Davy Vancampfort1, Brendon Stubbs2, Michel Probst3, Marc De Hert4, Felipe B Schuch5, James Mugisha6, Philip B Ward7, Simon Rosenbaum7. 1. KU Leuven - University of Leuven Department of Rehabilitation Sciences, Leuven, Belgium; KU Leuven - University of Leuven, Z.org UPC Leuven, campus Kortenberg, Kortenberg, Belgium. Electronic address: davy.vancampfort@uc-kortenberg.be. 2. Physiotherapy Department, South London and Maudsley NHS Foundation Trust, Denmark Hill, London SE5 8AZ, United Kingdom; Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London Box SE5 8AF, United Kingdom. 3. KU Leuven - University of Leuven Department of Rehabilitation Sciences, Leuven, Belgium. 4. KU Leuven - University of Leuven, Z.org UPC Leuven, campus Kortenberg, Kortenberg, Belgium. 5. Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil; Programa de Pos Graduacaoem Ciencias Medicas: Psiquiatria, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. 6. Butabika National Referral and Mental Health Hospital, Kampala, Uganda. 7. School of Psychiatry, University of New South Wales, Sydney, Australia.
Abstract
AIM: This study investigated whether in patients with schizophrenia the Physical Activity Vital Sign (PAVS) assessment can identify those at higher risk of cardio-metabolic abnormalities. METHODS: One hundred patients with schizophrenia completed the PAVS-questions exploring whether they adhered to the general physical activity recommendations, underwent a full-fasting metabolic screening, and performed a six-minute walk test (6 MWT). RESULTS: Those who do not adhere to the health recommendations according to the PAVS (n=61) were significantly older (37.1±11.3 versus 32.5±8.5 years, P=0.033) and more likely to be women (30/36 versus 31/64, P<0.001). Patients who do not meet the physical activity recommendations have a higher BMI (27.0±6.4 versus 23.3±3.1, P=0.017) performed worse on the 6MWT (531.1±84.2 m versus 657.0±98.2 m, P<0.001) and are at a significantly higher risk for cardio-metabolic diseases. Relative risks ranged from 1.07 (0.84-1.36) for having dyslipidemia to 4.65 (1.77-12.17) for having hypertension. CONCLUSIONS: PAVS-baseline assessment should be included in the routine assessment of people with schizophrenia.
AIM: This study investigated whether in patients with schizophrenia the Physical Activity Vital Sign (PAVS) assessment can identify those at higher risk of cardio-metabolic abnormalities. METHODS: One hundred patients with schizophrenia completed the PAVS-questions exploring whether they adhered to the general physical activity recommendations, underwent a full-fasting metabolic screening, and performed a six-minute walk test (6 MWT). RESULTS: Those who do not adhere to the health recommendations according to the PAVS (n=61) were significantly older (37.1±11.3 versus 32.5±8.5 years, P=0.033) and more likely to be women (30/36 versus 31/64, P<0.001). Patients who do not meet the physical activity recommendations have a higher BMI (27.0±6.4 versus 23.3±3.1, P=0.017) performed worse on the 6MWT (531.1±84.2 m versus 657.0±98.2 m, P<0.001) and are at a significantly higher risk for cardio-metabolic diseases. Relative risks ranged from 1.07 (0.84-1.36) for having dyslipidemia to 4.65 (1.77-12.17) for having hypertension. CONCLUSIONS: PAVS-baseline assessment should be included in the routine assessment of people with schizophrenia.
Authors: Brendon Stubbs; Ai Koyanagi; Felipe Schuch; Joseph Firth; Simon Rosenbaum; Fiona Gaughran; James Mugisha; Davy Vancampfort Journal: Schizophr Bull Date: 2017-05-01 Impact factor: 9.306
Authors: Davy Vancampfort; Brendon Stubbs; Marc De Hert; Christy du Plessis; Caleb Ademola Omuwa Gbiri; Jepkemoi Kibet; Nancy Wanyonyi; James Mugisha Journal: Pan Afr Med J Date: 2017-02-28
Authors: Amanda J Wheeler; Claire L O'Reilly; Sarira El-Den; Joshua Byrnes; Robert S Ware; Sara S McMillan Journal: BMJ Open Date: 2020-07-23 Impact factor: 2.692