åsa K Hedman; Alexandra C Nica; Alfonso Buil; Sarah Keildson; Jordana T Bell; Tsun-Po Yang; Eshwar Meduri; Amy Barrett; James Nisbett; Magdalena Sekowska; Alicja Wilk; So-Youn Shin; Daniel Glass; Mary Travers; Josine L Min; Sue Ring; Karen Ho; Gudmar Thorleifsson; Augustine Kong; Unnur Thorsteindottir; Chrysanthi Ainali; Antigone S Dimas; Neelam Hassanali; Catherine Ingle; David Knowles; Maria Krestyaninova; Christopher E Lowe; Paola Di Meglio; Stephen B Montgomery; Leopold Parts; Simon Potter; Gabriela Surdulescu; Loukia Tsaprouni; Sophia Tsoka; Veronique Bataille; Richard Durbin; Frank O Nestle; Stephen O'Rahilly; Nicole Soranzo; Cecilia M Lindgren; Krina T Zondervan; Kourosh R Ahmadi; Eric E Schadt; Kari Stefansson; George Davey Smith; Mark I McCarthy; Panos Deloukas; Emmanouil T Dermitzakis; Tim D Spector
Journal:  Nat Genet       Date:  2012-09-02       Impact factor: 38.330

10.  Expression of phosphofructokinase in skeletal muscle is influenced by genetic variation and associated with insulin sensitivity.

Authors:  Sarah Keildson; Joao Fadista; Claes Ladenvall; Åsa K Hedman; Targ Elgzyri; Kerrin S Small; Elin Grundberg; Alexandra C Nica; Daniel Glass; J Brent Richards; Amy Barrett; James Nisbet; Hou-Feng Zheng; Tina Rönn; Kristoffer Ström; Karl-Fredrik Eriksson; Inga Prokopenko; Timothy D Spector; Emmanouil T Dermitzakis; Panos Deloukas; Mark I McCarthy; Johan Rung; Leif Groop; Paul W Franks; Cecilia M Lindgren; Ola Hansson
Journal:  Diabetes       Date:  2013-12-04       Impact factor: 9.461
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  13 in total

1.  Adipose Tissue Transferrin and Insulin Resistance.

Authors:  Donald A McClain; Neeraj K Sharma; Shalini Jain; Alexandria Harrison; Lipika N Salaye; Mary E Comeau; Carl D Langefeld; Felipe R Lorenzo; Swapan K Das
Journal:  J Clin Endocrinol Metab       Date:  2018-11-01       Impact factor: 5.958

2.  Genetic regulation of adipose tissue transcript expression is involved in modulating serum triglyceride and HDL-cholesterol.

Authors:  Satria P Sajuthi; Neeraj K Sharma; Mary E Comeau; Jeff W Chou; Donald W Bowden; Barry I Freedman; Carl D Langefeld; John S Parks; Swapan K Das
Journal:  Gene       Date:  2017-08-26       Impact factor: 3.688

3.  Transcriptome-wide analyses of adipose tissue in outbred rats reveal genetic regulatory mechanisms relevant for human obesity.

Authors:  Wesley L Crouse; Swapan K Das; Thu Le; Gregory Keele; Katie Holl; Osborne Seshie; Ann L Craddock; Neeraj K Sharma; Mary E Comeau; Carl D Langefeld; Gregory A Hawkins; Richard Mott; William Valdar; Leah C Solberg Woods
Journal:  Physiol Genomics       Date:  2022-04-25       Impact factor: 4.297

4.  Mapping adipose and muscle tissue expression quantitative trait loci in African Americans to identify genes for type 2 diabetes and obesity.

Authors:  Satria P Sajuthi; Neeraj K Sharma; Jeff W Chou; Nicholette D Palmer; David R McWilliams; John Beal; Mary E Comeau; Lijun Ma; Jorge Calles-Escandon; Jamehl Demons; Samantha Rogers; Kristina Cherry; Lata Menon; Ethel Kouba; Donna Davis; Marcie Burris; Sara J Byerly; Maggie C Y Ng; Nisa M Maruthur; Sanjay R Patel; Lawrence F Bielak; Leslie A Lange; Xiuqing Guo; Michèle M Sale; Kei Hang K Chan; Keri L Monda; Gary K Chen; Kira Taylor; Cameron Palmer; Todd L Edwards; Kari E North; Christopher A Haiman; Donald W Bowden; Barry I Freedman; Carl D Langefeld; Swapan K Das
Journal:  Hum Genet       Date:  2016-05-19       Impact factor: 4.132

5.  Integrative Analysis of Glucometabolic Traits, Adipose Tissue DNA Methylation, and Gene Expression Identifies Epigenetic Regulatory Mechanisms of Insulin Resistance and Obesity in African Americans.

Authors:  Neeraj K Sharma; Mary E Comeau; Dennis Montoya; Matteo Pellegrini; Timothy D Howard; Carl D Langefeld; Swapan K Das
Journal:  Diabetes       Date:  2020-09-14       Impact factor: 9.461

6.  The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue.

Authors:  Rebecca C Schugar; Diana M Shih; Manya Warrier; Robert N Helsley; Amy Burrows; Daniel Ferguson; Amanda L Brown; Anthony D Gromovsky; Markus Heine; Arunachal Chatterjee; Lin Li; Xinmin S Li; Zeneng Wang; Belinda Willard; YongHong Meng; Hanjun Kim; Nam Che; Calvin Pan; Richard G Lee; Rosanne M Crooke; Mark J Graham; Richard E Morton; Carl D Langefeld; Swapan K Das; Lawrence L Rudel; Nizar Zein; Arthur J McCullough; Srinivasan Dasarathy; W H Wilson Tang; Bernadette O Erokwu; Chris A Flask; Markku Laakso; Mete Civelek; Sathyamangla V Naga Prasad; Joerg Heeren; Aldons J Lusis; Stanley L Hazen; J Mark Brown
Journal:  Cell Rep       Date:  2017-06-20       Impact factor: 9.423

7.  Adiponectin Isoform Patterns in Ethnic-Specific ADIPOQ Mutation Carriers: The IRAS Family Study.

Authors:  Keri L Tabb; Chuan Gao; Pamela J Hicks; Gregory A Hawkins; Jerome I Rotter; Yii-Der Ida Chen; Xiuqing Guo; Jill M Norris; Carlos Lorenzo; Barry I Freedman; Donald W Bowden; Nicholette D Palmer
Journal:  Obesity (Silver Spring)       Date:  2017-06-23       Impact factor: 5.002

8.  Genetic Regulation of Enoyl-CoA Hydratase Domain-Containing 3 in Adipose Tissue Determines Insulin Sensitivity in African Americans and Europeans.

Authors:  Neeraj K Sharma; Chia-Chi Chuang Key; Mete Civelek; Martin Wabitsch; Mary E Comeau; Carl D Langefeld; John S Parks; Swapan K Das
Journal:  Diabetes       Date:  2019-04-22       Impact factor: 9.461

9.  Sex differences in human adipose tissue gene expression and genetic regulation involve adipogenesis.

Authors:  Warren D Anderson; Joon Yuhl Soh; Sarah E Innis; Alexis Dimanche; Lijiang Ma; Carl D Langefeld; Mary E Comeau; Swapan K Das; Eric E Schadt; Johan L M Björkegren; Mete Civelek
Journal:  Genome Res       Date:  2020-09-23       Impact factor: 9.043

10.  Transcriptional Regulatory Mechanisms in Adipose and Muscle Tissue Associated with Composite Glucometabolic Phenotypes.

Authors:  Carl D Langefeld; Mary E Comeau; Neeraj K Sharma; Donald W Bowden; Barry I Freedman; Swapan K Das
Journal:  Obesity (Silver Spring)       Date:  2018-01-29       Impact factor: 5.002
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