Literature DB >> 26783372

Lanthanide and asymmetric catalyzed syntheses of sterically hindered 4-isoxazolyl-1,4-dihydropyridines and 4-isoxazolyl-quinolones.

Scott A Steiger1, Chun Li2, Charles F Campana3, Nicholas R Natale1.   

Abstract

Entities:  

Year:  2016        PMID： 26783372      PMCID： PMC4714355          DOI： 10.1016/j.tetlet.2015.12.038

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN： 0040-4039            Impact factor:   2.415


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  11 in total

1.  Lipophilic 4-isoxazolyl-1,4-dihydropyridines: synthesis and structure-activity relationships.

Authors:  N R Natale; M E Rogers; R Staples; D J Triggle; A Rutledge
Journal:  J Med Chem       Date:  1999-08-12       Impact factor: 7.446

Review 2.  Ca2+ channel ligands: structure-function relationships of the 1,4-dihydropyridines.

Authors:  D J Triggle; D A Langs; R A Janis
Journal:  Med Res Rev       Date:  1989 Apr-Jun       Impact factor: 12.944

3.  Organocatalytic asymmetric three-component cyclization of cinnamaldehydes and primary amines with 1,3-dicarbonyl compounds: straightforward access to enantiomerically enriched dihydropyridines.

Authors:  Jun Jiang; Jie Yu; Xi-Xi Sun; Qin-Quan Rao; Liu-Zhu Gong
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

4.  Design, synthesis and 3D-QSAR studies of novel 1,4-dihydropyridines as TGFβ/Smad inhibitors.

Authors:  Daniel Längle; Viktoria Marquardt; Elena Heider; Brigita Vigante; Gunars Duburs; Iveta Luntena; Dirk Flötgen; Christopher Golz; Carsten Strohmann; Oliver Koch; Dennis Schade
Journal:  Eur J Med Chem       Date:  2015-03-14       Impact factor: 6.514

5.  Identification of dihydropyridines that reduce cellular tau levels.

Authors:  Christopher G Evans; Umesh K Jinwal; Leah N Makley; Chad A Dickey; Jason E Gestwicki
Journal:  Chem Commun (Camb)       Date:  2010-11-16       Impact factor: 6.222

6.  4-Isoxazolyl-1,4-dihydropyridines exhibit binding at the multidrug-resistance transporter.

Authors:  Victoria Hulubei; Scott B Meikrantz; David A Quincy; Tina Houle; John I McKenna; Mark E Rogers; Scott Steiger; N R Natale
Journal:  Bioorg Med Chem       Date:  2012-09-25       Impact factor: 3.641

Review 7.  4-isoxazolyl-1,4-dihydropyridines: a tale of two scaffolds.

Authors:  Nicholas R Natale; Scott A Steiger
Journal:  Future Med Chem       Date:  2014-05       Impact factor: 3.808

8.  Decoration of dihydropyrimidine and dihydropyridine scaffolds with sugars via Biginelli and Hantzsch multicomponent reactions: an efficient entry to a collection of artificial nucleosides.

Authors:  Alessandro Dondoni; Alessandro Massi
Journal:  Mol Divers       Date:  2003       Impact factor: 2.943

9.  Synthesis and SAR of b-annulated 1,4-dihydropyridines define cardiomyogenic compounds as novel inhibitors of TGFβ signaling.

Authors:  Dennis Schade; Marion Lanier; Erik Willems; Karl Okolotowicz; Paul Bushway; Christine Wahlquist; Cynthia Gilley; Mark Mercola; John R Cashman
Journal:  J Med Chem       Date:  2012-11-06       Impact factor: 7.446

10.  Unique structure-activity relationship for 4-isoxazolyl-1,4-dihydropyridines.

Authors:  Gerald W Zamponi; Stephanie C Stotz; Richard J Staples; Tina M Andro; Jared K Nelson; Victoria Hulubei; Alex Blumenfeld; Nicholas R Natale
Journal:  J Med Chem       Date:  2003-01-02       Impact factor: 7.446
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  1 in total

1.  Dimeric isoxazolyl-1,4-dihydropyridines have enhanced binding at the multi-drug resistance transporter.

Authors:  Scott A Steiger; Chun Li; Donald S Backos; Philip Reigan; N R Natale
Journal:  Bioorg Med Chem       Date:  2017-04-08       Impact factor: 3.641
  1 in total

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