| Literature DB >> 26781252 |
Joshua Z Willey1, Amelia K Boehme2, Francesco Castagna3, Melana Yuzefpolskaya3, A Reshad Garan3, Veli Topkara3, Paolo C Colombo3.
Abstract
Stroke is one of the most dreaded complications of left ventricular assist device therapy in patients with end-stage congestive heart failure. There is strong evidence linking anticoagulation and infection with ischemic and hemorrhagic strokes, though recent data has emerged regarding the importance of elevated blood pressure. In the recently completed Heartware Ventricular Assist Device studies, a mean arterial pressure greater than 90 mmHg was associated with greater stroke risk, particularly the hemorrhagic subtype. In this review, we discuss recent evidence regarding deleterious effects of uncontrolled hypertension in patients with left ventricular devices, and propose measurement and management strategies.Entities:
Keywords: Hypertension; Left ventricular assist device; Stroke
Mesh:
Year: 2016 PMID: 26781252 PMCID: PMC5518745 DOI: 10.1007/s11906-015-0618-1
Source DB: PubMed Journal: Curr Hypertens Rep ISSN: 1522-6417 Impact factor: 5.369