| Literature DB >> 26789102 |
Merih Oray1,2,3, Khawla Abu Samra1,2, Nazanin Ebrahimiadib1,2, Halea Meese1,2, C Stephen Foster1,2,4.
Abstract
INTRODUCTION: Glucocorticoids represent the standard therapy for reducing inflammation and immune activation in various diseases. However, as with any potent medication, they are not without side effects. Glucocorticoid-associated side effects may involve most major organ systems. Musculoskeletal, gastrointestinal, cardiovascular, endocrine, neuropsychiatric, dermatologic, ocular, and immunologic side effects are all possible. AREAS COVERED: This article analyzes English-language literature and provides an update on the most recent literature regarding side effects of systemic glucocorticoid treatment. EXPERT OPINION: The risk/benefit ratio of glucocorticoid therapy can be improved by proper use. Careful monitoring and using appropriate preventive strategies can potentially minimize side effects.Entities:
Keywords: corticosteroids; glucocorticoids; immunosuppression; side effects
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Year: 2016 PMID： 26789102 DOI： 10.1517/14740338.2016.1140743
Source DB: PubMed Journal: Expert Opin Drug Saf ISSN： 1474-0338 Impact factor: 4.250