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Literature DB >> 26782000

Psoriasis: Behind the scenes.

Abstract

Psoriasis is a chronic inflammatory skin disease characterized by a significant deterioration in the quality of life of affected individuals. Notably, psoriasis is significantly associated with cardiovascular and metabolic syndrome and other autoimmune disorders. Recent progress in biologic therapies has revealed the fundamental role of tumor necrosis factor-α, interleukin (IL)-23 and the IL-17A axis together with aberrant overproduction of epidermal IL-36γ in the pathogenesis of psoriasis. This review provides an update on the clinical, pathological and therapeutic advancements involving psoriasis.

Entities: Disease Gene

Keywords: interleukin-17; interleukin-23; interleukin-36γ; psoriasis; tumor necrosis factor-α

Mesh：

Substances：
Biological Products

Year: 2016 PMID： 26782000 DOI： 10.1111/1346-8138.13186

Source DB: PubMed Journal: J Dermatol ISSN： 0385-2407 Impact factor: 4.005

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Cited

11 in total

Review 1. Autoimmunity and autoimmune co-morbidities in psoriasis.

Authors: Kazuhisa Furue; Takamichi Ito; Gaku Tsuji; Takafumi Kadono; Takeshi Nakahara; Masutaka Furue
Journal: Immunology Date: 2018-02-06 Impact factor: 7.397

2. Metformin inhibits IL-1β secretion via impairment of NLRP3 inflammasome in keratinocytes: implications for preventing the development of psoriasis.

Authors: Gaku Tsuji; Akiko Hashimoto-Hachiya; Vu Hai Yen; Masaki Takemura; Ayako Yumine; Kazuhisa Furue; Masutaka Furue; Takeshi Nakahara
Journal: Cell Death Discov Date: 2020-03-04

Review 3. "Inflammatory skin march" in atopic dermatitis and psoriasis.

Authors: Masutaka Furue; Takafumi Kadono
Journal: Inflamm Res Date: 2017-06-15 Impact factor: 4.575

4. CNS-Specific Synthesis of Interleukin 23 Induces a Progressive Cerebellar Ataxia and the Accumulation of Both T and B Cells in the Brain: Characterization of a Novel Transgenic Mouse Model.

Authors: Louisa Nitsch; Julian Zimmermann; Marius Krauthausen; Markus J Hofer; Raman Saggu; Gabor C Petzold; Michael T Heneka; Daniel R Getts; Albert Becker; Iain L Campbell; Marcus Müller
Journal: Mol Neurobiol Date: 2019-06-02 Impact factor: 5.590

5. Variances in the mRNA expression profile of TGF-β1-3 isoforms and its TGF-βRI-III receptors during cyclosporin a treatment of psoriatic patients.

Authors: Anna Michalska-Bańkowska; Dominika Wcisło-Dziadecka; Beniamin Grabarek; Ligia Brzezińska-Wcisło; Urszula Mazurek; Natalia Salwowska; Mirosław Bańkowski
Journal: Postepy Dermatol Alergol Date: 2018-07-19 Impact factor: 1.837

6. Association between psoriasis and vitamin D: Duration of disease correlates with decreased vitamin D serum levels: An observational case-control study.

Authors: Angela Filoni; Michelangelo Vestita; Maurizio Congedo; Giuseppe Giudice; Silvio Tafuri; Domenico Bonamonte
Journal: Medicine (Baltimore) Date: 2018-06 Impact factor: 1.889

10. Metformin inhibits IL-1β secretion via impairment of NLRP3 inflammasome in keratinocytes: implications for preventing the development of psoriasis.