Literature DB >> 26778926

Wireless, Ultra-Low-Power Implantable Sensor for Chronic Bladder Pressure Monitoring.

Steve J A Majerus1, Steven L Garverick1, Michael A Suster1, Paul C Fletter2, Margot S Damaser2.   

Abstract

The wireless implantable/intracavity micromanometer (WIMM) system was designed to fulfill the unmet need for a chronic bladder pressure sensing device in urological fields such as urodynamics for diagnosis and neuromodulation for bladder control. Neuromodulation in particular would benefit from a wireless bladder pressure sensor which could provide real-time pressure feedback to an implanted stimulator, resulting in greater bladder capacity while using less power. The WIMM uses custom integrated circuitry, a MEMS transducer, and a wireless antenna to transmit pressure telemetry at a rate of 10 Hz. Aggressive power management techniques yield an average current draw of 9 μA from a 3.6-Volt micro-battery, which minimizes the implant size. Automatic pressure offset cancellation circuits maximize the sensing dynamic range to account for drifting pressure offset due to environmental factors, and a custom telemetry protocol allows transmission with minimum overhead. Wireless operation of the WIMM has demonstrated that the external receiver can receive the telemetry packets, and the low power consumption allows for at least 24 hours of operation with a 4-hour wireless recharge session.

Keywords:  ASIC; Design; FSK transmitter; Measurement; ULP; bladder pressure; implant; low-power; neuromodulation; offset cancellation; urodynamics; wireless recharge; wireless sensor

Year:  2012        PMID: 26778926      PMCID: PMC4712728          DOI: 10.1145/2180878.2180883

Source DB:  PubMed          Journal:  ACM J Emerg Technol Comput Syst        ISSN: 1550-4832            Impact factor:   1.420


  11 in total

1.  The acute effects of continuous and conditional neuromodulation on the bladder in spinal cord injury.

Authors:  A P Kirkham; N C Shah; S L Knight; P J Shah; M D Craggs
Journal:  Spinal Cord       Date:  2001-08       Impact factor: 2.772

2.  Low-power wireless micromanometer system for acute and chronic bladder-pressure monitoring.

Authors:  Steve J A Majerus; Paul C Fletter; Margot S Damaser; Steven L Garverick
Journal:  IEEE Trans Biomed Eng       Date:  2010-10-07       Impact factor: 4.538

3.  Closed loop electrical control of urinary continence.

Authors:  Brian J Wenzel; Joseph W Boggs; Kenneth J Gustafson; Warren M Grill
Journal:  J Urol       Date:  2006-04       Impact factor: 7.450

4.  Feedback analysis and design of RF power links for low-power bionic systems.

Authors:  M W Baker; R Sarpeshkar
Journal:  IEEE Trans Biomed Circuits Syst       Date:  2007-03       Impact factor: 3.833

5.  A Mini-Invasive Long-Term Bladder Urine Pressure Measurement ASIC and System.

Authors: 
Journal:  IEEE Trans Biomed Circuits Syst       Date:  2008-03       Impact factor: 3.833

6.  Bladder inhibition by penile nerve stimulation in spinal cord injury patients.

Authors:  J S Wheeler; J S Walter; P J Zaszczurynski
Journal:  J Urol       Date:  1992-01       Impact factor: 7.450

7.  Comparison of air-charged and water-filled urodynamic pressure measurement catheters.

Authors:  M A Cooper; P C Fletter; P J Zaszczurynski; M S Damaser
Journal:  Neurourol Urodyn       Date:  2011-02-08       Impact factor: 2.696

8.  Conditional and continuous electrical stimulation increase cystometric capacity in persons with spinal cord injury.

Authors:  Eric E Horvath; Paul B Yoo; Cindy L Amundsen; George D Webster; Warren M Grill
Journal:  Neurourol Urodyn       Date:  2010-03       Impact factor: 2.696

9.  The reproducibility of urodynamic findings in healthy female volunteers: results of repeated studies in the same setting and after short-term follow-up.

Authors:  Amit Gupta; Gina Defreitas; Gary E Lemack
Journal:  Neurourol Urodyn       Date:  2004       Impact factor: 2.696

Review 10.  Primer: questionnaires versus urodynamics in the evaluation of lower urinary tract dysfunction-one, both or none?

Authors:  Christopher R Chapple
Journal:  Nat Clin Pract Urol       Date:  2005-11
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  6 in total

1.  Real-Time Classification of Bladder Events for Effective Diagnosis and Treatment of Urinary Incontinence.

Authors:  Robert Karam; Dennis Bourbeau; Steve Majerus; Iryna Makovey; Howard B Goldman; Margot S Damaser; Swarup Bhunia
Journal:  IEEE Trans Biomed Eng       Date:  2015-08-18       Impact factor: 4.538

Review 2.  Ambulatory urodynamic monitoring: state of the art and future directions.

Authors:  Benjamin Abelson; Steve Majerus; Daniel Sun; Bradley C Gill; Eboo Versi; Margot S Damaser
Journal:  Nat Rev Urol       Date:  2019-05       Impact factor: 14.432

3.  Is submucosal bladder pressure monitoring feasible?

Authors:  Anisha S Basu; Steve Majerus; Elizabeth Ferry; Iryna Makovey; Hui Zhu; Margot S Damaser
Journal:  Proc Inst Mech Eng H       Date:  2018-01-29       Impact factor: 1.617

4.  At-home genital nerve stimulation for individuals with SCI and neurogenic detrusor overactivity: A pilot feasibility study.

Authors:  Dennis J Bourbeau; Kenneth J Gustafson; Steven W Brose
Journal:  J Spinal Cord Med       Date:  2018-01-15       Impact factor: 1.985

5.  Suburothelial Bladder Contraction Detection with Implanted Pressure Sensor.

Authors:  Steve J A Majerus; Paul C Fletter; Elizabeth K Ferry; Hui Zhu; Kenneth J Gustafson; Margot S Damaser
Journal:  PLoS One       Date:  2017-01-06       Impact factor: 3.240

6.  Designing and Implementing an Implantable Wireless Micromanometer System for Real-Time Bladder Pressure Monitoring: A Preliminary Study.

Authors:  Yu-Ting Li; Ling-Yu Yang; Wei-Ting Hsu; Chih-Wei Peng
Journal:  Sensors (Basel)       Date:  2020-08-17       Impact factor: 3.576

  6 in total

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