Literature DB >> 26785464

Understanding the origins of human cancer.

Ludmil B Alexandrov1.   

Abstract

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Year:  2015        PMID： 26785464     DOI： 10.1126/science.aad7363

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


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  12 in total

1.  Mutational signatures associated with tobacco smoking in human cancer.

Authors:  Ludmil B Alexandrov; Young Seok Ju; Kerstin Haase; Peter Van Loo; Iñigo Martincorena; Serena Nik-Zainal; Yasushi Totoki; Akihiro Fujimoto; Hidewaki Nakagawa; Tatsuhiro Shibata; Peter J Campbell; Paolo Vineis; David H Phillips; Michael R Stratton
Journal:  Science       Date:  2016-11-04       Impact factor: 47.728

2.  A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer.

Authors:  Alessandra Viel; Alessandro Bruselles; Ettore Meccia; Mara Fornasarig; Michele Quaia; Vincenzo Canzonieri; Eleonora Policicchio; Emanuele Damiano Urso; Marco Agostini; Maurizio Genuardi; Emanuela Lucci-Cordisco; Tiziana Venesio; Aline Martayan; Maria Grazia Diodoro; Lupe Sanchez-Mete; Vittoria Stigliano; Filomena Mazzei; Francesca Grasso; Alessandro Giuliani; Marta Baiocchi; Roberta Maestro; Giuseppe Giannini; Marco Tartaglia; Ludmil B Alexandrov; Margherita Bignami
Journal:  EBioMedicine       Date:  2017-04-13       Impact factor: 8.143

3.  Revertant mosaicism repairs skin lesions in a patient with keratitis-ichthyosis-deafness syndrome by second-site mutations in connexin 26.

Authors:  Sanna Gudmundsson; Maria Wilbe; Sara Ekvall; Adam Ameur; Nicola Cahill; Ludmil B Alexandrov; Marie Virtanen; Maritta Hellström Pigg; Anders Vahlquist; Hans Törmä; Marie-Louise Bondeson
Journal:  Hum Mol Genet       Date:  2017-03-15       Impact factor: 6.150

4.  Identification and characterization of HPV-independent cervical cancers.

Authors:  Carolyn E Banister; Changlong Liu; Lucia Pirisi; Kim E Creek; Phillip J Buckhaults
Journal:  Oncotarget       Date:  2017-02-21

5.  Establishment and genomic characterization of gingivobuccal carcinoma cell lines with smokeless tobacco associated genetic alterations and oncogenic PIK3CA mutation.

Authors:  Kshama Pansare; Nilesh Gardi; Sayee Kamat; Prerana Dange; Rahul Previn; Poonam Gera; Pradnya Kowtal; Kishore Amin; Rajiv Sarin
Journal:  Sci Rep       Date:  2019-06-04       Impact factor: 4.379

6.  IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease.

Authors:  Hsiao-Yen Ma; Gen Yamamoto; Jun Xu; Xiao Liu; Daniel Karin; Ju Youn Kim; Ludmil B Alexandrov; Yukinori Koyama; Takahiro Nishio; Chris Benner; Sven Heinz; Sara B Rosenthal; Shuang Liang; Mengxi Sun; Gabriel Karin; Peng Zhao; Pnina Brodt; Iain H Mckillop; Oswald Quehenberger; Ed Dennis; Alan Saltiel; Hidekazu Tsukamoto; Bin Gao; Michael Karin; David A Brenner; Tatiana Kisseleva
Journal:  J Hepatol       Date:  2019-12-31       Impact factor: 25.083

7.  Identifying a Clinically Applicable Mutational Burden Threshold as a Potential Biomarker of Response to Immune Checkpoint Therapy in Solid Tumors.

Authors:  Anshuman Panda; Anil Betigeri; Kalyanasundaram Subramanian; Jeffrey S Ross; Dean C Pavlick; Siraj Ali; Paul Markowski; Ann Silk; Howard L Kaufman; Edmund Lattime; Janice M Mehnert; Ryan Sullivan; Christine M Lovly; Jeffrey Sosman; Douglas B Johnson; Gyan Bhanot; Shridar Ganesan
Journal:  JCO Precis Oncol       Date:  2017-12-07

8.  Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours.

Authors:  Xiaotu Ma; Yu Liu; Yanling Liu; Ludmil B Alexandrov; Michael N Edmonson; Charles Gawad; Xin Zhou; Yongjin Li; Michael C Rusch; John Easton; Robert Huether; Veronica Gonzalez-Pena; Mark R Wilkinson; Leandro C Hermida; Sean Davis; Edgar Sioson; Stanley Pounds; Xueyuan Cao; Rhonda E Ries; Zhaoming Wang; Xiang Chen; Li Dong; Sharon J Diskin; Malcolm A Smith; Jaime M Guidry Auvil; Paul S Meltzer; Ching C Lau; Elizabeth J Perlman; John M Maris; Soheil Meshinchi; Stephen P Hunger; Daniela S Gerhard; Jinghui Zhang
Journal:  Nature       Date:  2018-02-28       Impact factor: 49.962

Review 9.  High Risk of Hepatocellular Carcinoma Development in Fibrotic Liver: Role of the Hippo-YAP/TAZ Signaling Pathway.

Authors:  Hyuk Moon; Kyungjoo Cho; Sunyeong Shin; Do Young Kim; Kwang-Hyub Han; Simon Weonsang Ro
Journal:  Int J Mol Sci       Date:  2019-01-29       Impact factor: 5.923

10.  Whole-Exome Sequencing of Matched Primary and Metastatic Papillary Thyroid Cancer.

Authors:  Tariq Masoodi; Abdul K Siraj; Sarah Siraj; Saud Azam; Zeeshan Qadri; Wafaa N Albalawy; Sandeep Kumar Parvathareddy; Saif S Al-Sobhi; Fouad Al-Dayel; Fowzan S Alkuraya; Khawla S Al-Kuraya
Journal:  Thyroid       Date:  2019-12-04       Impact factor: 6.568
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